| Valproic acid increases the SMN2 protein level: a well-known drug as a potential therapy for spinal muscular atrophy L Brichta, Y Hofmann, E Hahnen, FA Siebzehnrubl, H Raschke, I Blumcke, ... Human molecular genetics 12 (19), 2481-2489, 2003 | 528 | 2003 |
| ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner D Chen, Z Fan, M Rauh, M Buchfelder, IY Eyupoglu, N Savaskan Oncogene 36 (40), 5593-5608, 2017 | 349 | 2017 |
| Common mutations of β-catenin in adamantinomatous craniopharyngiomas but not in other tumours originating from the sellar region R Buslei, M Nolde, B Hofmann, S Meissner, IY Eyupoglu, F Siebzehnrübl, ... Acta neuropathologica 109, 589-597, 2005 | 282 | 2005 |
| Histone deacetylase inhibitors: possible implications for neurodegenerative disorders E Hahnen, J Hauke, C Tränkle, IY Eyüpoglu, B Wirth, I Blümcke Expert opinion on investigational drugs 17 (2), 169-184, 2008 | 257 | 2008 |
| Long-term analysis of the NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with PCV or temozolomide W Wick, P Roth, C Hartmann, P Hau, M Nakamura, F Stockhammer, ... Neuro-oncology 18 (11), 1529-1537, 2016 | 229 | 2016 |
| Regulation of microglial expression of integrins by poly (ADP-ribose) polymerase-1 O Ullrich, A Diestel, IY Eyüpoglu, R Nitsch Nature cell biology 3 (12), 1035-1042, 2001 | 229 | 2001 |
| Selenium deficiency increases susceptibility to glutamate‐induced excitotoxicity NE Savaskan, AU Bräuer, M Kühbacher, IY Eyüpoglu, A Kyriakopoulos, ... The FASEB Journal 17 (1), 112-114, 2003 | 216 | 2003 |
| Small interfering RNA–mediated xCT silencing in gliomas inhibits neurodegeneration and alleviates brain edema NE Savaskan, A Heckel, E Hahnen, T Engelhorn, A Doerfler, O Ganslandt, ... Nature medicine 14 (6), 629-632, 2008 | 211 | 2008 |
| In vitro and ex vivo evaluation of second‐generation histone deacetylase inhibitors for the treatment of spinal muscular atrophy E Hahnen, IY Eyüpoglu, L Brichta, K Haastert, C Tränkle, FA Siebzehnrübl, ... Journal of neurochemistry 98 (1), 193-202, 2006 | 204 | 2006 |
| Surgical resection of malignant gliomas—role in optimizing patient outcome IY Eyüpoglu, M Buchfelder, NE Savaskan Nature Reviews Neurology 9 (3), 141-151, 2013 | 180 | 2013 |
| Survival motor neuron gene 2 silencing by DNA methylation correlates with spinal muscular atrophy disease severity and can be bypassed by histone … J Hauke, M Riessland, S Lunke, IY Eyüpoglu, I Blümcke, A El-Osta, ... Human molecular genetics 18 (2), 304-317, 2009 | 162 | 2009 |
| Suberoylanilide hydroxamic acid (SAHA) has potent anti‐glioma properties in vitro, ex vivo and in vivo IY Eyüpoglu, E Hahnen, R Buslei, FA Siebzehnrübl, NE Savaskan, ... Journal of neurochemistry 93 (4), 992-999, 2005 | 149 | 2005 |
| Improving the extent of malignant glioma resection by dual intraoperative visualization approach IY Eyüpoglu, N Hore, NE Savaskan, P Grummich, K Roessler, ... Public Library of Science 7 (9), e44885, 2012 | 147 | 2012 |
| The sitting position in neurosurgery: indications, complications and results. a single institution experience of 600 cases O Ganslandt, A Merkel, H Schmitt, A Tzabazis, M Buchfelder, I Eyupoglu, ... Acta neurochirurgica 155, 1887-1893, 2013 | 130 | 2013 |
| Cellular characterization of the peritumoral edema zone in malignant brain tumors T Engelhorn, NE Savaskan, MA Schwarz, J Kreutzer, EP Meyer, ... Cancer science 100 (10), 1856-1862, 2009 | 130 | 2009 |
| MIF-CD74 signaling impedes microglial M1 polarization and facilitates brain tumorigenesis A Ghoochani, MA Schwarz, E Yakubov, T Engelhorn, A Doerfler, ... Oncogene 35 (48), 6246-6261, 2016 | 122 | 2016 |
| Histone deacetylase inhibitors increase neuronal differentiation in adult forebrain precursor cells FA Siebzehnrubl, R Buslei, IY Eyupoglu, S Seufert, E Hahnen, I Blumcke Experimental Brain Research 176, 672-678, 2007 | 122 | 2007 |
| Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema T Sehm, Z Fan, A Ghoochani, M Rauh, T Engelhorn, G Minakaki, A Dörfler, ... Oncotarget 7 (24), 36021, 2016 | 120 | 2016 |
| Lessons from the bone marrow: how malignant glioma cells attract adult haematopoietic progenitor cells G Tabatabai, O Bähr, R Möhle, IY Eyüpoglu, AM Boehmler, J Wischhusen, ... Brain 128 (9), 2200-2211, 2005 | 114 | 2005 |
| Temozolomide toxicity operates in a xCT/SLC7a11 dependent manner and is fostered by ferroptosis T Sehm, M Rauh, K Wiendieck, M Buchfelder, IIY Eyüpoglu, NE Savaskan Oncotarget 7 (46), 74630, 2016 | 110 | 2016 |
