Multidimensional heuristic process for high-yield production of astaxanthin and fragrance molecules in Escherichia coli C Zhang, VY Seow, X Chen, HP Too Nature Communications 9 (1), 1858, 2018 | 133 | 2018 |
Microbial astaxanthin biosynthesis: recent achievements, challenges, and commercialization outlook C Zhang, X Chen, HP Too Applied Microbiology and Biotechnology 104 (13), 5725-5737, 2020 | 129 | 2020 |
Systematic engineering for high-yield production of viridiflorol and amorphadiene in auxotrophic Escherichia coli S Shukal, X Chen, C Zhang Metabolic engineering 55, 170-178, 2019 | 94 | 2019 |
Efflux transporter engineering markedly improves amorphadiene production in Escherichia coli C Zhang, X Chen, G Stephanopoulos, HP Too Biotechnology and bioengineering 113 (8), 1755-1763, 2016 | 85 | 2016 |
A “plug‐n‐play” modular metabolic system for the production of apocarotenoids C Zhang, X Chen, ND Lindley, HP Too Biotechnology and bioengineering 115 (1), 174-183, 2018 | 76 | 2018 |
Combining genotype improvement and statistical media optimization for isoprenoid production in E. coli C Zhang, X Chen, R Zou, K Zhou, G Stephanopoulos, HP Too PLoS One 8 (10), e75164, 2013 | 69 | 2013 |
Statistical experimental design guided optimization of a one-pot biphasic multienzyme total synthesis of amorpha-4, 11-diene X Chen, C Zhang, R Zou, K Zhou, G Stephanopoulos, HP Too PloS one 8 (11), e79650, 2013 | 59 | 2013 |
Agrocybe aegerita Serves As a Gateway for Identifying Sesquiterpene Biosynthetic Enzymes in Higher Fungi C Zhang, X Chen, A Orban, S Shukal, F Birk, HP Too, M Rühl ACS Chemical Biology 15 (5), 1268-1277, 2020 | 57 | 2020 |
Metabolic engineering strategies for sustainable terpenoid flavor and fragrance synthesis X Chen, C Zhang, ND Lindley Journal of agricultural and food chemistry 68 (38), 10252-10264, 2019 | 49 | 2019 |
Experimental design-aided systematic pathway optimization of glucose uptake and deoxyxylulose phosphate pathway for improved amorphadiene production C Zhang, R Zou, X Chen, G Stephanopoulos, HP Too Applied microbiology and biotechnology 99, 3825-3837, 2015 | 43 | 2015 |
In Vitro Metabolic Engineering of Amorpha-4,11-diene Biosynthesis at Enhanced Rate and Specific Yield of Production X Chen, C Zhang, R Zou, G Stephanopoulos, HP Too ACS synthetic biology 6 (9), 1691-1700, 2017 | 32 | 2017 |
Bioinformatics-aided identification, characterization and applications of mushroom linalool synthases C Zhang, X Chen, RTC Lee, S Maurer-Stroh, M Rühl Communications Biology 4 (1), 223, 2021 | 29 | 2021 |
Integrating enzyme and metabolic engineering tools for enhanced α-ionone production X Chen, S Shukal, C Zhang Journal of agricultural and food chemistry 67 (49), 13451-13459, 2019 | 28 | 2019 |
Biotechnological applications of S-adenosyl-methionine-dependent methyltransferases for natural products biosynthesis and diversification C Zhang, SA Sultan, X Chen Bioresources and Bioprocessing 8 (1), 72, 2021 | 22 | 2021 |
Multienzyme biosynthesis of dihydroartemisinic acid X Chen, C Zhang, HP Too Molecules 22 (9), 1422, 2017 | 21 | 2017 |
High-level de novo biosynthesis of glycosylated zeaxanthin and astaxanthin in Escherichia coli X Chen, X Lim, A Bouin, T Lautier, C Zhang Bioresources and Bioprocessing 8, 1-13, 2021 | 20 | 2021 |
Metabolic engineering of Escherichia coli BL21 strain using simplified CRISPR-Cas9 and asymmetric homology arms recombineering S Shukal, XH Lim, C Zhang, X Chen Microbial Cell Factories 21 (1), 19, 2022 | 17 | 2022 |
Total enzymatic synthesis of cis-α-irone from a simple carbon source X Chen, J Esque, C Zhang, S Shukal, CC Lim, L Ong, D Smith, I André Nature Communications 13 (1), 7421, 2022 | 11 | 2022 |
High-Yield Biosynthesis of trans-Nerolidol from Sugar and Glycerol N Tan, L Ong, S Shukal, X Chen, C Zhang Journal of Agricultural and Food Chemistry 71 (22), 8479-8487, 2023 | 7 | 2023 |
β-Cryptoxanthin Production in Escherichia coli by Optimization of the Cytochrome P450 CYP97H1 Activity T Lautier, DJ Smith, LK Yang, X Chen, C Zhang, G Truan, ND Lindley Journal of Agricultural and Food Chemistry 71 (11), 4683-4695, 2023 | 3 | 2023 |