Structure-activity relationships of oleanane-and ursane-type triterpenoids H Sun, WS Fang, WZ Wang, C Hu Botanical Studies 47 (4), 339-368, 2006 | 165 | 2006 |
Medicinal chemistry of bioactive natural products X Liang, WS Fang Wiley, 2006 | 142 | 2006 |
Anti-tumor activity of a 3-oxo derivative of oleanolic acid D Huang, Y Ding, Y Li, W Zhang, W Fang, X Chen Cancer letters 233 (2), 289-296, 2006 | 114 | 2006 |
Anti-inflammatory and analgesic effects of ethanol and aqueous extracts of Pterocephalus hookeri (CB Clarke) Höeck L Zhang, JJ Hu, JW Lin, WS Fang, GH Du Journal of ethnopharmacology 123 (3), 510-514, 2009 | 81 | 2009 |
Recent progress in structure activity relationship and mechanistic studies of taxol analogues WS Fang, XT Liang Mini reviews in medicinal chemistry 5 (1), 1-12, 2005 | 81 | 2005 |
Optimization of taxane binding to microtubules: binding affinity dissection and incremental construction of a high-affinity analog of paclitaxel R Matesanz, I Barasoain, CG Yang, L Wang, X Li, C De Ines, C Coderch, ... Chemistry & biology 15 (6), 573-585, 2008 | 75 | 2008 |
Bioactive coumarins from Boenninghausenia sessilicarpa QY Yang, XY Tian, WS Fang Journal of Asian natural products research 9 (1), 59-65, 2007 | 71 | 2007 |
Lx2-32c, a novel semi-synthetic taxane, exerts antitumor activity against prostate cancer cells in vitro and in vivo G Lv, D Sun, J Zhang, X Xie, X Wu, W Fang, J Tian, C Yan, H Wang, F Fu Acta Pharmaceutica Sinica B 7 (1), 52-58, 2017 | 63 | 2017 |
On the chemical constituents of Dipsacus asper XY Tian, YH Wang, HY Liu, SS Yu, WS Fang Chemical and pharmaceutical bulletin 55 (12), 1677-1681, 2007 | 58 | 2007 |
Qualitative and quantitative determination of taxol and related compounds in Taxus cuspidata Sieb et Zucc W Fang, Y Wu, J Zhou, W Chen, Q Fang Phytochemical Analysis 4 (3), 115-119, 1993 | 53 | 1993 |
Pentacyclic triterpenoids and their saponins with apoptosis-inducing activity SR Wang, WS Fang Current Topics in Medicinal Chemistry 9 (16), 1581-1596, 2009 | 52 | 2009 |
Lx2-32c, a novel taxane and its antitumor activities in vitro and in vivo H Wang, H Li, M Zuo, Y Zhang, H Liu, W Fang, X Chen Cancer letters 268 (1), 89-97, 2008 | 49 | 2008 |
BACE1 (beta-secretase) inhibitory chromone glycosides from Aloe vera and Aloe nobilis. L Lv, QY Yang, Y Zhao, CS Yao, Y Sun, EJ Yang, KS Song, I Mook-Jung, ... Planta medica 74 (5), 540-545, 2008 | 49 | 2008 |
Taxanes convert regions of perturbed microtubule growth into rescue sites A Rai, T Liu, S Glauser, EA Katrukha, J Estévez-Gallego, ... Nature Materials 19 (3), 355-365, 2020 | 46 | 2020 |
Taxachitrienes A and B, two new bicyclic taxane diterpenoids from Taxus chinensis WS Fang, QC Fang, XT Liang, Y Lu, QT Zheng Tetrahedron 51 (31), 8483-8490, 1995 | 45 | 1995 |
A series of enthalpically optimized docetaxel analogues exhibiting enhanced antitumor activity and water solubility YT Ma, Y Yang, P Cai, DY Sun, PA Sánchez-Murcia, XY Zhang, WQ Jia, ... Journal of natural products 81 (3), 524-533, 2018 | 42 | 2018 |
Overcoming Tumor Drug Resistance with High‐Affinity Taxanes: A SAR Study of C2‐Modified 7‐Acyl‐10‐Deacetyl Cephalomannines CG Yang, I Barasoain, X Li, R Matesanz, R Liu, FJ Sharom, DL Yin, ... ChemMedChem: Chemistry Enabling Drug Discovery 2 (5), 691-701, 2007 | 42 | 2007 |
Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances R Matesanz, C Trigili, J Rodríguez-Salarichs, I Zanardi, B Pera, A Nogales, ... Bioorganic & Medicinal Chemistry 22 (18), 5078-5090, 2014 | 39 | 2014 |
Synthesis and biological evaluation of colchicine B-ring analogues tethered with halogenated benzyl moieties L Cosentino, M Redondo-Horcajo, Y Zhao, AR Santos, KF Chowdury, ... Journal of Medicinal Chemistry 55 (24), 11062-11066, 2012 | 36 | 2012 |
Lx2-32c, a novel taxane derivative, exerts anti-resistance activity by initiating intrinsic apoptosis pathway in vitro and inhibits the growth of resistant tumor in vivo Q Zhou, Y Li, J Jin, L Lang, Z Zhu, W Fang, X Chen Biological and Pharmaceutical Bulletin 35 (12), 2170-2179, 2012 | 36 | 2012 |