Acquisition of murine NK cell cytotoxicity requires the translation of a pre-existing pool of granzyme B and perforin mRNAs TA Fehniger, SF Cai, X Cao, AJ Bredemeyer, RM Presti, AR French, ... Immunity 26 (6), 798-811, 2007 | 510 | 2007 |
Clinical next‐generation sequencing in patients with non–small cell lung cancer IS Hagemann, S Devarakonda, CM Lockwood, DH Spencer, K Guebert, ... Cancer 121 (4), 631-639, 2015 | 236 | 2015 |
The orphan granzymes of humans and mice WJ Grossman, PA Revell, ZH Lu, H Johnson, AJ Bredemeyer, TJ Ley Current opinion in immunology 15 (5), 544-552, 2003 | 214 | 2003 |
Validation of a next-generation sequencing assay for clinical molecular oncology CE Cottrell, H Al-Kateb, AJ Bredemeyer, EJ Duncavage, DH Spencer, ... The Journal of molecular diagnostics 16 (1), 89-105, 2014 | 203 | 2014 |
Performance of common analysis methods for detecting low-frequency single nucleotide variants in targeted next-generation sequence data DH Spencer, M Tyagi, F Vallania, AJ Bredemeyer, JD Pfeifer, RD Mitra, ... The Journal of Molecular Diagnostics 16 (1), 75-88, 2014 | 163 | 2014 |
A proteomic approach for the discovery of protease substrates AJ Bredemeyer, RM Lewis, JP Malone, AE Davis, J Gross, RR Townsend, ... Proceedings of the National Academy of Sciences 101 (32), 11785-11790, 2004 | 145 | 2004 |
The transcription factor MIST1 is a novel human gastric chief cell marker whose expression is lost in metaplasia, dysplasia, and carcinoma JKM Lennerz, SH Kim, EL Oates, WJ Huh, JM Doherty, X Tian, ... The American journal of pathology 177 (3), 1514-1533, 2010 | 143 | 2010 |
XBP1 controls maturation of gastric zymogenic cells by induction of MIST1 and expansion of the rough endoplasmic reticulum WJ Huh, E Esen, JH Geahlen, AJ Bredemeyer, AH Lee, G Shi, ... Gastroenterology 139 (6), 2038-2049, 2010 | 134 | 2010 |
RAB26 and RAB3D are direct transcriptional targets of MIST1 that regulate exocrine granule maturation X Tian, RU Jin, AJ Bredemeyer, EJ Oates, KM Błażewska, CE McKenna, ... Molecular and cellular biology 30 (5), 1269-1284, 2010 | 111 | 2010 |
The gastric epithelial progenitor cell niche and differentiation of the zymogenic (chief) cell lineage AJ Bredemeyer, JH Geahlen, VG Weis, WJ Huh, BH Zinselmeyer, ... Developmental biology 325 (1), 211-224, 2009 | 109 | 2009 |
Detection of gene rearrangements in targeted clinical next-generation sequencing HJ Abel, H Al-Kateb, CE Cottrell, AJ Bredemeyer, CC Pritchard, ... The Journal of Molecular Diagnostics 16 (4), 405-417, 2014 | 85 | 2014 |
Occult specimen contamination in routine clinical next-generation sequencing testing JK Sehn, DH Spencer, JD Pfeifer, AJ Bredemeyer, CE Cottrell, HJ Abel, ... American journal of clinical pathology 144 (4), 667-674, 2015 | 41 | 2015 |
Transcription factor MIST1 in terminal differentiation of mouse and human plasma cells BJ Capoccia, JKM Lennerz, AJ Bredemeyer, JM Klco, JL Frater, JC Mills Physiological genomics 43 (3), 174-186, 2011 | 34 | 2011 |
Hop cleavage and function in granzyme B-induced apoptosis AJ Bredemeyer, PE Carrigan, TA Fehniger, DF Smith, TJ Ley Journal of Biological Chemistry 281 (48), 37130-37141, 2006 | 29 | 2006 |
Clinical genomicist workstation. MK Sharma, J Phillips, S Agarwal, WS Wiggins, S Shrivastava, SB Koul, ... AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits …, 2013 | 21 | 2013 |
A wide spectrum of EGFR mutations in glioblastoma is detected by a single clinical oncology targeted next-generation sequencing panel PJ Cimino, A Bredemeyer, HJ Abel, EJ Duncavage Experimental and molecular pathology 98 (3), 568-573, 2015 | 18 | 2015 |
Use of protease proteomics to discover granzyme B substrates AJ Bredemeyer, RR Townsend, TJ Ley Immunologic research 32, 143-153, 2005 | 18 | 2005 |
Functional analysis of the phenobarbital-responsive unit in rat CYP2B2 S Liu, I Rivera-Rivera, AJ Bredemeyer, B Kemper Biochemical pharmacology 62 (1), 21-28, 2001 | 17 | 2001 |
Targeted Hybrid-Capture for Somatic Mutation Detection in the Clinic CE Cottrell, AJ Bredemeyer, H Al-Kateb Clinical Genomics, 321-341, 2015 | 1 | 2015 |
Orthogonal Approaches to Validate the Velsera Knowledgebase, a Precision Oncology Knowledgebase That Supports Automated Reporting of Clinically Relevant Somatic Cancer Variants A Bredemeyer, G Nanda, A Jedhe, A Phatak, N Deshmukh, V Iyer, ... JOURNAL OF MOLECULAR DIAGNOSTICS 25 (11), S108-S108, 2023 | | 2023 |