フォロー
Christopher D Wiley
Christopher D Wiley
Assistant Professor, Tufts University
確認したメール アドレス: tufts.edu
タイトル
引用先
引用先
Mitochondrial dysfunction induces senescence with a distinct secretory phenotype
CD Wiley, MC Velarde, P Lecot, SU Liu, EA Sarnoski, A Freund, ...
Cell metabolism 23 (2), 303-314, 2016
9762016
Mitochondrial effectors of cellular senescence: beyond the free radical theory of aging
DV Ziegler, CD Wiley, MC Velarde
Aging cell 14 (1), 1-7, 2015
3762015
From ancient pathways to aging cells—connecting metabolism and cellular senescence
CD Wiley, J Campisi
Cell metabolism 23 (6), 1013-1021, 2016
3592016
The metabolic roots of senescence: mechanisms and opportunities for intervention
CD Wiley, J Campisi
Nature Metabolism 3 (10), 1290-1301, 2021
2662021
Alpha-ketoglutarate, an endogenous metabolite, extends lifespan and compresses morbidity in aging mice
AA Shahmirzadi, D Edgar, CY Liao, YM Hsu, M Lucanic, AA Shahmirzadi, ...
Cell metabolism 32 (3), 447-456. e6, 2020
2372020
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages
AJ Covarrubias, A Kale, R Perrone, JA Lopez-Dominguez, AO Pisco, ...
Nature metabolism 2 (11), 1265-1283, 2020
2332020
Analysis of individual cells identifies cell‐to‐cell variability following induction of cellular senescence
CD Wiley, JM Flynn, C Morrissey, R Lebofsky, J Shuga, X Dong, ...
Aging cell 16 (5), 1043-1050, 2017
2192017
Context-dependent effects of cellular senescence in cancer development
P Lecot, F Alimirah, PY Desprez, J Campisi, C Wiley
British journal of cancer 114 (11), 1180-1184, 2016
1842016
Systemic clearance of p16INK4a‐positive senescent cells mitigates age‐associated intervertebral disc degeneration
P Patil, Q Dong, D Wang, J Chang, C Wiley, M Demaria, J Lee, J Kang, ...
Aging cell 18 (3), e12927, 2019
1392019
Melanism in Peromyscus Is Caused by Independent Mutations in Agouti
EP Kingsley, M Manceau, CD Wiley, HE Hoekstra
PloS one 4 (7), e6435, 2009
1352009
Apigenin suppresses the senescence-associated secretory phenotype and paracrine effects on breast cancer cells
KM Perrott, CD Wiley, PY Desprez, J Campisi
Geroscience 39, 161-173, 2017
1262017
Disease drivers of aging
RJ Hodes, F Sierra, SN Austad, E Epel, GN Neigh, KM Erlandson, ...
Annals of the New York Academy of Sciences 1386 (1), 45-68, 2016
1242016
SILAC analysis reveals increased secretion of hemostasis-related factors by senescent cells
CD Wiley, S Liu, C Limbad, AM Zawadzka, J Beck, M Demaria, R Artwood, ...
Cell reports 28 (13), 3329-3337. e5, 2019
1172019
Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype
CD Wiley, N Schaum, F Alimirah, JA Lopez-Dominguez, AV Orjalo, ...
Scientific reports 8 (1), 2410, 2018
1112018
Impaired placental trophoblast lineage differentiation in Alkbh1−/− mice
Z Pan, S Sikandar, M Witherspoon, D Dizon, T Nguyen, K Benirschke, ...
Developmental dynamics 237 (2), 316-327, 2008
962008
Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis
CD Wiley, R Sharma, SS Davis, JA Lopez-Dominguez, KP Mitchell, ...
Cell metabolism 33 (6), 1124-1136. e5, 2021
902021
Secretion of leukotrienes by senescent lung fibroblasts promotes pulmonary fibrosis
CD Wiley, AN Brumwell, SS Davis, JR Jackson, A Valdovinos, C Calhoun, ...
JCI insight 4 (24), 2019
852019
Cellular senescence promotes skin carcinogenesis through p38MAPK and p44/42MAPK signaling
F Alimirah, T Pulido, A Valdovinos, S Alptekin, E Chang, E Jones, DA Diaz, ...
Cancer research 80 (17), 3606-3619, 2020
812020
Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin
DE Kim, MET Dollé, WP Vermeij, A Gyenis, K Vogel, JHJ Hoeijmakers, ...
Aging Cell 19 (3), e13072, 2020
502020
Peromyscus (deer mice) as developmental models
PB Vrana, KR Shorter, G Szalai, MR Felder, JP Crossland, M Veres, ...
Wiley Interdisciplinary Reviews: Developmental Biology 3 (3), 211-230, 2014
272014
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