| CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites Y Naito, K Hino, H Bono, K Ui-Tei Bioinformatics 31 (7), 1120-1123, 2015 | 1151 | 2015 |
| Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference K Ui‐Tei, Y Naito, F Takahashi, T Haraguchi, H Ohki‐Hamazaki, A Juni, ... Nucleic acids research 32 (3), 936-948, 2004 | 1092 | 2004 |
| siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference Y Naito, T Yamada, K Ui-Tei, S Morishita, K Saigo Nucleic acids research 32 (suppl_2), W124-W129, 2004 | 359 | 2004 |
| Polynucleotides for causing RNA interference and method for inhibiting gene expression using the same Y Naito, M Fujino, S Oguchi, Y Natori US Patent App. 11/598,052, 2008 | 358 | 2008 |
| siDirect 2.0: updated software for designing functional siRNA with reduced seed-dependent off-target effect Y Naito, J Yoshimura, S Morishita, K Ui-Tei BMC bioinformatics 10, 1-8, 2009 | 236 | 2009 |
| Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly … K Ui-Tei, Y Naito, S Zenno, K Nishi, K Yamato, F Takahashi, A Juni, ... Nucleic acids research 36 (7), 2136-2151, 2008 | 229 | 2008 |
| dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference Y Naito, T Yamada, T Matsumiya, K Ui-Tei, K Saigo, S Morishita Nucleic acids research 33 (suppl_2), W589-W591, 2005 | 217 | 2005 |
| Thermodynamic stability and Watson–Crick base pairing in the seed duplex are major determinants of the efficiency of the siRNA-based off-target effect K Ui-Tei, Y Naito, K Nishi, A Juni, K Saigo Nucleic acids research 36 (22), 7100-7109, 2008 | 199 | 2008 |
| CRISPR-Cas3 induces broad and unidirectional genome editing in human cells H Morisaka, K Yoshimi, Y Okuzaki, P Gee, Y Kunihiro, E Sonpho, H Xu, ... Nature communications 10 (1), 5302, 2019 | 166 | 2019 |
| siRNA design software for a target gene-specific RNA interference Y Naito, K Ui-Tei Frontiers in genetics 3, 102, 2012 | 89 | 2012 |
| Polynucleotides for causing RNA interference and method for inhibiting gene expression using the same Y Naito, M Fujino, S Oguchi, Y Natori US Patent App. 12/662,904, 2011 | 73 | 2011 |
| Optimal design and validation of antiviral siRNA for targeting HIV-1 Y Naito, K Nohtomi, T Onogi, R Uenishi, K Ui-Tei, K Saigo, Y Takebe Retrovirology 4, 1-5, 2007 | 68 | 2007 |
| Evaluation of off‐target effects of gapmer antisense oligonucleotides using human cells T Yoshida, Y Naito, H Yasuhara, K Sasaki, H Kawaji, J Kawai, M Naito, ... Genes to Cells 24 (12), 827-835, 2019 | 64 | 2019 |
| siVirus: web-based antiviral siRNA design software for highly divergent viral sequences Y Naito, K Ui-Tei, T Nishikawa, Y Takebe, K Saigo Nucleic acids research 34 (suppl_2), W448-W450, 2006 | 59 | 2006 |
| Designing functional siRNA with reduced off-target effects Y Naito, K Ui-Tei siRNA Design: Methods and Protocols, 57-68, 2013 | 53 | 2013 |
| E-cadherin is transcriptionally activated via suppression of ZEB1 transcriptional repressor by small RNA-mediated gene silencing M Mazda, K Nishi, Y Naito, K Ui-Tei PloS one 6 (12), e28688, 2011 | 48 | 2011 |
| Estimated number of off‐target candidate sites for antisense oligonucleotides in human mRNA sequences T Yoshida, Y Naito, K Sasaki, E Uchida, Y Sato, M Naito, T Kawanishi, ... Genes to Cells 23 (6), 448-455, 2018 | 40 | 2018 |
| Guidelines for the selection of effective short-interfering RNA sequences for functional genomics K Ui-Tei, Y Naito, K Saigo Target Discovery and Validation Reviews and Protocols: Volume 2: Emerging …, 2007 | 35 | 2007 |
| Technical considerations in Hi‐C scaffolding and evaluation of chromosome‐scale genome assemblies K Yamaguchi, M Kadota, O Nishimura, Y Ohishi, Y Naito, S Kuraku Molecular Ecology 30 (23), 5923-5934, 2021 | 29 | 2021 |
| Essential notes regarding the design of functional siRNAs for efficient mammalian RNAi K Ui-Tei, Y Naito, K Saigo BioMed Research International 2006 (1), 065052, 2006 | 25 | 2006 |
Hidemasa BonoGraduate School of Integrated Sciences for Life, Hiroshima UniversityVerified email at hiroshima-u.ac.jp
