Click and release: bioorthogonal approaches to “on-demand” activation of prodrugs X Ji, Z Pan, B Yu, LK De La Cruz, Y Zheng, B Ke, B Wang Chemical Society Reviews 48 (4), 1077-1094, 2019 | 275 | 2019 |
Enrichment-triggered prodrug activation demonstrated through mitochondria-targeted delivery of doxorubicin and carbon monoxide Y Zheng, X Ji, B Yu, K Ji, D Gallo, E Csizmadia, M Zhu, MR Choudhury, ... Nature chemistry 10 (7), 787-794, 2018 | 272 | 2018 |
Esterase‐sensitive prodrugs with tunable release rates and direct generation of hydrogen sulfide Y Zheng, B Yu, K Ji, Z Pan, V Chittavong, B Wang Angewandte Chemie International Edition 55 (14), 4514-4518, 2016 | 191 | 2016 |
Toward hydrogen sulfide based therapeutics: critical drug delivery and developability issues Y Zheng, B Yu, LK De La Cruz, M Roy Choudhury, A Anifowose, B Wang Medicinal Research Reviews 38 (1), 57-100, 2018 | 186 | 2018 |
Toward carbon monoxide–based therapeutics: Critical drug delivery and developability issues X Ji, K Damera, Y Zheng, B Yu, LE Otterbein, B Wang Journal of pharmaceutical sciences 105 (2), 406-416, 2016 | 177 | 2016 |
Hydrogen sulfide prodrugs—a review Y Zheng, X Ji, K Ji, B Wang Acta Pharmaceutica Sinica B 5 (5), 367-377, 2015 | 134 | 2015 |
A click-and-release approach to CO prodrugs D Wang, E Viennois, K Ji, K Damera, A Draganov, Y Zheng, C Dai, ... Chemical communications 50 (100), 15890-15893, 2014 | 128 | 2014 |
Highly Enantioselective Henry Reactions in Water Catalyzed by a Copper Tertiary Amine Complex and Applied in the Synthesis of (S)‐N‐trans‐Feruloyl … G Lai, F Guo, Y Zheng, Y Fang, H Song, K Xu, S Wang, Z Zha, Z Wang Chemistry–A European Journal 4 (17), 1114-1117, 2011 | 111 | 2011 |
An esterase‐sensitive prodrug approach for controllable delivery of persulfide species Y Zheng, B Yu, Z Li, Z Yuan, CL Organ, RK Trivedi, S Wang, DJ Lefer, ... Angewandte Chemie 129 (39), 11911-11915, 2017 | 100 | 2017 |
Toward direct protein S-persulfidation: a prodrug approach that directly delivers hydrogen persulfide B Yu, Y Zheng, Z Yuan, S Li, H Zhu, LK De La Cruz, J Zhang, K Ji, S Wang, ... Journal of the American Chemical Society 140 (1), 30-33, 2018 | 89 | 2018 |
3, 6-Substituted-1, 2, 4, 5-tetrazines: tuning reaction rates for staged labeling applications D Wang, W Chen, Y Zheng, C Dai, K Wang, B Ke, B Wang Organic & biomolecular chemistry 12 (23), 3950-3955, 2014 | 86 | 2014 |
Light-triggered release of conventional local anesthetics from a macromolecular prodrug for on-demand local anesthesia W Zhang, T Ji, Y Li, Y Zheng, M Mehta, C Zhao, A Liu, DS Kohane Nature communications 11 (1), 2323, 2020 | 59 | 2020 |
Esterase-sensitive glutathione persulfide donor Z Yuan, Y Zheng, B Yu, S Wang, X Yang, B Wang Organic letters 20 (20), 6364-6367, 2018 | 51 | 2018 |
Aromatized liposomes for sustained drug delivery Y Li, T Ji, M Torre, R Shao, Y Zheng, D Wang, X Li, A Liu, W Zhang, ... Nature communications 14 (1), 6659, 2023 | 43 | 2023 |
Post-synthesis DNA modifications using a trans-cyclooctene click handle K Wang, D Wang, K Ji, W Chen, Y Zheng, C Dai, B Wang Organic & biomolecular chemistry 13 (3), 909-915, 2015 | 43 | 2015 |
Biomarker-based metabolic labeling for redirected and enhanced immune response S Li, B Yu, J Wang, Y Zheng, H Zhang, MJ Walker, Z Yuan, H Zhu, ... ACS Chemical Biology 13 (6), 1686-1694, 2018 | 35 | 2018 |
Direct base‐assisted C–N bond formation between aryl halides and aliphatic tertiary amines under transition‐metal‐free conditions Y Fang, Y Zheng, Z Wang European Journal of Organic Chemistry 2012 (8), 1495-1498, 2012 | 29 | 2012 |
Prodrugs of hydrogen sulfide and related sulfur species: recent development Y Zheng-Nan, YQ Zheng, W Bing-He Chinese journal of natural medicines 18 (4), 296-307, 2020 | 25 | 2020 |
A general and efficient entry to asymmetric tetrazines for click chemistry applications D Wang, W Chen, Y Zheng, C Dai, L Wang, B Wang Heterocyclic Communications 19 (3), 171-177, 2013 | 25 | 2013 |
Functionalized multiarmed polycaprolactones as biocompatible tissue adhesives W Zhang, T Ji, S Lyon, M Mehta, Y Zheng, X Deng, A Liu, A Shagan, ... ACS applied materials & interfaces 12 (15), 17314-17320, 2020 | 24 | 2020 |