Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls 1958 Birth Cohort Controls Jones Richard W. 18 McArdle Wendy L. 18 Ring ... Nature 447 (7145), 661-678, 2007 | 9468 | 2007 |
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity TM Frayling, NJ Timpson, MN Weedon, E Zeggini, RM Freathy, ... Science 316 (5826), 889, 2007 | 5724 | 2007 |
The MR-Base platform supports systematic causal inference across the human phenome G Hemani, J Zheng, B Elsworth, KH Wade, V Haberland, D Baird, ... elife 7, e34408, 2018 | 5144 | 2018 |
Mendelian randomization: using genes as instruments for making causal inferences in epidemiology DA Lawlor, RM Harbord, JAC Sterne, N Timpson, G Davey Smith Statistics in Medicine 27 (8), 1133-1163, 2008 | 3659 | 2008 |
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index EK Speliotes, CJ Willer, SI Berndt, KL Monda, G Thorleifsson, AU Jackson, ... Nature genetics 42 (11), 937-948, 2010 | 3597 | 2010 |
A reference panel of 64,976 haplotypes for genotype imputation Nature genetics 48 (10), 1279-1283, 2016 | 3028 | 2016 |
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes E Zeggini, MN Weedon, CM Lindgren, TM Frayling, KS Elliott, H Lango, ... Science 316 (5829), 1336, 2007 | 2630 | 2007 |
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, ... Nature genetics 42 (2), 105-116, 2010 | 2570 | 2010 |
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes E Zeggini, LJ Scott, R Saxena, BF Voight, JL Marchini, T Hu, ... Nature genetics 40 (5), 638-645, 2008 | 2310 | 2008 |
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation Nature genetics 41 (1), 25-34, 2009 | 2092 | 2009 |
Newly identified loci that influence lipid concentrations and risk of coronary artery disease CJ Willer, S Sanna, AU Jackson, A Scuteri, LL Bonnycastle, R Clarke, ... Nature genetics 40 (2), 161-169, 2008 | 1947 | 2008 |
Common variants near MC4R are associated with fat mass, weight and risk of obesity RJF Loos, CM Lindgren, S Li, E Wheeler, JH Zhao, I Prokopenko, ... Nature genetics 40 (6), 768-775, 2008 | 1589 | 2008 |
Strengthening the reporting of observational studies in epidemiology using Mendelian randomization: the STROBE-MR statement VW Skrivankova, RC Richmond, BAR Woolf, J Yarmolinsky, NM Davies, ... Jama 326 (16), 1614-1621, 2021 | 1581 | 2021 |
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants 1958 Birth Cohort Controls: Jones Richard W 18 McArdle Wendy L 18 Ring Susan ... Nature genetics 39 (11), 1329-1337, 2007 | 1444 | 2007 |
Genome-wide association study identifies 74 loci associated with educational attainment A Okbay, JP Beauchamp, MA Fontana, JJ Lee, TH Pers, CA Rietveld, ... Nature 533 (7604), 539-542, 2016 | 1433 | 2016 |
Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors S Burgess, RA Scott, NJ Timpson, G Davey Smith, SG Thompson, ... European journal of epidemiology 30, 543-552, 2015 | 1149 | 2015 |
Large-scale association analyses identify host factors influencing human gut microbiome composition A Kurilshikov, C Medina-Gomez, R Bacigalupe, D Radjabzadeh, J Wang, ... Nature genetics 53 (2), 156-165, 2021 | 1123 | 2021 |
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses A Okbay, BML Baselmans, JE De Neve, P Turley, MG Nivard, MA Fontana, ... Nature genetics 48 (6), 624-633, 2016 | 1119 | 2016 |
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution IM Heid, AU Jackson, JC Randall, TW Winkler, L Qi, V Steinthorsdottir, ... Nature genetics 42 (11), 949-960, 2010 | 1119 | 2010 |
The UK10K project identifies rare variants in health and disease Statistics group Ciampi Antonio 8 Greenwood Celia MT (co-chair) 7 8 14 19 ... Nature 526 (7571), 82-90, 2015 | 1109 | 2015 |