Redox-based reagents for chemoselective methionine bioconjugation S Lin, X Yang, S Jia, AM Weeks, M Hornsby, PS Lee, RV Nichiporuk, ... Science 355 (6325), 597-602, 2017 | 428 | 2017 |
Palladium-triggered deprotection chemistry for protein activation in living cells J Li, J Yu, J Zhao, J Wang, S Zheng, S Lin, L Chen, M Yang, S Jia, ... Nature chemistry 6 (4), 352-361, 2014 | 392 | 2014 |
A genetically incorporated crosslinker reveals chaperone cooperation in acid resistance M Zhang, S Lin, X Song, J Liu, Y Fu, X Ge, X Fu, Z Chang, PR Chen Nature chemical biology 7 (10), 671-677, 2011 | 243 | 2011 |
Ligand-free palladium-mediated site-specific protein labeling inside gram-negative bacterial pathogens J Li, S Lin, J Wang, S Jia, M Yang, Z Hao, X Zhang, PR Chen Journal of the American Chemical Society 135 (19), 7330-7338, 2013 | 181 | 2013 |
Converting a solvatochromic fluorophore into a protein-based pH indicator for extreme acidity. M Yang, Y Song, M Zhang, S Lin, Z Hao, Y Liang, D Zhang, PR Chen Angewandte Chemie (International ed. in English) 51 (31), 7674-7679, 2012 | 125 | 2012 |
Site-specific incorporation of photo-cross-linker and bioorthogonal amino acids into enteric bacterial pathogens S Lin, Z Zhang, H Xu, L Li, S Chen, J Li, Z Hao, PR Chen Journal of the American chemical society 133 (50), 20581-20587, 2011 | 87 | 2011 |
Genetically encoded protein photocrosslinker with a transferable mass spectrometry-identifiable label Y Yang, H Song, D He, S Zhang, S Dai, S Lin, R Meng, C Wang, PR Chen Nature Communications 7 (1), 12299, 2016 | 85 | 2016 |
Site-specific engineering of chemical functionalities on the surface of live hepatitis D virus. S Lin, H Yan, L Li, M Yang, B Peng, S Chen, W Li, PR Chen Angewandte Chemie 125 (52), 2013 | 68 | 2013 |
Acetylation-dependent deubiquitinase OTUD3 controls MAVS activation in innate antiviral immunity Z Zhang, X Fang, X Wu, L Ling, F Chu, J Li, S Wang, J Zang, B Zhang, ... Molecular cell 79 (2), 304-319. e7, 2020 | 59 | 2020 |
Genetically encoded cleavable protein photo-cross-linker S Lin, D He, T Long, S Zhang, R Meng, PR Chen Journal of the American Chemical Society 136 (34), 11860-11863, 2014 | 58 | 2014 |
Mechanism-based design of a photoactivatable firefly luciferase J Zhao, S Lin, Y Huang, J Zhao, PR Chen Journal of the American Chemical Society 135 (20), 7410-7413, 2013 | 57 | 2013 |
A readily synthesized cyclic pyrrolysine analogue for site-specific protein “click” labeling Z Hao, Y Song, S Lin, M Yang, Y Liang, J Wang, PR Chen Chemical communications 47 (15), 4502-4504, 2011 | 57 | 2011 |
Chimeric design of pyrrolysyl-tRNA synthetase/tRNA pairs and canonical synthetase/tRNA pairs for genetic code expansion W Ding, H Zhao, Y Chen, B Zhang, Y Yang, J Zang, J Wu, S Lin Nature Communications 11 (1), 3154, 2020 | 45 | 2020 |
Comparative proteomics reveal distinct chaperone–client interactions in supporting bacterial acid resistance S Zhang, D He, Y Yang, S Lin, M Zhang, S Dai, PR Chen Proceedings of the National Academy of Sciences 113 (39), 10872-10877, 2016 | 36 | 2016 |
Reversible phosphorylation of Rpn1 regulates 26S proteasome assembly and function X Liu, W Xiao, Y Zhang, SE Wiley, T Zuo, Y Zheng, N Chen, L Chen, ... Proceedings of the National Academy of Sciences 117 (1), 328-336, 2020 | 35 | 2020 |
Genetically encoded releasable photo-cross-linking strategies for studying protein–protein interactions in living cells Y Yang, H Song, D He, S Zhang, S Dai, X Xie, S Lin, Z Hao, H Zheng, ... Nature protocols 12 (10), 2147-2168, 2017 | 33 | 2017 |
Chemoselective methionine bioconjugation on a polypeptide, protein, and proteome J Zang, Y Chen, W Zhu, S Lin Biochemistry 59 (2), 132-138, 2019 | 29 | 2019 |
Histone H2A phosphorylation recruits topoisomerase II α to centromeres to safeguard genomic stability M Zhang, C Liang, Q Chen, H Yan, J Xu, H Zhao, X Yuan, J Liu, S Lin, ... The EMBO Journal 39 (3), e101863, 2020 | 28 | 2020 |
Deactylation by SIRT1 enables liquid–liquid phase separation of IRF3/IRF7 in innate antiviral immunity Z Qin, X Fang, W Sun, Z Ma, T Dai, S Wang, Z Zong, H Huang, H Ru, H Lu, ... Nature Immunology 23 (8), 1193-1207, 2022 | 25 | 2022 |
Directed-evolution of translation system for efficient unnatural amino acids incorporation and generalizable synthetic auxotroph construction H Zhao, W Ding, J Zang, Y Yang, C Liu, L Hu, Y Chen, G Liu, Y Fang, ... Nature Communications 12 (1), 7039, 2021 | 23 | 2021 |