|Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA|
D Mashiko, Y Fujihara, Y Satouh, H Miyata, A Isotani, M Ikawa
Scientific reports 3, 3355, 2013
|Sperm calcineurin inhibition prevents mouse fertility with implications for male contraceptive|
H Miyata, Y Satouh, D Mashiko, M Muto, K Nozawa, K Shiba, Y Fujihara, ...
Science 350 (6259), 442-445, 2015
|Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice|
H Miyata, JM Castaneda, Y Fujihara, Z Yu, DR Archambeault, A Isotani, ...
Proceedings of the National Academy of Sciences 113 (28), 7704-7710, 2016
|Behavior of mouse spermatozoa in the female reproductive tract from soon after mating to the beginning of fertilization|
Y Muro, H Hasuwa, A Isotani, H Miyata, K Yamagata, M Ikawa, ...
Biology of Reproduction 94 (4), 80, 1-7, 2016
|CRISPR/Cas9 mediated genome editing in ES cells and its application for chimeric analysis in mice|
A Oji, T Noda, Y Fujihara, H Miyata, YJ Kim, M Muto, K Nozawa, ...
Scientific reports 6 (1), 1-9, 2016
|A role of TMEM16E carrying a scrambling domain in sperm motility|
S Gyobu, H Miyata, M Ikawa, D Yamazaki, H Takeshima, J Suzuki, ...
Molecular and cellular biology 36 (4), 645-659, 2016
|TCTE1 is a conserved component of the dynein regulatory complex and is required for motility and metabolism in mouse spermatozoa|
JM Castaneda, R Hua, H Miyata, A Oji, Y Guo, Y Cheng, T Zhou, X Guo, ...
Proceedings of the National Academy of Sciences 114 (27), E5370-E5378, 2017
|CRISPR/Cas9-mediated rapid generation of multiple mouse lines identified Ccdc63 as essential for spermiogenesis|
SAM Young, H Miyata, Y Satouh, H Kato, K Nozawa, A Isotani, RJ Aitken, ...
International journal of molecular sciences 16 (10), 24732-24750, 2015
|RSPH6A is required for sperm flagellum formation and male fertility in mice|
F Abbasi, H Miyata, K Shimada, A Morohoshi, K Nozawa, T Matsumura, ...
Journal of cell science 131 (19), 2018
|Fertilization defects in sperm from Cysteine-rich secretory protein 2 (Crisp2) knockout mice: implications for fertility disorders|
NG Brukman, H Miyata, P Torres, D Lombardo, JJ Caramelo, M Ikawa, ...
Molecular human reproduction 22 (4), 240-251, 2016
|Protease activation and the signal transduction pathway regulating motility in sperm from the water strider Aquarius remigis|
H Miyata, CD Thaler, LT Haimo, RA Cardullo
Cytoskeleton 69 (4), 207-220, 2012
|The Mg2+ transporter CNNM4 regulates sperm Ca2+ homeostasis and is essential for reproduction|
D Yamazaki, H Miyata, Y Funato, Y Fujihara, M Ikawa, H Miki
Journal of Cell Science 129 (9), 1940-1949, 2016
|CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice|
Y Lu, S Oura, T Matsumura, A Oji, N Sakurai, Y Fujihara, K Shimada, ...
Biology of reproduction 101 (2), 501-511, 2019
|Revolutionizing male fertility factor research in mice by using the genome editing tool CRISPR/Cas9|
F Abbasi, H Miyata, M Ikawa
Reproductive medicine and biology 17 (1), 3-10, 2018
|Factors controlling sperm migration through the oviduct revealed by gene-modified mouse models|
Y Fujihara, H Miyata, M Ikawa
Experimental animals, 17-0153, 2018
|CABYR is essential for fibrous sheath integrity and progressive motility in mouse spermatozoa|
SAM Young, H Miyata, Y Satouh, RJ Aitken, MA Baker, M Ikawa
Journal of cell science 129 (23), 4379-4387, 2016
|The Rab11-binding protein RELCH/KIAA1468 controls intracellular cholesterol distribution|
T Sobajima, S Yoshimura, T Maeda, H Miyata, E Miyoshi, A Harada
The Journal of cell biology 217 (5), 1777-1796, 2018
|CRISPR/Cas9-mediated mutation revealed cytoplasmic tail is dispensable for IZUMO1 function and male fertility|
SAM Young, H Miyata, Y Satouh, M Muto, MR Larsen, RJ Aitken, ...
Reproduction 152 (6), 665-672, 2016
|Immunomodulatory drugs inhibit TLR4-induced type-1 interferon production independently of Cereblon via suppression of the TRIF/IRF3 pathway|
D Millrine, H Miyata, M Tei, P Dubey, K Nyati, T Nakahama, Y Gemechu, ...
International immunology 28 (6), 307-315, 2016
|A novel transcriptional factor Nkapl is a germ cell-specific suppressor of Notch signaling and is indispensable for spermatogenesis|
H Okuda, H Kiuchi, T Takao, Y Miyagawa, A Tsujimura, N Nonomura, ...
PloS One 10 (4), e0124293, 2015