High sensitivity mapping of methylated cytosines JCI Susan, J Harrison, CL Paul, M Frommer Nucleic acids research 22 (15), 2990-2997, 1994 | 2351 | 1994 |
Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling R Pidsley, E Zotenko, TJ Peters, MG Lawrence, GP Risbridger, P Molloy, ... Genome biology 17, 1-17, 2016 | 1249 | 2016 |
miRNA‐dependent gene silencing involving Ago2‐mediated cleavage of a circular antisense RNA TB Hansen, ED Wiklund, JB Bramsen, SB Villadsen, AL Statham, SJ Clark, ... The EMBO journal 30 (21), 4414-4422, 2011 | 1065 | 2011 |
Bisulfite genomic sequencing: systematic investigation of critical experimental parameters C Grunau, SJ Clark, A Rosenthal Nucleic acids research 29 (13), e65-e65, 2001 | 1030 | 2001 |
De novo identification of differentially methylated regions in the human genome TJ Peters, MJ Buckley, AL Statham, R Pidsley, K Samaras, R V Lord, ... Epigenetics & chromatin 8, 1-16, 2015 | 831 | 2015 |
Methyl-CpG-binding domain proteins: readers of the epigenome Q Du, PL Luu, C Stirzaker, SJ Clark Epigenomics 7 (6), 1051-1073, 2015 | 502 | 2015 |
Detection and measurement of PCR bias in quantitative methylation analysis of bisulphite-treated DNA PM Warnecke, C Stirzaker, JR Melki, DS Millar, CL Paul, SJ Clark Nucleic acids research 25 (21), 4422-4426, 1997 | 481 | 1997 |
Epigenetics and human obesity SJ Van Dijk, PL Molloy, H Varinli, JL Morrison, BS Muhlhausler International journal of obesity 39 (1), 85-97, 2015 | 458 | 2015 |
Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band J Frigola, J Song, C Stirzaker, RA Hinshelwood, MA Peinado, SJ Clark Nature genetics 38 (5), 540-549, 2006 | 458 | 2006 |
Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia JR Melki, PC Vincent, SJ Clark Cancer research 59 (15), 3730-3740, 1999 | 458 | 1999 |
Coordinated epigenetic repression of the miR‐200 family and miR‐205 in invasive bladder cancer ED Wiklund, JB Bramsen, T Hulf, L Dyrskjøt, R Ramanathan, TB Hansen, ... International journal of cancer 128 (6), 1327-1334, 2011 | 442 | 2011 |
DNA methylation: bisulphite modification and analysis SJ Clark, A Statham, C Stirzaker, PL Molloy, M Frommer Nature protocols 1 (5), 2353-2364, 2006 | 428 | 2006 |
DNA methylation and gene silencing in cancer: which is the guilty party? SJ Clark, J Melki Oncogene 21 (35), 5380-5387, 2002 | 400 | 2002 |
Identification and resolution of artifacts in bisulfite sequencing PM Warnecke, C Stirzaker, J Song, C Grunau, JR Melki, SJ Clark Methods 27 (2), 101-107, 2002 | 398 | 2002 |
Extensive DNA Methylation Spanning the Rb Promoter in Retinoblastoma Tumors C Stirzaker, DS Millar, CL Paul, PM Warnecke, J Harrison, PC Vincent, ... Cancer research 57 (11), 2229-2237, 1997 | 393 | 1997 |
Three-dimensional disorganization of the cancer genome occurs coincident with long-range genetic and epigenetic alterations PC Taberlay, J Achinger-Kawecka, ATL Lun, FA Buske, K Sabir, ... Genome research 26 (6), 719-731, 2016 | 356 | 2016 |
CpNpG methylation in mammalian cells SJ Clark, J Harrison, M Frommer Nature genetics 10 (1), 20-27, 1995 | 350 | 1995 |
Detailed methylation analysis of the glutathione S-transferase π (GSTP1) gene in prostate cancer DS Millar, KK Ow, CL Paul, PJ Russell, PL Molloy, SJ Clark Oncogene 18 (6), 1313-1324, 1999 | 306 | 1999 |
Sp1 binding is inhibited by mCpmCpG methylation SJ Clark, J Harrison, PL Molloy Gene 195 (1), 67-71, 1997 | 279 | 1997 |
Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells C Stirzaker, JZ Song, B Davidson, SJ Clark Cancer research 64 (11), 3871-3877, 2004 | 277 | 2004 |