Intravenous administration of the adeno-associated virus-PHP. B capsid fails to upregulate transduction efficiency in the marmoset brain Y Matsuzaki, A Konno, R Mochizuki, Y Shinohara, K Nitta, Y Okada, ... Neuroscience letters 665, 182-188, 2018 | 145 | 2018 |
Kv3. 3 channels harbouring a mutation of spinocerebellar ataxia type 13 alter excitability and induce cell death in cultured cerebellar Purkinje cells T Irie, Y Matsuzaki, Y Sekino, H Hirai The Journal of physiology 592 (1), 229-247, 2014 | 60 | 2014 |
Distinct transduction profiles in the CNS via three injection routes of AAV9 and the application to generation of a neurodegenerative mouse model F Huda, A Konno, Y Matsuzaki, H Goenawan, K Miyake, T Shimada, ... Molecular Therapy-Methods & Clinical Development 1, 2014 | 58 | 2014 |
Neurotropic properties of AAV-PHP. B are shared among diverse inbred strains of mice Y Matsuzaki, M Tanaka, S Hakoda, T Masuda, R Miyata, A Konno, H Hirai Molecular Therapy 27 (4), 700-704, 2019 | 51 | 2019 |
Minimal Purkinje cell-specific PCP2/L7 promoter virally available for rodents and non-human primates K Nitta, Y Matsuzaki, A Konno, H Hirai Molecular Therapy-Methods & Clinical Development 6, 159-170, 2017 | 49 | 2017 |
Shp2 in forebrain neurons regulates synaptic plasticity, locomotion, and memory formation in mice S Kusakari, F Saitow, Y Ago, K Shibasaki, M Sato-Hashimoto, ... Molecular and cellular biology, 2015 | 34 | 2015 |
Generation of a neurodegenerative disease mouse model using lentiviral vectors carrying an enhanced synapsin I promoter Y Matsuzaki, M Oue, H Hirai Journal of neuroscience methods 223, 133-143, 2014 | 30 | 2014 |
Transduction profile of the marmoset central nervous system using adeno-associated virus serotype 9 vectors Y Matsuzaki, A Konno, R Mukai, F Honda, M Hirato, Y Yoshimoto, H Hirai Molecular neurobiology 54, 1745-1758, 2017 | 26 | 2017 |
Effects of neutralizing antibody production on AAV-PHP. B-mediated transduction of the mouse central nervous system Y Shinohara, A Konno, K Nitta, Y Matsuzaki, H Yasui, J Suwa, K Hiromura, ... Molecular neurobiology 56, 4203-4214, 2019 | 25 | 2019 |
Fusion of human fetal mesenchymal stem cells with “degenerating” cerebellar neurons in spinocerebellar ataxia type 1 model mice F Huda, Y Fan, M Suzuki, A Konno, Y Matsuzaki, N Takahashi, JKY Chan, ... PloS one 11 (11), e0164202, 2016 | 24 | 2016 |
Viral vector-based dissection of marmoset GFAP promoter in mouse and marmoset brains Y Shinohara, A Konno, N Takahashi, Y Matsuzaki, S Kishi, H Hirai PLoS One 11 (8), e0162023, 2016 | 22 | 2016 |
Comparative study of neuron-specific promoters in mouse brain transduced by intravenously administered AAV-PHP. eB PT Radhiyanti, A Konno, Y Matsuzaki, H Hirai Neuroscience letters 756, 135956, 2021 | 19 | 2021 |
Pharmacological enhancement of retinoid-related orphan receptor α function mitigates spinocerebellar ataxia type 3 pathology M Watanave, C Hoshino, A Konno, Y Fukuzaki, Y Matsuzaki, T Ishitani, ... Neurobiology of disease 121, 263-273, 2019 | 18 | 2019 |
Contribution of thyrotropin-releasing hormone to cerebellar long-term depression and motor learning M Watanave, Y Matsuzaki, Y Nakajima, A Ozawa, M Yamada, H Hirai Frontiers in cellular neuroscience 12, 490, 2018 | 15 | 2018 |
Development of microglia-targeting adeno-associated viral vectors as tools to study microglial behavior in vivo Y Okada, N Hosoi, Y Matsuzaki, Y Fukai, A Hiraga, J Nakai, K Nitta, ... Communications Biology 5 (1), 1224, 2022 | 13 | 2022 |
Global knockdown of retinoid-related orphan receptor α in mature purkinje cells reveals aberrant cerebellar phenotypes of spinocerebellar ataxia H Yasui, Y Matsuzaki, A Konno, H Hirai Neuroscience 462, 328-336, 2021 | 12 | 2021 |
Protein kinase Cγ in cerebellar Purkinje cells regulates Ca2+-activated large-conductance K+ channels and motor coordination M Watanave, N Takahashi, N Hosoi, A Konno, H Yamamoto, H Yasui, ... Proceedings of the National Academy of Sciences 119 (7), e2113336119, 2022 | 11 | 2022 |
Identification of a high incidence region for retroviral vector integration near exon 1 of the LMO2locus K Yamada, T Tsukahara, K Yoshino, K Kojima, H Agawa, Y Yamashita, ... Retrovirology 6, 1-9, 2009 | 11 | 2009 |
One-year follow-up of transgene expression by integrase-defective lentiviral vectors and their therapeutic potential in spinocerebellar ataxia model mice H Saida, Y Matsuzaki, K Takayama, A Iizuka, A Konno, S Yanagi, H Hirai Gene Therapy 21 (9), 820-827, 2014 | 10 | 2014 |
Plasticity of the developmentally arrested staggerer cerebellum in response to exogenous RORα A Iizuka, Y Matsuzaki, A Konno, H Hirai Brain Structure and Function 221, 2879-2889, 2016 | 9 | 2016 |