| Deciphering how naturally occurring sequence features impact the phase behaviours of disordered prion-like domains A Bremer, M Farag, WM Borcherds, I Peran, EW Martin, RV Pappu, ... Nature Chemistry 14 (2), 196-207, 2022 | 227 | 2022 |
| Disorder and residual helicity alter p53-Mdm2 binding affinity and signaling in cells W Borcherds, FX Theillet, A Katzer, A Finzel, KM Mishall, AT Powell, H Wu, ... Nature chemical biology 10 (12), 1000-1002, 2014 | 185 | 2014 |
| How do intrinsically disordered protein regions encode a driving force for liquid–liquid phase separation? W Borcherds, A Bremer, MB Borgia, T Mittag Current opinion in structural biology 67, 41-50, 2021 | 164 | 2021 |
| Interaction between p53 N terminus and core domain regulates specific and nonspecific DNA binding F He, W Borcherds, T Song, X Wei, M Das, L Chen, GW Daughdrill, ... Proceedings of the National Academy of Sciences 116 (18), 8859-8868, 2019 | 75 | 2019 |
| Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expanded conformations M Farag, SR Cohen, WM Borcherds, A Bremer, T Mittag, RV Pappu Nature communications 13 (1), 7722, 2022 | 60 | 2022 |
| α-Helix-mimicking sulfono-γ-AApeptide inhibitors for p53–MDM2/MDMX protein–protein interactions P Sang, Y Shi, J Lu, L Chen, L Yang, W Borcherds, S Abdulkadir, Q Li, ... Journal of medicinal chemistry 63 (3), 975-986, 2020 | 53 | 2020 |
| Autoinhibition of MDMX by intramolecular p53 mimicry L Chen, W Borcherds, S Wu, A Becker, E Schonbrunn, GW Daughdrill, ... Proceedings of the National Academy of Sciences 112 (15), 4624-4629, 2015 | 50 | 2015 |
| Conformational buffering underlies functional selection in intrinsically disordered protein regions NS Gonzalez-Foutel, J Glavina, WM Borcherds, M Safranchik, ... Nature structural & molecular biology 29 (8), 781-790, 2022 | 48 | 2022 |
| Secondary interaction between MDMX and p53 core domain inhibits p53 DNA binding X Wei, S Wu, T Song, L Chen, M Gao, W Borcherds, GW Daughdrill, ... Proceedings of the National Academy of Sciences 113 (19), E2558-E2563, 2016 | 47 | 2016 |
| Conserved helix-flanking prolines modulate intrinsically disordered protein: target affinity by altering the lifetime of the bound complex MD Crabtree, W Borcherds, A Poosapati, SL Shammas, GW Daughdrill, ... Biochemistry 56 (18), 2379-2384, 2017 | 46 | 2017 |
| Optimal affinity enhancement by a conserved flexible linker controls p53 mimicry in MdmX W Borcherds, A Becker, L Chen, J Chen, LB Chemes, GW Daughdrill Biophysical Journal 112 (10), 2038-2042, 2017 | 33 | 2017 |
| Phase separation of protein mixtures is driven by the interplay of homotypic and heterotypic interactions M Farag, WM Borcherds, A Bremer, T Mittag, RV Pappu Nature communications 14 (1), 5527, 2023 | 20 | 2023 |
| Uncoupling the folding and binding of an intrinsically disordered protein A Poosapati, E Gregory, WM Borcherds, LB Chemes, GW Daughdrill Journal of molecular biology 430 (16), 2389-2402, 2018 | 19 | 2018 |
| Conserved glycines control disorder and function in the cold-regulated protein, COR15A OT Sowemimo, P Knox-Brown, W Borcherds, T Rindfleisch, ... Biomolecules 9 (3), 84, 2019 | 17 | 2019 |
| Structural divergence is more extensive than sequence divergence for a family of intrinsically disordered proteins W Borcherds, S Kashtanov, H Wu, GW Daughdrill Proteins: Structure, Function, and Bioinformatics 81 (10), 1686-1698, 2013 | 17 | 2013 |
| Using NMR chemical shifts to determine residue-specific secondary structure populations for intrinsically disordered proteins WM Borcherds, GW Daughdrill Methods in enzymology 611, 101-136, 2018 | 15 | 2018 |
| Using chemical shifts to assess transient secondary structure and generate ensemble structures of intrinsically disordered proteins S Kashtanov, W Borcherds, H Wu, GW Daughdrill, FM Ytreberg Intrinsically Disordered Protein Analysis: Volume 1, Methods and …, 2012 | 15 | 2012 |
| Relationship between gene duplicability and diversifiability in the topology of biochemical networks Z Guo, W Jiang, N Lages, W Borcherds, D Wang BMC genomics 15, 1-12, 2014 | 14 | 2014 |
| Condensates of disordered proteins have small-world network structures and interfaces defined by expanded conformations M Farag, SR Cohen, WM Borcherds, A Bremer, T Mittag, RV Pappu bioRxiv, 2022.05. 21.492916, 2022 | 13 | 2022 |
| Using chemical shifts to generate structural ensembles for intrinsically disordered proteins with converged distributions of secondary structure FM Ytreberg, W Borcherds, H Wu, GW Daughdrill Biophysical Journal 108 (2), 227a-228a, 2015 | 13 | 2015 |
