フォロー
Alexander Loewer
Alexander Loewer
Professor, Technical University Darmstadt
確認したメール アドレス: mdc-berlin.de - ホームページ
タイトル
引用先
引用先
Circular RNAs are a large class of animal RNAs with regulatory potency
S Memczak, M Jens, A Elefsinioti, F Torti, J Krueger, A Rybak, L Maier, ...
Nature 495 (7441), 333-338, 2013
72262013
p53 dynamics control cell fate
JE Purvis, KW Karhohs, C Mock, E Batchelor, A Loewer, G Lahav
Science 336 (6087), 1440-1444, 2012
8612012
Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage
E Batchelor, CS Mock, I Bhan, A Loewer, G Lahav
Molecular cell 30 (3), 277-289, 2008
5082008
Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase
K Karanam, R Kafri, A Loewer, G Lahav
Molecular cell 47 (2), 320-329, 2012
4702012
Homo‐and heterodimerization of APP family members promotes intercellular adhesion
P Soba, S Eggert, K Wagner, H Zentgraf, K Siehl, S Kreger, A Löwer, ...
The EMBO journal 24 (20), 3624-3634, 2005
4092005
Stimulus‐dependent dynamics of p53 in single cells
E Batchelor, A Loewer, C Mock, G Lahav
Molecular systems biology 7 (1), 488, 2011
3912011
The ups and downs of p53: understanding protein dynamics in single cells
E Batchelor, A Loewer, G Lahav
Nature Reviews Cancer 9 (5), 371-377, 2009
3072009
Basal dynamics of p53 reveal transcriptionally attenuated pulses in cycling cells
A Loewer, E Batchelor, G Gaglia, G Lahav
Cell 142 (1), 89-100, 2010
2852010
Cell-to-cell variation in p53 dynamics leads to fractional killing
AL Paek, JC Liu, A Loewer, WC Forrester, G Lahav
Cell 165 (3), 631-642, 2016
2842016
Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction
JD Orth, A Loewer, G Lahav, TJ Mitchison
Molecular biology of the cell 23 (4), 567-576, 2012
2782012
Disorder and residual helicity alter p53-Mdm2 binding affinity and signaling in cells
W Borcherds, FX Theillet, A Katzer, A Finzel, KM Mishall, AT Powell, H Wu, ...
Nature chemical biology 10 (12), 1000-1002, 2014
1822014
Distinct mechanisms act in concert to mediate cell cycle arrest
JE Toettcher, A Loewer, GJ Ostheimer, MB Yaffe, B Tidor, G Lahav
Proceedings of the National Academy of Sciences 106 (3), 785-790, 2009
1312009
PIEZO2 is required for mechanotransduction in human stem cell–derived touch receptors
K Schrenk-Siemens, H Wende, V Prato, K Song, C Rostock, A Loewer, ...
Nature neuroscience 18 (1), 10-16, 2015
1152015
Interference of human and Drosophila APP and APP‐like proteins with PNS development in Drosophila
G Merdes, P Soba, A Loewer, MV Bilic, K Beyreuther, R Paro
The EMBO journal 23 (20), 4082-4095, 2004
982004
Differential protein occupancy profiling of the mRNA transcriptome
M Schueler, M Munschauer, LH Gregersen, A Finzel, A Loewer, W Chen, ...
Genome biology 15, 1-17, 2014
912014
The p53 response in single cells is linearly correlated to the number of DNA breaks without a distinct threshold
A Loewer, K Karanam, C Mock, G Lahav
BMC biology 11, 1-13, 2013
912013
We are all individuals: causes and consequences of non-genetic heterogeneity in mammalian cells
A Loewer, G Lahav
Current opinion in genetics & development 21 (6), 753-758, 2011
902011
Chlamydia infection depends on a functional MDM2-p53 axis
E González, M Rother, MC Kerr, MA Al-Zeer, M Abu-Lubad, M Kessler, ...
Nature communications 5 (1), 5201, 2014
862014
A synthetic–natural hybrid oscillator in human cells
JE Toettcher, C Mock, E Batchelor, A Loewer, G Lahav
Proceedings of the National Academy of Sciences 107 (39), 17047-17052, 2010
862010
Cell‐specific responses to the cytokine TGF β are determined by variability in protein levels
J Strasen, U Sarma, M Jentsch, S Bohn, C Sheng, D Horbelt, P Knaus, ...
Molecular systems biology 14 (1), e7733, 2018
632018
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論文 1–20