| Single-cell bioluminescence imaging of deep tissue in freely moving animals S Iwano, M Sugiyama, H Hama, A Watakabe, N Hasegawa, T Kuchimaru, ... Science 359 (6378), 935-939, 2018 | 386 | 2018 |
| A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging T Kuchimaru, S Iwano, M Kiyama, S Mitsumata, T Kadonosono, H Niwa, ... Nature communications 7 (1), 11856, 2016 | 224 | 2016 |
| Intracellular CO release from composite of ferritin and ruthenium carbonyl complexes K Fujita, Y Tanaka, T Sho, S Ozeki, S Abe, T Hikage, T Kuchimaru, ... Journal of the American Chemical Society 136 (48), 16902-16908, 2014 | 107 | 2014 |
| A reliable murine model of bone metastasis by injecting cancer cells through caudal arteries T Kuchimaru, N Kataoka, K Nakagawa, T Isozaki, H Miyabara, ... Nature communications 9 (1), 2981, 2018 | 101 | 2018 |
| Preparation of a cross-linked porous protein crystal containing Ru carbonyl complexes as a CO-releasing extracellular scaffold H Tabe, K Fujita, S Abe, M Tsujimoto, T Kuchimaru, S Kizaka-Kondoh, ... Inorganic Chemistry 54 (1), 215-220, 2015 | 82 | 2015 |
| Calcium phosphate microcrystals in the renal tubular fluid accelerate chronic kidney disease progression K Shiizaki, A Tsubouchi, Y Miura, K Seo, T Kuchimaru, H Hayashi, ... The Journal of clinical investigation 131 (16), 2021 | 62 | 2021 |
| Cell penetrating peptides improve tumor delivery of cargos through neuropilin-1-dependent extravasation T Kadonosono, A Yamano, T Goto, T Tsubaki, M Niibori, T Kuchimaru, ... Journal of Controlled Release 201, 14-21, 2015 | 61 | 2015 |
| MT1-MMP plays a critical role in hematopoiesis by regulating HIF-mediated chemokine/cytokine gene transcription within niche cells C Nishida, K Kusubata, Y Tashiro, I Gritli, A Sato, M Ohki-Koizumi, ... Blood, The Journal of the American Society of Hematology 119 (23), 5405-5416, 2012 | 59 | 2012 |
| A hypoxia-inducible factor (HIF)-3α splicing variant, HIF-3α4 impairs angiogenesis in hypervascular malignant meningiomas with epigenetically silenced HIF-3α4 H Ando, A Natsume, K Iwami, F Ohka, T Kuchimaru, S Kizaka-Kondoh, ... Biochemical and biophysical research communications 433 (1), 139-144, 2013 | 48 | 2013 |
| In vivo imaging of HIF-active tumors by an oxygen-dependent degradation protein probe with an interchangeable labeling system T Kuchimaru, T Kadonosono, S Tanaka, T Ushiki, M Hiraoka, ... PloS one 5 (12), e15736, 2010 | 38 | 2010 |
| The effect of triamcinolone acetonide on laser-induced choroidal neovascularization in mice using a hypoxia visualization bio-imaging probe S Takata, T Masuda, S Nakamura, T Kuchimaru, K Tsuruma, ... Scientific Reports 5 (1), 9898, 2015 | 26 | 2015 |
| Synthesis and Luminescence Properties of Near-Infrared N-Heterocyclic Luciferin Analogues for In Vivo Optical Imaging R Saito, T Kuchimaru, S Higashi, SW Lu, M Kiyama, S Iwano, R Obata, ... Bulletin of the Chemical Society of Japan 92 (3), 608-618, 2019 | 25 | 2019 |
| Synthesis and biological activity of furanylindazoles as inhibitors of hypoxia inducible factor (HIF)-1 transcriptional activity A Takeuchi, M Hori, S Sato, HS Ban, T Kuchimaru, S Kizaka-Kondoh, ... MedChemComm 3 (11), 1455-1461, 2012 | 25 | 2012 |
| Angular optimization for cancer identification with circularly polarized light N Nishizawa, B Al‐Qadi, T Kuchimaru Journal of Biophotonics 14 (3), e202000380, 2021 | 24 | 2021 |
| Monte Carlo simulation of scattered circularly polarized light in biological tissues for detection technique of abnormal tissues using spin-polarized light emitting diodes N Nishizawa, A Hamada, K Takahashi, T Kuchimaru, H Munekata Japanese Journal of Applied Physics 59 (SE), SEEG03, 2020 | 23 | 2020 |
| Design of a CO-releasing extracellular scaffold using in vivo protein crystals H Tabe, T Shimoi, K Fujita, S Abe, H Ijiri, M Tsujimoto, T Kuchimaru, ... Chemistry Letters 44 (3), 342-344, 2015 | 23 | 2015 |
| Pathophysiological response to hypoxia—from the molecular mechanisms of malady to drug discovery: hypoxia-inducible factor-1 (HIF-1)-active cells as a target for cancer therapy S Kizaka-Kondoh, T Kuchimaru, T Kadonosono Journal of pharmacological sciences 115 (4), 440-445, 2011 | 23 | 2011 |
| Imaging hypoxic stress and the treatment of amyotrophic lateral sclerosis with dimethyloxalylglycine in a mice model E Nomura, Y Ohta, K Tadokoro, J Shang, T Feng, X Liu, X Shi, ... Neuroscience 415, 31-43, 2019 | 22 | 2019 |
| Bone resorption facilitates osteoblastic bone metastatic colonization by cooperation of insulin‐like growth factor and hypoxia T Kuchimaru, T Hoshino, T Aikawa, H Yasuda, T Kobayashi, ... Cancer Science 105 (5), 553-559, 2014 | 22 | 2014 |
| Design strategy to create antibody mimetics harbouring immobilised complementarity determining region peptides for practical use T Kadonosono, W Yimchuen, Y Ota, K See, T Furuta, T Shiozawa, ... Scientific reports 10 (1), 891, 2020 | 20 | 2020 |
