TREM2 in neurodegenerative diseases TR Jay, VE von Saucken, GE Landreth Molecular neurodegeneration 12 (1), 1-33, 2017 | 351 | 2017 |
Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation U Dettmer, AJ Newman, F Soldner, ES Luth, NC Kim, VE Von Saucken, ... Nature communications 6 (1), 1-16, 2015 | 330 | 2015 |
The T rem 2 R47H variant confers loss-of-function-like phenotypes in Alzheimer’s disease PJ Cheng-Hathaway, EG Reed-Geaghan, TR Jay, BT Casali, SM Bemiller, ... Molecular neurodegeneration 13 (1), 1-12, 2018 | 194 | 2018 |
KTKEGV repeat motifs are key mediators of normal α-synuclein tetramerization: Their mutation causes excess monomers and neurotoxicity U Dettmer, AJ Newman, VE von Saucken, T Bartels, D Selkoe Proceedings of the National Academy of Sciences 112 (31), 9596-9601, 2015 | 177 | 2015 |
Loss of native α-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cells U Dettmer, N Ramalingam, VE von Saucken, TE Kim, AJ Newman, ... Human molecular genetics 26 (18), 3466-3481, 2017 | 83 | 2017 |
TREM2 is required for microglial instruction of astrocytic synaptic engulfment in neurodevelopment TR Jay, VE von Saucken, B Muñoz, JF Codocedo, BK Atwood, BT Lamb, ... Glia 67 (10), 1873-1892, 2019 | 71 | 2019 |
Corrigendum: Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation U Dettmer, AJ Newman, F Soldner, ES Luth, NC Kim, VE Von Saucken, ... Nature communications 6, 2015 | 20 | 2015 |
The effect of amyloid on microglia-neuron interactions before plaque onset occurs independently of TREM2 in a mouse model of Alzheimer's disease VE von Saucken, TR Jay, GE Landreth Neurobiology of disease 145, 105072, 2020 | 15 | 2020 |
Crowded organelles, lipid accumulation, and abnormal membrane tubulation in cellular models of enhanced α-synuclein membrane interaction M Ericsson, V von Saucken, AJ Newman, L Doehr, C Hoesch, TE Kim, ... Brain Research 1758, 147349, 2021 | 11 | 2021 |