Gregory D Fairn
Gregory D Fairn
Professor, Dept. of Pathology, Dalhousie University
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How nascent phagosomes mature to become phagolysosomes
GD Fairn, S Grinstein
Trends in immunology 33 (8), 397-405, 2012
High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine
GD Fairn, NL Schieber, N Ariotti, S Murphy, L Kuerschner, RI Webb, ...
Journal of Cell Biology 194 (2), 257-275, 2011
VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis
R Hua, D Cheng, Coyaud, S Freeman, E Di Pietro, Y Wang, A Vissa, ...
Journal of Cell Biology 216 (2), 367-377, 2017
Complementary probes reveal that phosphatidylserine is required for the proper transbilayer distribution of cholesterol
M Maekawa, GD Fairn
Journal of cell science 128 (7), 1422-1433, 2015
Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins
D Schlam, RD Bagshaw, SA Freeman, RF Collins, T Pawson, GD Fairn, ...
Nature communications 6 (1), 8623, 2015
Phosphatidylserine is polarized and required for proper Cdc42 localization and for development of cell polarity
GD Fairn, M Hermansson, P Somerharju, S Grinstein
Nature cell biology 13 (12), 1424-1430, 2011
Phospholipid subcellular localization and dynamics
Y Yang, M Lee, GD Fairn
Journal of Biological Chemistry 293 (17), 6230-6240, 2018
PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER–PM contact sites
M Sohn, M Korzeniowski, JP Zewe, RC Wills, GRV Hammond, ...
Journal of Cell Biology 217 (5), 1797-1813, 2018
Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation
T Yeung, B Heit, JF Dubuisson, GD Fairn, B Chiu, R Inman, A Kapus, ...
Journal of cell biology 185 (5), 917-928, 2009
Transcellular vesicular transport in epithelial and endothelial cells: Challenges and opportunities
KYY Fung, GD Fairn, WL Lee
Traffic 19 (1), 5-18, 2018
Cleavage furrow organization requires PIP2-mediated recruitment of anillin
J Liu, GD Fairn, DF Ceccarelli, F Sicheri, A Wilde
Current biology 22 (1), 64-69, 2012
SR-BI mediated transcytosis of HDL in brain microvascular endothelial cells is independent of caveolin, clathrin, and PDZK1
KY Fung, C Wang, S Nyegaard, B Heit, GD Fairn, WL Lee
Frontiers in physiology 8, 841, 2017
The oxysterol binding protein Kes1p regulates Golgi apparatus phosphatidylinositol-4-phosphate function
GD Fairn, AJ Curwin, CJ Stefan, CR McMaster
Proceedings of the National Academy of Sciences 104 (39), 15352-15357, 2007
Palmitoylation of NOD1 and NOD2 is required for bacterial sensing
Y Lu, Y Zheng, Coyaud, C Zhang, A Selvabaskaran, Y Yu, Z Xu, ...
Science 366 (6464), 460-467, 2019
Molecular probes to visualize the location, organization and dynamics of lipids
M Maekawa, GD Fairn
Journal of cell science 127 (22), 4801-4812, 2014
Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes
M Bohdanowicz, D Schlam, M Hermansson, D Rizzuti, GD Fairn, ...
Molecular biology of the cell 24 (11), 1700-1712, 2013
Inhibition of acid sphingomyelinase depletes cellular phosphatidylserine and mislocalizes K-Ras from the plasma membrane
K Cho, D van der Hoeven, Y Zhou, M Maekawa, X Ma, W Chen, GD Fairn, ...
Molecular and cellular biology 36 (2), 363-374, 2016
Akt-ing up just about everywhere: compartment-specific Akt activation and function in receptor tyrosine kinase signaling
MG Sugiyama, GD Fairn, CN Antonescu
Frontiers in Cell and Developmental Biology 7, 70, 2019
An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis
GD Fairn, K Ogata, RJ Botelho, PD Stahl, RA Anderson, P De Camilli, ...
Journal of cell biology 187 (5), 701-714, 2009
Distribution, dynamics and functional roles of phosphatidylserine within the cell
JG Kay, GD Fairn
Cell Communication and Signaling 17 (1), 126, 2019
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