Demand-adapted regulation of early hematopoiesis in infection and inflammation H Takizawa, S Boettcher, MG Manz Blood 119 (13), 2991-3002, 2012 | 304 | 2012 |
BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups ML Berres, KPH Lim, T Peters, J Price, H Takizawa, H Salmon, J Idoyaga, ... Journal of Experimental Medicine 211 (4), 669-683, 2014 | 285 | 2014 |
Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation H Takizawa, RR Regoes, CS Boddupalli, S Bonhoeffer, MG Manz Journal of Experimental Medicine 208 (2), 273-284, 2011 | 266 | 2011 |
Human hemato-lymphoid system mice: current use and future potential for medicine A Rongvaux, H Takizawa, T Strowig, T Willinger, EE Eynon, RA Flavell, ... Annual review of immunology 31, 635-674, 2013 | 259 | 2013 |
Engineering of a functional bone organ through endochondral ossification C Scotti, E Piccinini, H Takizawa, A Todorov, P Bourgine, ... Proceedings of the National Academy of Sciences 110 (10), 3997-4002, 2013 | 249 | 2013 |
Humanized mice for modeling human infectious disease: challenges, progress, and outlook N Legrand, A Ploss, R Balling, PD Becker, C Borsotti, N Brezillon, ... Cell host & microbe 6 (1), 5-9, 2009 | 233 | 2009 |
Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo A Rongvaux, T Willinger, H Takizawa, C Rathinam, W Auerbach, ... Proceedings of the National Academy of Sciences 108 (6), 2378-2383, 2011 | 219 | 2011 |
Transgenic expression of human signal regulatory protein alpha in Rag2−/− γc−/− mice improves engraftment of human hematopoietic cells in humanized mice T Strowig, A Rongvaux, C Rathinam, H Takizawa, C Borsotti, W Philbrick, ... Proceedings of the National Academy of Sciences 108 (32), 13218-13223, 2011 | 210 | 2011 |
Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung T Willinger, A Rongvaux, H Takizawa, GD Yancopoulos, DM Valenzuela, ... Proceedings of the National Academy of Sciences 108 (6), 2390-2395, 2011 | 210 | 2011 |
Inflamm-aging of hematopoiesis, hematopoietic stem cells, and the bone marrow microenvironment LV Kovtonyuk, K Fritsch, X Feng, MG Manz, H Takizawa Frontiers in immunology 7, 502, 2016 | 154 | 2016 |
The analysis, roles and regulation of quiescence in hematopoietic stem cells A Nakamura-Ishizu, H Takizawa, T Suda Development 141 (24), 4656-4666, 2014 | 137 | 2014 |
Cutting edge: LPS-induced emergency myelopoiesis depends on TLR4-expressing nonhematopoietic cells S Boettcher, P Ziegler, MA Schmid, H Takizawa, N van Rooijen, M Kopf, ... The Journal of Immunology 188 (12), 5824-5828, 2012 | 111 | 2012 |
Pathogen-induced TLR4-TRIF innate immune signaling in hematopoietic stem cells promotes proliferation but reduces competitive fitness H Takizawa, K Fritsch, LV Kovtonyuk, Y Saito, C Yakkala, K Jacobs, ... Cell Stem Cell 21 (2), 225-240. e5, 2017 | 102 | 2017 |
Lnk regulates integrin αIIbβ3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo H Takizawa, S Nishimura, N Takayama, A Oda, H Nishikii, Y Morita, ... The Journal of clinical investigation 120 (1), 179-190, 2010 | 82 | 2010 |
Bone marrow dendritic cell progenitors sense pathogens via Toll-like receptors and subsequently migrate to inflamed lymph nodes MA Schmid, H Takizawa, DR Baumjohann, Y Saito, MG Manz Blood, The Journal of the American Society of Hematology 118 (18), 4829-4840, 2011 | 74 | 2011 |
Myeloproliferative neoplasms can be initiated from a single hematopoietic stem cell expressing JAK2-V617F P Lundberg, H Takizawa, L Kubovcakova, G Guo, H Hao-Shen, ... Journal of Experimental Medicine 211 (11), 2213-2230, 2014 | 67 | 2014 |
Macrophage tolerance: CD47–SIRP-α–mediated signals matter H Takizawa, MG Manz Nature immunology 8 (12), 1287-1289, 2007 | 56 | 2007 |
Growth and maturation of megakaryocytes is regulated by Lnk/Sh2b3 adaptor protein through crosstalk between cytokine-and integrin-mediated signals H Takizawa, K Eto, A Yoshikawa, H Nakauchi, K Takatsu, S Takaki Experimental hematology 36 (7), 897-906, 2008 | 42 | 2008 |
Enhanced engraftment of hematopoietic stem/progenitor cells by the transient inhibition of an adaptor protein, Lnk H Takizawa, C Kubo-Akashi, I Nobuhisa, SM Kwon, M Iseki, T Taga, ... Blood 107 (7), 2968-2975, 2006 | 41 | 2006 |
Ex vivo expansion of hematopoietic stem cells: mission accomplished? H Takizawa, MG Manz Swiss medical weekly 141 (5152), 2011 | 39 | 2011 |