|Demand-adapted regulation of early hematopoiesis in infection and inflammation|
H Takizawa, S Boettcher, MG Manz
Blood 119 (13), 2991-3002, 2012
|BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups|
ML Berres, KPH Lim, T Peters, J Price, H Takizawa, H Salmon, J Idoyaga, ...
Journal of Experimental Medicine 211 (4), 669-683, 2014
|Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation|
H Takizawa, RR Regoes, CS Boddupalli, S Bonhoeffer, MG Manz
Journal of Experimental Medicine 208 (2), 273-284, 2011
|Human hemato-lymphoid system mice: current use and future potential for medicine|
A Rongvaux, H Takizawa, T Strowig, T Willinger, EE Eynon, RA Flavell, ...
Annual review of immunology 31, 635-674, 2013
|Engineering of a functional bone organ through endochondral ossification|
C Scotti, E Piccinini, H Takizawa, A Todorov, P Bourgine, ...
Proceedings of the National Academy of Sciences 110 (10), 3997-4002, 2013
|Humanized mice for modeling human infectious disease: challenges, progress, and outlook|
N Legrand, A Ploss, R Balling, PD Becker, C Borsotti, N Brezillon, ...
Cell host & microbe 6 (1), 5-9, 2009
|Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo|
A Rongvaux, T Willinger, H Takizawa, C Rathinam, W Auerbach, ...
Proceedings of the National Academy of Sciences 108 (6), 2378-2383, 2011
|Transgenic expression of human signal regulatory protein alpha in Rag2−/− γc−/− mice improves engraftment of human hematopoietic cells in humanized mice|
T Strowig, A Rongvaux, C Rathinam, H Takizawa, C Borsotti, W Philbrick, ...
Proceedings of the National Academy of Sciences 108 (32), 13218-13223, 2011
|Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung|
T Willinger, A Rongvaux, H Takizawa, GD Yancopoulos, DM Valenzuela, ...
Proceedings of the National Academy of Sciences 108 (6), 2390-2395, 2011
|Inflamm-aging of hematopoiesis, hematopoietic stem cells, and the bone marrow microenvironment|
LV Kovtonyuk, K Fritsch, X Feng, MG Manz, H Takizawa
Frontiers in immunology 7, 502, 2016
|The analysis, roles and regulation of quiescence in hematopoietic stem cells|
A Nakamura-Ishizu, H Takizawa, T Suda
Development 141 (24), 4656-4666, 2014
|Cutting edge: LPS-induced emergency myelopoiesis depends on TLR4-expressing nonhematopoietic cells|
S Boettcher, P Ziegler, MA Schmid, H Takizawa, N van Rooijen, M Kopf, ...
The Journal of Immunology 188 (12), 5824-5828, 2012
|Pathogen-induced TLR4-TRIF innate immune signaling in hematopoietic stem cells promotes proliferation but reduces competitive fitness|
H Takizawa, K Fritsch, LV Kovtonyuk, Y Saito, C Yakkala, K Jacobs, ...
Cell Stem Cell 21 (2), 225-240. e5, 2017
|Lnk regulates integrin αIIbβ3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo|
H Takizawa, S Nishimura, N Takayama, A Oda, H Nishikii, Y Morita, ...
The Journal of clinical investigation 120 (1), 179-190, 2010
|Bone marrow dendritic cell progenitors sense pathogens via Toll-like receptors and subsequently migrate to inflamed lymph nodes|
MA Schmid, H Takizawa, DR Baumjohann, Y Saito, MG Manz
Blood, The Journal of the American Society of Hematology 118 (18), 4829-4840, 2011
|Myeloproliferative neoplasms can be initiated from a single hematopoietic stem cell expressing JAK2-V617F|
P Lundberg, H Takizawa, L Kubovcakova, G Guo, H Hao-Shen, ...
Journal of Experimental Medicine 211 (11), 2213-2230, 2014
|Macrophage tolerance: CD47–SIRP-α–mediated signals matter|
H Takizawa, MG Manz
Nature immunology 8 (12), 1287-1289, 2007
|Growth and maturation of megakaryocytes is regulated by Lnk/Sh2b3 adaptor protein through crosstalk between cytokine-and integrin-mediated signals|
H Takizawa, K Eto, A Yoshikawa, H Nakauchi, K Takatsu, S Takaki
Experimental hematology 36 (7), 897-906, 2008
|Enhanced engraftment of hematopoietic stem/progenitor cells by the transient inhibition of an adaptor protein, Lnk|
H Takizawa, C Kubo-Akashi, I Nobuhisa, SM Kwon, M Iseki, T Taga, ...
Blood 107 (7), 2968-2975, 2006
|Ex vivo expansion of hematopoietic stem cells: mission accomplished?|
H Takizawa, MG Manz
Swiss medical weekly 141 (5152), 2011