Regulation of lysozyme activity based on thermotolerant protein/smart polymer complex formation S Ganguli, K Yoshimoto, S Tomita, H Sakuma, T Matsuoka, K Shiraki, ... Journal of the American Chemical Society 131 (18), 6549-6553, 2009 | 64 | 2009 |
Enzyme hyperactivation system based on a complementary charged pair of polyelectrolytes and substrates T Kurinomaru, S Tomita, Y Hagihara, K Shiraki Langmuir 30 (13), 3826-3831, 2014 | 56 | 2014 |
Amidated amino acids are prominent additives for preventing heat-induced aggregation of lysozyme T Matsuoka, S Tomita, H Hamada, K Shiraki Journal of Bioscience and Bioengineering 103 (5), 440-443, 2007 | 52 | 2007 |
Improved complementary polymer pair system: Switching for enzyme activity by PEGylated polymers T Kurinomaru, S Tomita, S Kudo, S Ganguli, Y Nagasaki, K Shiraki Langmuir 28 (9), 4334-4338, 2012 | 46 | 2012 |
Quadruplex folding promotes the condensation of linker histones and DNAs via liquid–liquid phase separation M Mimura, S Tomita, Y Shinkai, T Hosokai, H Kumeta, T Saio, K Shiraki, ... Journal of the American Chemical Society 143 (26), 9849-9857, 2021 | 44 | 2021 |
Arginine controls heat‐induced cluster–cluster aggregation of lysozyme at around the isoelectric point S Tomita, H Yoshikawa, K Shiraki Biopolymers 95 (10), 695-701, 2011 | 42 | 2011 |
Small amine molecules: solvent design toward facile improvement of protein stability against aggregation and inactivation K Shiraki, S Tomita, N Inoue Current Pharmaceutical Biotechnology 17 (2), 116-125, 2016 | 38 | 2016 |
Arginine inhibits adsorption of proteins on polystyrene surface Y Shikiya, S Tomita, T Arakawa, K Shiraki PLoS One 8 (8), e70762, 2013 | 35 | 2013 |
A polyion complex sensor array for markerless and noninvasive identification of differentiated mesenchymal stem cells from human adipose tissue S Tomita, M Sakao, R Kurita, O Niwa, K Yoshimoto Chemical Science 6 (10), 5831-5836, 2015 | 33 | 2015 |
Environment-sensitive turn-on fluorescent polyamino acid: Fingerprinting protein populations with post-translational modifications S Tomita, S Ishihara, R Kurita ACS Applied Materials & Interfaces 9 (27), 22970-22976, 2017 | 31 | 2017 |
Enzyme switch by complementary polymer pair system (CPPS) S Tomita, L Ito, H Yamaguchi, G Konishi, Y Nagasaki, K Shiraki Soft Matter 6 (21), 5320-5326, 2010 | 30 | 2010 |
A multi-fluorescent DNA/graphene oxide conjugate sensor for signature-based protein discrimination S Tomita, S Ishihara, R Kurita Sensors 17 (10), 2194, 2017 | 29 | 2017 |
Artificial modification of an enzyme for construction of cross-reactive polyion complexes to fingerprint signatures of proteins and mammalian cells S Tomita, O Niwa, R Kurita Analytical chemistry 88 (18), 9079-9086, 2016 | 27 | 2016 |
One-Component Array Based on a Dansyl-Modified Polylysine: Generation of Differential Fluorescent Signatures for the Discrimination of Human Cells H Sugai, S Tomita, S Ishihara, R Kurita ACS Sensors 4 (4), 827-831, 2019 | 26 | 2019 |
Biomimicry Recognition of Proteins and Cells Using a Small Array of Block Copolymers Appended with Amino Acids and Fluorophores S Tomita, S Ishihara, R Kurita ACS Applied Materials & Interfaces 11 (7), 6751-6758, 2019 | 25 | 2019 |
Poly (acrylic acid) is a common noncompetitive inhibitor for cationic enzymes with high affinity and reversibility S Tomita, K Shiraki Journal of Polymer Science Part A: Polymer Chemistry 49 (17), 3835-3841, 2011 | 25 | 2011 |
Why do solution additives suppress the heat‐induced inactivation of proteins? Inhibition of chemical modifications S Tomita, K Shiraki Biotechnology Progress 27 (3), 855-862, 2011 | 25 | 2011 |
Polyion complex libraries possessing naturally occurring differentiation for pattern-based protein discrimination S Tomita, K Yoshimoto Chemical Communications 49 (88), 10430-10432, 2013 | 24 | 2013 |
Dynamic behavior of liquid droplets with enzyme compartmentalization triggered by sequential glycolytic enzyme reactions T Ura, S Tomita, K Shiraki Chemical Communications 57 (93), 12544-12547, 2021 | 23 | 2021 |
Noncovalent PEGylation through protein–polyelectrolyte interaction: Kinetic experiment and molecular dynamics simulation T Kurinomaru, K Kuwada, S Tomita, T Kameda, K Shiraki The Journal of Physical Chemistry B 121 (28), 6785-6791, 2017 | 22 | 2017 |