Shunsuke Tomita
Shunsuke Tomita
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Regulation of lysozyme activity based on thermotolerant protein/smart polymer complex formation
S Ganguli, K Yoshimoto, S Tomita, H Sakuma, T Matsuoka, K Shiraki, ...
Journal of the American Chemical Society 131 (18), 6549-6553, 2009
Amidated amino acids are prominent additives for preventing heat-induced aggregation of lysozyme
T Matsuoka, S Tomita, H Hamada, K Shiraki
Journal of Bioscience and Bioengineering 103 (5), 440-443, 2007
Improved complementary polymer pair system: Switching for enzyme activity by PEGylated polymers
T Kurinomaru, S Tomita, S Kudo, S Ganguli, Y Nagasaki, K Shiraki
Langmuir 28 (9), 4334-4338, 2012
Enzyme hyperactivation system based on a complementary charged pair of polyelectrolytes and substrates
T Kurinomaru, S Tomita, Y Hagihara, K Shiraki
Langmuir 30 (13), 3826-3831, 2014
Arginine controls heat‐induced cluster–cluster aggregation of lysozyme at around the isoelectric point
S Tomita, H Yoshikawa, K Shiraki
Biopolymers 95 (10), 695-701, 2011
Small amine molecules: solvent design toward facile improvement of protein stability against aggregation and inactivation
K Shiraki, S Tomita, N Inoue
Current Pharmaceutical Biotechnology 17 (2), 116-125, 2016
Enzyme switch by complementary polymer pair system (CPPS)
S Tomita, L Ito, H Yamaguchi, G Konishi, Y Nagasaki, K Shiraki
Soft Matter 6 (21), 5320-5326, 2010
Arginine inhibits adsorption of proteins on polystyrene surface
Y Shikiya, S Tomita, T Arakawa, K Shiraki
PLoS One 8 (8), e70762, 2013
A polyion complex sensor array for markerless and noninvasive identification of differentiated mesenchymal stem cells from human adipose tissue
S Tomita, M Sakao, R Kurita, O Niwa, K Yoshimoto
Chemical Science 6 (10), 5831-5836, 2015
Poly (acrylic acid) is a common noncompetitive inhibitor for cationic enzymes with high affinity and reversibility
S Tomita, K Shiraki
Journal of Polymer Science Part A: Polymer Chemistry 49 (17), 3835-3841, 2011
Polyion complex libraries possessing naturally occurring differentiation for pattern-based protein discrimination
S Tomita, K Yoshimoto
Chemical Communications 49 (88), 10430-10432, 2013
Artificial modification of an enzyme for construction of cross-reactive polyion complexes to fingerprint signatures of proteins and mammalian cells
S Tomita, O Niwa, R Kurita
Analytical chemistry 88 (18), 9079-9086, 2016
Enzymatic fingerprinting of structurally similar homologous proteins using polyion complex library constructed by tuning PEGylated polyamine functionalities
S Tomita, T Soejima, K Shiraki, K Yoshimoto
Analyst 139 (23), 6100-6103, 2014
Environment-sensitive turn-on fluorescent polyamino acid: Fingerprinting protein populations with post-translational modifications
S Tomita, S Ishihara, R Kurita
ACS Applied Materials & Interfaces 9 (27), 22970-22976, 2017
Why do solution additives suppress the heat‐induced inactivation of proteins? Inhibition of chemical modifications
S Tomita, K Shiraki
Biotechnology Progress 27 (3), 855-862, 2011
Different mechanisms of action of poly (ethylene glycol) and arginine on thermal inactivation of lysozyme and ribonuclease A
S Tomita, Y Nagasaki, K Shiraki
Biotechnology and Bioengineering 109 (10), 2543-2552, 2012
Biomimicry Recognition of Proteins and Cells Using a Small Array of Block Copolymers Appended with Amino Acids and Fluorophores
S Tomita, S Ishihara, R Kurita
ACS Applied Materials & Interfaces 11 (7), 6751-6758, 2019
A multi-fluorescent DNA/graphene oxide conjugate sensor for signature-based protein discrimination
S Tomita, S Ishihara, R Kurita
Sensors 17 (10), 2194, 2017
Noncovalent PEGylation through Protein–Polyelectrolyte Interaction: Kinetic Experiment and Molecular Dynamics Simulation
T Kurinomaru, K Kuwada, S Tomita, T Kameda, K Shiraki
The Journal of Physical Chemistry B 121 (28), 6785-6791, 2017
One-step identification of antibody degradation pathways using fluorescence signatures generated by cross-reactive DNA-based arrays
S Tomita, A Matsuda, S Nishinami, R Kurita, K Shiraki
Analytical Chemistry 89 (15), 7818-7822, 2017
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