Nonpeptide orexin type-2 receptor agonist ameliorates narcolepsy-cataplexy symptoms in mouse models Y Irukayama-Tomobe, Y Ogawa, H Tominaga, Y Ishikawa, N Hosokawa, ... Proceedings of the National Academy of Sciences 114 (22), 5731-5736, 2017 | 132 | 2017 |
Design and synthesis of non-peptide, selective orexin receptor 2 agonists T Nagahara, T Saitoh, N Kutsumura, Y Irukayama-Tomobe, Y Ogawa, ... Journal of medicinal chemistry 58 (20), 7931-7937, 2015 | 124 | 2015 |
Anodic Oxidation on a Boron‐Doped Diamond Electrode Mediated by Methoxy Radicals T Sumi, T Saitoh, K Natsui, T Yamamoto, M Atobe, Y Einaga, S Nishiyama Angewandte Chemie International Edition 22 (51), 5443-5446, 2012 | 99 | 2012 |
Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors Y Wang, L Cao, CY Lee, T Matsuo, K Wu, G Asher, L Tang, T Saitoh, ... Nature communications 9 (1), 1-15, 2018 | 60 | 2018 |
Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution R Nishihara, H Suzuki, E Hoshino, S Suganuma, M Sato, T Saitoh, ... Chemical communications 51 (2), 391-394, 2014 | 58 | 2014 |
A solvent-directed stereoselective and electrocatalytic synthesis of diisoeugenol T Yamamoto, B Riehl, K Naba, K Nakahara, A Wiebe, T Saitoh, ... Chemical communications 54 (22), 2771-2773, 2018 | 43 | 2018 |
Application of electrochemically generated hypervalent iodine oxidant to natural products synthesis D Kajiyama, T Saitoh, S Nishiyama Electrochemistry 81 (5), 319-324, 2013 | 43 | 2013 |
Design and synthesis of potent and highly selective orexin 1 receptor antagonists with a morphinan skeleton and their pharmacologies H Nagase, N Yamamoto, M Yata, S Ohrui, T Okada, T Saitoh, ... Journal of Medicinal Chemistry 60 (3), 1018-1040, 2017 | 42 | 2017 |
Oxidative cyclization reactions of tryptamine utilizing hypervalent iodobenzene in routes for pyrroloindole alkaloid synthesis D Kajiyama, T Saitoh, S Yamaguchi, S Nishiyama Synthesis 44 (11), 1667-1671, 2012 | 35 | 2012 |
Enhancing endogenous adenosine A2A receptor signaling induces slow-wave sleep without affecting body temperature and cardiovascular function M Korkutata, T Saitoh, Y Cherasse, S Ioka, F Duo, R Qin, N Murakoshi, ... Neuropharmacology 144, 122-132, 2019 | 33 | 2019 |
Synthesis of firefly luciferin analogues and evaluation of the luminescent properties S Ioka, T Saitoh, S Iwano, K Suzuki, SA Maki, A Miyawaki, M Imoto, ... Chemistry–A European Journal 22 (27), 9330-9337, 2016 | 31 | 2016 |
Total syntheses of amphidinolides B, G, and H. A Hara, R Morimoto, Y Iwasaki, T Saitoh, Y Ishikawa, S Nishiyama Angewandte Chemie (International ed. in English) 51 (39), 9877-9880, 2012 | 28 | 2012 |
Nonpeptide orexin-2 receptor agonist attenuates morphine-induced sedative effects in rats S Toyama, N Shimoyama, Y Tagaito, H Nagase, T Saitoh, M Yanagisawa, ... Anesthesiology 128 (5), 992-1003, 2018 | 27 | 2018 |
Sequential paired electrosynthesis of a diaryl ether derivative using an electrochemical microreactor T Kashiwagi, T Fuchigami, T Saito, S Nishiyama, M Atobe Chemistry Letters 43 (6), 799-801, 2014 | 27 | 2014 |
Cerebral capillary blood flow upsurge during REM sleep is mediated by A2a receptors CJ Tsai, T Nagata, CY Liu, T Suganuma, T Kanda, T Miyazaki, K Liu, ... Cell reports 36 (7), 2021 | 26 | 2021 |
An allylated firefly luciferin analogue with luciferase specific response in living cells Y Ikeda, T Saitoh, K Niwa, T Nakajima, N Kitada, SA Maki, M Sato, ... Chemical communications 54 (14), 1774-1777, 2018 | 25 | 2018 |
Toward bioluminescence in the near-infrared region: Tuning the emission wavelength of firefly luciferin analogues by allyl substitution N Kitada, T Saitoh, Y Ikeda, S Iwano, R Obata, H Niwa, T Hirano, ... Tetrahedron letters 59 (12), 1087-1090, 2018 | 24 | 2018 |
Cathodic reductive coupling of methyl cinnamate on boron-doped diamond electrodes and synthesis of new neolignan-type products T Kojima, R Obata, T Saito, Y Einaga, S Nishiyama Beilstein Journal of Organic Chemistry 11 (1), 200-203, 2015 | 23 | 2015 |
Efficient synthesis of (±)-parasitenone, a novel inhibitor of NF-κB T Saitoh, E Suzuki, A Takasugi, R Obata, Y Ishikawa, K Umezawa, ... Bioorganic & medicinal chemistry letters 19 (18), 5383-5386, 2009 | 23 | 2009 |
Controlled decoration of boron-doped diamond electrodes by electrochemical click reaction (e− CLICK) T Yamamoto, M Akahori, K Natsui, T Saitoh, Y Einaga Carbon 130, 350-354, 2018 | 22 | 2018 |