Kerry Geiler-Samerotte
Kerry Geiler-Samerotte
Assistant Professor, Center for Mechanisms of Evolution & School of Life Sciences, Arizona State
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The ecoresponsive genome of Daphnia pulex
JK Colbourne, ME Pfrender, D Gilbert, WK Thomas, A Tucker, TH Oakley, ...
Science 331 (6017), 555-561, 2011
Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast
KA Geiler-Samerotte, MF Dion, BA Budnik, SM Wang, DL Hartl, ...
Proceedings of the National Academy of Sciences 108 (2), 680-685, 2011
Development of a comprehensive genotype-to-fitness map of adaptation-driving mutations in yeast
S Venkataram, B Dunn, Y Li, A Agarwala, J Chang, ER Ebel, ...
Cell 166 (6), 1585-1596. e22, 2016
The details in the distributions: why and how to study phenotypic variability
KA Geiler-Samerotte, CR Bauer, S Li, N Ziv, D Gresham, ML Siegal
Current opinion in biotechnology 24 (4), 752-759, 2013
Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects
F Pangilinan, AM Molloy, JL Mills, JF Troendle, A Parle-McDermott, ...
BMC medical genetics 13 (1), 62, 2012
Selection transforms the landscape of genetic variation interacting with Hsp90
KA Geiler-Samerotte, YO Zhu, BE Goulet, DW Hall, ML Siegal
PLoS biology 14 (10), e2000465, 2016
Construction of a high resolution linkage disequilibrium map to evaluate common genetic variation in TP53 and neural tube defect risk in an Irish population
F Pangilinan, K Geiler, J Dolle, J Troendle, DA Swanson, AM Molloy, ...
American Journal of Medical Genetics Part A 146 (20), 2617-2625, 2008
Decanalizing thinking on genetic canalization
K Geiler-Samerotte, FMO Sartori, ML Siegal
Seminars in cell & developmental biology 88, 54-66, 2019
A Δ11 desaturase gene genealogy reveals two divergent allelic classes within the European corn borer (Ostrinia nubilalis)
KA Geiler, RG Harrison
BMC evolutionary biology 10 (1), 112, 2010
Quantifying condition-dependent intracellular protein levels enables high-precision fitness estimates
KA Geiler-Samerotte, T Hashimoto, MF Dion, BA Budnik, EM Airoldi, ...
PloS one 8 (9), e75320, 2013
Why and how to study genetic changes with context-dependent effects
Y Eguchi, G Bilolikar, K Geiler-Samerotte
Current opinion in genetics & development 58, 95-102, 2019
Extent and context dependence of pleiotropy revealed by high-throughput single-cell phenotyping
KA Geiler-Samerotte, S Li, C Lazaris, A Taylor, N Ziv, C Ramjeawan, ...
PLoS biology 18 (8), e3000836, 2020
Emerging Frontiers in the Study of Molecular Evolution
DA Liberles, B Chang, K Geiler-Samerotte, A Goldman, J Hey, B Kaçar, ...
Journal of Molecular Evolution 88 (3), 211-226, 2020
A genotype-phenotype-fitness map reveals local modularity and global pleiotropy of adaptation
G Kinsler, K Geiler-Samerotte, DA Petrov
BioRxiv, 2020
Fitness variation across subtle environmental perturbations reveals local modularity and global pleiotropy of adaptation
G Kinsler, K Geiler-Samerotte, DA Petrov
Elife 9, e61271, 2020
The complete genome sequence of the Staphylococcus bacteriophage Metroid
A Crane, J Abaidoo, G Beltran, D Fry, C Furey, N Green, R Johal, ...
bioRxiv, 2020
Principles of Systems Biology, No. 11
G Wayne, A Graves, D Hassabis, S Saha, CA Weber, AA Hyman, ...
Cell Systems 3 (ARTICLE), 406-410, 2016
The selective cost of misfolded proteins and a concomitant evolutionary adaptation
K Geiler-Samerotte
Harvard University, 2011
論文 1–18