| Rapid and Mild Synthesis of Amino Acid N‐Carboxy Anhydrides: Basic‐to‐Acidic Flash Switching in a Microflow Reactor Y Otake, H Nakamura, S Fuse Angewandte Chemie International Edition 57 (35), 11389-11393, 2018 | 69 | 2018 |
| Peptide synthesis utilizing micro‐flow technology S Fuse, Y Otake, H Nakamura Chemistry–An Asian Journal 13 (24), 3818-3832, 2018 | 46 | 2018 |
| N‐Methylated Peptide Synthesis via Generation of an Acyl N‐Methylimidazolium Cation Accelerated by a Brønsted Acid Y Otake, Y Shibata, Y Hayashi, S Kawauchi, H Nakamura, S Fuse Angewandte Chemie 132 (31), 13025-13030, 2020 | 35 | 2020 |
| Peptide‐Chain Elongation Using Unprotected Amino Acids in a Micro‐Flow Reactor S Fuse, K Masuda, Y Otake, H Nakamura Chemistry–A European Journal 25 (66), 15091-15097, 2019 | 34 | 2019 |
| Rapid and Mild One‐Flow Synthetic Approach to Unsymmetrical Sulfamides Guided by Bayesian Optimization N Sugisawa, H Sugisawa, Y Otake, RV Krems, H Nakamura, S Fuse Chemistry‐Methods 1 (11), 484-490, 2021 | 30 | 2021 |
| Integrated Micro‐Flow Synthesis Based on Photochemical Wolff Rearrangement S Fuse, Y Otake, H Nakamura European Journal of Organic Chemistry 2017 (44), 6466-6473, 2017 | 21 | 2017 |
| Single‐Step, Rapid, and Mild Synthesis of β‐Amino Acid N‐Carboxy Anhydrides Using Micro‐Flow Technology N Sugisawa, Y Otake, H Nakamura, S Fuse Chemistry–An Asian Journal 15 (1), 79-84, 2020 | 20 | 2020 |
| Recent advances in the integrated micro-flow synthesis containing photochemical reactions Y Otake, H Nakamura, S Fuse Tetrahedron letters 59 (18), 1691-1697, 2018 | 17 | 2018 |
| Towards a Scalable Synthesis of 2‐Oxabicyclo [2.2. 0] hex‐5‐en‐3‐one Using Flow Photochemistry JD Williams, Y Otake, G Coussanes, I Saridakis, N Maulide, CO Kappe ChemPhotoChem 3 (5), 229-232, 2019 | 16 | 2019 |
| A Facile Preparation of α-Aryl Carboxylic Acid via One-Flow Arndt–Eistert Synthesis S Fuse, Y Otake, Y Mifune, H Tanaka Australian Journal of Chemistry 68 (11), 1657-1661, 2015 | 16 | 2015 |
| Photochemical benzylic bromination in continuous flow using BrCCl 3 and its application to telescoped p-methoxybenzyl protection O Frutos, C OliveráKappe Organic & Biomolecular Chemistry 17 (6), 1384-1388, 2019 | 14 | 2019 |
| Rapid and mild lactamization using highly electrophilic triphosgene in a microflow reactor S Fuse, K Komuro, Y Otake, H Masui, H Nakamura Chemistry–A European Journal 27 (27), 7525-7532, 2021 | 11 | 2021 |
| Sequential Nucleophilic Substitution of Phosphorus Trichloride with Alcohols in a Continuous‐Flow Reactor and Consideration of a Mechanism for Reduced Over‐reaction through the … H Kitamura, Y Otake, N Sugisawa, H Sugisawa, T Ida, H Nakamura, ... Chemistry–A European Journal 28 (37), e202200932, 2022 | 9 | 2022 |
| Flow synthesis of triptycene via triple cycloaddition of ynolate to benzyne T Iwata, T Yoshinaga, M Shindo Synlett 31 (19), 1903-1906, 2020 | 9 | 2020 |
| Size-controllable and scalable production of liposomes using a v-shaped mixer micro-flow reactor J Kawamura, H Kitamura, Y Otake, S Fuse, H Nakamura Organic Process Research & Development 24 (10), 2122-2127, 2020 | 8 | 2020 |
| Simultaneous Characterization of Reaction Kinetics and Enthalpy by Calorimetry Based on Spatially Resolved Temperature Profile in Flow Reactors Y Imamura, J Ogawa, Y Otake, H Itoh Organic Process Research & Development 27 (3), 470-476, 2023 | 2 | 2023 |
| A liquid-phase continuous-flow peptide synthesizer for preparing C-terminal free peptides Y Otake, K Adachi, Y Yamashita, N Iwanaga, H Sunakawa, T Shamoto, ... Reaction Chemistry & Engineering 8 (4), 863-870, 2023 | 2 | 2023 |
| Cover Feature: Peptide‐Chain Elongation Using Unprotected Amino Acids in a Micro‐Flow Reactor (Chem. Eur. J. 66/2019) S Fuse, K Masuda, Y Otake, H Nakamura Chemistry–A European Journal 25 (66), 15008-15008, 2019 | 1 | 2019 |
| Reaction analysis device, reaction analysis system, and reaction analysis method Y Imamura, Y Otake US Patent 11,420,173, 2022 | | 2022 |
| Cover Feature: Sequential Nucleophilic Substitution of Phosphorus Trichloride with Alcohols in a Continuous‐Flow Reactor and Consideration of a Mechanism for Reduced Over … H Kitamura, Y Otake, N Sugisawa, H Sugisawa, T Ida, H Nakamura, ... Chemistry–A European Journal 28 (37), e202201646, 2022 | | 2022 |
