Essential, nonredundant role for the phosphoinositide 3-kinase p110δ in signaling by the B-cell receptor complex ST Jou, N Carpino, Y Takahashi, R Piekorz, JR Chao, N Carpino, D Wang, ... Molecular and cellular biology, 2002 | 467 | 2002 |
Impact of the 3D microenvironment on phenotype, gene expression, and EGFR inhibition of colorectal cancer cell lines AC Luca, S Mersch, R Deenen, S Schmidt, I Messner, KL Schäfer, ... PloS one 8 (3), e59689, 2013 | 410 | 2013 |
Stat5 tetramer formation is associated with leukemogenesis R Moriggl, V Sexl, L Kenner, C Duntsch, K Stangl, S Gingras, A Hoffmeyer, ... Cancer cell 7 (1), 87-99, 2005 | 282 | 2005 |
Stat5a/b contribute to interleukin 7–induced B-cell precursor expansion, but abl- andbcr/abl-induced transformation are independent of Stat5 V Sexl, R Piekorz, R Moriggl, J Rohrer, MP Brown, KD Bunting, ... Blood, The Journal of the American Society of Hematology 96 (6), 2277-2283, 2000 | 259 | 2000 |
Stat5 activation is uniquely associated with cytokine signaling in peripheral T cells R Moriggl, V Sexl, R Piekorz, D Topham, JN Ihle Immunity 11 (2), 225-230, 1999 | 241 | 1999 |
Rho-kinase: regulation,(dys) function, and inhibition E Amin, BN Dubey, SC Zhang, L Gremer, R Dvorsky, JM Moll, MS Taha, ... Biological chemistry 394 (11), 1399-1410, 2013 | 200 | 2013 |
Stat5 expression is critical for mast cell development and survival CP Shelburne, ME McCoy, R Piekorz, V Sexl, KH Roh, SM Jacobs-Helber, ... Blood 102 (4), 1290-1297, 2003 | 174 | 2003 |
Tumor immune escape by the loss of homeostatic chemokine expression A Pivarcsi, A Müller, A Hippe, J Rieker, A Van Lierop, M Steinhoff, ... Proceedings of the National Academy of Sciences 104 (48), 19055-19060, 2007 | 161 | 2007 |
Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20α-hydroxysteroid dehydrogenase RP Piekorz, S Gingras, A Hoffmeyer, JN Ihle, Y Weinstein Molecular endocrinology 19 (2), 431-440, 2005 | 158 | 2005 |
Macrophages induce the inflammatory response in the pulmonary Arthus reaction through Gαi2 activation that controls C5aR and Fc receptor cooperation J Skokowa, SR Ali, O Felda, V Kumar, S Konrad, N Shushakova, ... The Journal of Immunology 174 (5), 3041-3050, 2005 | 148 | 2005 |
The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53‐regulated apoptosis RP Piekorz, A Hoffmeyer, CD Duntsch, C McKay, H Nakajima, V Sexl, ... The EMBO journal, 2002 | 132 | 2002 |
MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4 A Lang, S Grether-Beck, M Singh, F Kuck, S Jakob, A Kefalas, ... Aging (Albany NY) 8 (3), 484, 2016 | 124 | 2016 |
An obligatory requirement for the heterotrimeric G protein Gi3 in the antiautophagic action of insulin in the liver A Gohla, K Klement, RP Piekorz, K Pexa, S vom Dahl, K Spicher, V Dreval, ... Proceedings of the National Academy of Sciences 104 (8), 3003-3008, 2007 | 123 | 2007 |
SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy A Lang, R Anand, S Altinoluk-Hambüchen, H Ezzahoini, A Stefanski, ... Aging (Albany NY) 9 (10), 2163, 2017 | 120 | 2017 |
The transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival L Schneider, F Essmann, A Kletke, P Rio, H Hanenberg, W Wetzel, ... Journal of biological chemistry 282 (40), 29273-29283, 2007 | 105 | 2007 |
IL‐6 trans‐signaling controls liver regeneration after partial hepatectomy N Fazel Modares, R Polz, F Haghighi, L Lamertz, K Behnke, Y Zhuang, ... Hepatology 70 (6), 2075-2091, 2019 | 100 | 2019 |
The catalytic PI3K isoforms p110γ and p110δ contribute to B cell development and maintenance, transformation, and proliferation S Beer-Hammer, E Zebedin, M von Holleben, J Alferink, B Reis, P Dresing, ... Journal of leukocyte biology 87 (6), 1083-1095, 2010 | 72 | 2010 |
Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin MS Taha, K Nouri, LG Milroy, JM Moll, C Herrmann, L Brunsveld, ... PloS one 9 (3), e91465, 2014 | 69 | 2014 |
Phosphoinositide 3-kinases γ and δ, linkers of coordinate C5a receptor-Fcγ receptor activation and immune complex-induced inflammation S Konrad, SR Ali, K Wiege, SN Syed, L Engling, RP Piekorz, E Hirsch, ... Journal of biological chemistry 283 (48), 33296-33303, 2008 | 67 | 2008 |
Cellular senescence or EGFR signaling induces Interleukin 6 (IL-6) receptor expression controlled by mammalian target of rapamycin (mTOR) C Garbers, F Kuck, S Aparicio-Siegmund, K Konzak, M Kessenbrock, ... Cell Cycle 12 (21), 3421-3432, 2013 | 66 | 2013 |