Mutant PKCγ in spinocerebellar ataxia type 14 disrupts synapse elimination and long-term depression in Purkinje cells in vivo AN Shuvaev, H Horiuchi, T Seki, H Goenawan, T Irie, A Iizuka, N Sakai, ... Journal of Neuroscience 31 (40), 14324-14334, 2011 | 94 | 2011 |
Kv3. 3 channels harbouring a mutation of spinocerebellar ataxia type 13 alter excitability and induce cell death in cultured cerebellar Purkinje cells T Irie, Y Matsuzaki, Y Sekino, H Hirai The Journal of physiology 592 (1), 229-247, 2014 | 60 | 2014 |
Double-nanodomain coupling of calcium channels, ryanodine receptors, and BK channels controls the generation of burst firing T Irie, LO Trussell Neuron 96 (4), 856-870. e4, 2017 | 52 | 2017 |
MAM-2201, a synthetic cannabinoid drug of abuse, suppresses the synaptic input to cerebellar Purkinje cells via activation of presynaptic CB1 receptors T Irie, R Kikura-Hanajiri, M Usami, N Uchiyama, Y Goda, Y Sekino Neuropharmacology 95, 479-491, 2015 | 44 | 2015 |
Activation of GIRK channels by muscarinic receptors and group II metabotropic glutamate receptors suppresses Golgi cell activity in the cochlear nucleus of mice T Irie, I Fukui, H Ohmori Journal of neurophysiology 96 (5), 2633-2644, 2006 | 37 | 2006 |
Sub-toxic concentrations of nano-ZnO and nano-TiO2 suppress neurite outgrowth in differentiated PC12 cells T Irie, T Kawakami, K Sato, M Usami The Journal of toxicological sciences 42 (6), 723-729, 2017 | 22 | 2017 |
Presynaptic GABAB receptors modulate synaptic facilitation and depression at distinct synapses in fusiform cells of mouse dorsal cochlear nucleus T Irie, H Ohmori Biochemical and biophysical research communications 367 (2), 503-508, 2008 | 19 | 2008 |
Thyrotoxic rubber antioxidants, 2-mercaptobenzimidazole and its methyl derivatives, cause both inhibition and induction of drug-metabolizing activity in rat liver microsomes … A Miyajima, K Sakemi-Hoshikawa, M Usami, K Mitsunaga, T Irie, Y Ohno, ... Biochemical and biophysical research communications 492 (1), 116-120, 2017 | 13 | 2017 |
Effects of 13 developmentally toxic chemicals on the migration of rat cephalic neural crest cells in vitro M Usami, K Mitsunaga, A Miyajima, M Takamatu, S Kazama, T Irie, O Doi, ... Congenital Anomalies 56 (2), 52-59, 2016 | 8 | 2016 |
Inhibitory and inductive effects of 4-or 5-methyl-2-mercaptobenzimidazole, thyrotoxic and hepatotoxic rubber antioxidants, on several forms of cytochrome P450 in primary … A Miyajima, Y Kuroda, K Sakemi-Hoshikawa, M Usami, K Mitsunaga, ... Toxicology reports 7, 979-985, 2020 | 7 | 2020 |
Simple in vitro migration assay for neural crest cells and the opposite effects of all‐trans‐retinoic acid on cephalic‐ and trunk‐derived cells M Usami, K Mitsunaga, T Irie, A Miyajima, O Doi Congenital Anomalies 54 (3), 184-188, 2014 | 6 | 2014 |
A potential of methoxpropamine to be a widespread recreational drug: it blocks NMDA receptors and inhibits NMDA receptor-mediated synaptic transmission in a brain preparation … T Irie, D Yamazaki, R Kikura-Hanajiri Forensic Toxicology 39, 474-480, 2021 | 5 | 2021 |
Proteomic analysis of ethanol-induced embryotoxicity in cultured post-implantation rat embryos M Usami, K Mitsunaga, T Irie, A Miyajima, O Doi The Journal of Toxicological Sciences 39 (2), 285-292, 2014 | 5 | 2014 |
F-phenibut (β-(4-Fluorophenyl)-GABA), a potent GABAB receptor agonist, activates an outward-rectifying K+ current and suppresses the generation of action potentials in mouse … T Irie, D Yamazaki, R Kikura-Hanajiri European Journal of Pharmacology 884, 173437, 2020 | 4 | 2020 |
In vitro metabolism of 4-methyl-and 5-methyl-2-mercaptobenzimidazole, thyrotoxic and hepatotoxic rubber antioxidants, in rat liver microsomes A Miyajima, Y Kuroda, K Sakemi-Hoshikawa, M Usami, K Mitsunaga, ... Fundamental Toxicological Sciences 5 (3), 113-116, 2018 | 4 | 2018 |
Essential role of somatic Kv2 channels in high-frequency firing in cartwheel cells of the dorsal cochlear nucleus T Irie eneuro 8 (3), 2021 | 3 | 2021 |
Loose coupling between SK and P/Q-type Ca2+ channels in cartwheel cells of the dorsal cochlear nucleus T Irie Journal of Neurophysiology 122 (4), 1721-1727, 2019 | 3 | 2019 |
Various definitions of reproductive indices: A proposal for combined use of brief definitions M Usami, K Mitsunaga, T Irie, M Nakajima Congenital Anomalies 54 (1), 67-68, 2014 | 1 | 2014 |
Proteomic analysis of valproic acid-induced embryotoxicity in cultured post-implantation rat embryos M Usami, M Takamatsu, S Kazama, K Mitsunaga, A Miyajima, T Irie, O Doi, ... Fundamental Toxicological Sciences 4 (1), 31-35, 2017 | | 2017 |
A PKCγ mutation in spinocerebellar ataxia type 14 impairs PKC functions in a dominant-negative manner in cerebellar Purkinje cells in vivo A Shuvaev, H Horiuchi, A Iizuka, T Irie, M Iino, T Seki, N Sakai, H Hirai Neuroscience Research, S247, 2009 | | 2009 |