mTORC1 signaling controls multiple steps in ribosome biogenesis V Iadevaia, R Liu, CG Proud Seminars in cell & developmental biology 36, 113-120, 2014 | 258 | 2014 |
Re-evaluating the roles of proposed modulators of mammalian target of rapamycin complex 1 (mTORC1) signaling X Wang, BD Fonseca, H Tang, R Liu, A Elia, MJ Clemens, UA Bommer, ... Journal of Biological Chemistry 283 (45), 30482-30492, 2008 | 238 | 2008 |
Eukaryotic elongation factor 2 kinase as a drug target in cancer, and in cardiovascular and neurodegenerative diseases R Liu, CG Proud Acta Pharmacologica Sinica 37 (3), 285-294, 2016 | 103 | 2016 |
Eukaryotic elongation factor 2 kinase activity is controlled by multiple inputs from oncogenic signaling PCG Wang X, Regufe da Mota S, Liu R, Moore CE, Xie J, Lanucara F, Agarwala U ... Mol Cell Biol., 2014 | 97 | 2014 |
The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity JR Becker, R Cuella-Martin, M Barazas, R Liu, C Oliveira, AW Oliver, ... Nature communications 9 (1), 5406, 2018 | 91 | 2018 |
Severity of vanishing white matter disease does not correlate with deficits in eIF2B activity or the integrity of eIF2B complexes R Liu, HDW Van Der Lei, X Wang, NC Wortham, H Tang, CGM van Berkel, ... Human mutation 32 (9), 1036-1045, 2011 | 81 | 2011 |
Regulation of the elongation phase of protein synthesis enhances translation accuracy and modulates lifespan J Xie, V de Souza Alves, T von der Haar, L O’Keefe, RV Lenchine, ... Current Biology 29 (5), 737-749. e5, 2019 | 67 | 2019 |
Impairing the production of ribosomal RNA activates mammalian target of rapamycin complex 1 signalling and downstream translation factors R Liu, V Iadevaia, J Averous, PM Taylor, Z Zhang, CG Proud Nucleic Acids Research 42 (8), 5083-5096, 2014 | 51 | 2014 |
Adult-onset leukoencephalopathies with vanishing white matter with novel missense mutations in EIF2B2, EIF2B3, and EIF2B5 T Matsukawa, X Wang, R Liu, NC Wortham, Y Onuki, A Kubota, A Hida, ... Neurogenetics 12, 259-261, 2011 | 43 | 2011 |
Identification of residues that underpin interactions within the eukaryotic initiation factor (eIF2) 2B complex X Wang, NC Wortham, R Liu, CG Proud Journal of Biological Chemistry 287 (11), 8263-8274, 2012 | 29 | 2012 |
p90RSKs mediate the activation of ribosomal RNA synthesis by the hypertrophic agonist phenylephrine in adult cardiomyocytes Z Zhang, R Liu, PA Townsend, CG Proud Journal of molecular and cellular cardiology 59, 139-147, 2013 | 25 | 2013 |
Dynein light chain regulates adaptive and innate B cell development by distinctive genetic mechanisms A King, L Li, DM Wong, R Liu, R Bamford, A Strasser, DM Tarlinton, ... PLoS genetics 13 (9), e1007010, 2017 | 24 | 2017 |
ATP-dependent helicase activity is dispensable for the physiological functions of Recql4 W Castillo-Tandazo, MF Smeets, V Murphy, R Liu, C Hodson, J Heierhorst, ... PLoS Genetics 15 (7), e1008266, 2019 | 23 | 2019 |
Quantitative non-canonical amino acid tagging (QuaNCAT) proteomics identifies distinct patterns of protein synthesis rapidly induced by hypertrophic agents in cardiomyocytes … R Liu, JW Kenney, A Manousopoulou, HE Johnston, M Kamei, CH Woelk, ... Molecular & Cellular Proteomics 15 (10), 3170-3189, 2016 | 23 | 2016 |
A 14-mer peptide from HSP70 protein is the critical epitope which enhances NK activity against tumor cells in vivo H Zhang, R Liu, W Huang Immunological investigations 36 (3), 233-246, 2007 | 22 | 2007 |
A high-throughput screening assay for eukaryotic elongation factor 2 kinase inhibitors T Xiao, R Liu, CG Proud, MW Wang Acta Pharmaceutica Sinica B 6 (6), 557-563, 2016 | 18 | 2016 |
Proapoptotic BIM impacts B lymphoid homeostasis by limiting the survival of mature B cells in a cell-autonomous manner R Liu, A King, P Bouillet, DM Tarlinton, A Strasser, J Heierhorst Frontiers in immunology 9, 592, 2018 | 14 | 2018 |
ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress R Liu, A King, NC Hoch, C Chang, GL Kelly, AJ Deans, J Heierhorst DNA repair 57, 29-34, 2017 | 13 | 2017 |
The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity. Nat Commun 9: 5406 JR Becker, R Cuella-Martin, M Barazas, R Liu, C Oliveira, AW Oliver, ... | 5 | 2018 |
The ASCIZ-DYNLL1 Axis Is Essential for TLR4-Mediated Antibody Responses and NF-κB Pathway Activation R Liu, A King, D Tarlinton, J Heierhorst Molecular and Cellular Biology, 2021 | 4 | 2021 |