An RGD–oligolysine peptide: a prototype construct for integrin-mediated gene delivery RP Harbottle, RG Cooper, SL Hart, A Ladhoff, T McKay, AM Knight, ... Human gene therapy 9 (7), 1037-1047, 1998 | 297 | 1998 |
CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium L Zhang, B Button, SE Gabriel, S Burkett, Y Yan, MH Skiadopoulos, ... PLoS biology 7 (7), e1000155, 2009 | 232 | 2009 |
NRF2 orchestrates the metabolic shift during induced pluripotent stem cell reprogramming KE Hawkins, S Joy, JMKM Delhove, VN Kotiadis, E Fernandez, ... Cell reports 14 (8), 1883-1891, 2016 | 171 | 2016 |
Clinical challenges and future therapeutic approaches for neuronal ceroid lipofuscinosis SE Mole, G Anderson, HA Band, SF Berkovic, JD Cooper, SMK Holthaus, ... The Lancet Neurology 18 (1), 107-116, 2019 | 164 | 2019 |
Expression of Smac/DIABLO in ovarian carcinoma cells induces apoptosis via a caspase-9-mediated pathway IA McNeish, S Bell, T McKay, T Tenev, M Marani, NR Lemoine Experimental cell research 286 (2), 186-198, 2003 | 137 | 2003 |
Influenza M2 envelope protein augments avian influenza hemagglutinin pseudotyping of lentiviral vectors T McKay, M Patel, RJ Pickles, LG Johnson, JC Olsen Gene therapy 13 (8), 715-724, 2006 | 117 | 2006 |
Survivin interacts with Smac/DIABLO in ovarian carcinoma cells but is redundant in Smac-mediated apoptosis IA McNeish, R Lopes, SJ Bell, TR McKay, M Fernandez, M Lockley, ... Experimental cell research 302 (1), 69-82, 2005 | 110 | 2005 |
Notch signaling through Jagged-1 is necessary to initiate chondrogenesis in human bone marrow stromal cells but must be switched off to complete chondrogenesis RA Oldershaw, SR Tew, AM Russell, K Meade, R Hawkins, TR McKay, ... Stem Cells 26 (3), 666-674, 2008 | 106 | 2008 |
Procaspase 3 expression in ovarian carcinoma cells increases survivin transcription which can be countered with a dominant-negative mutant, survivin T34A; a combination gene … TR McKay, S Bell, T Tenev, V Stoll, R Lopes, NR Lemoine, IA McNeish Oncogene 22 (23), 3539-3547, 2003 | 99 | 2003 |
The role of hypoxia in stem cell potency and differentiation KE Hawkins, TV Sharp, TR McKay Regenerative medicine 8 (6), 771-782, 2013 | 97 | 2013 |
MicroRNA miR-107 is overexpressed in pituitary adenomas and inhibits the expression of aryl hydrocarbon receptor-interacting protein in vitro G Trivellin, H Butz, J Delhove, S Igreja, HS Chahal, V Zivkovic, T McKay, ... American Journal of Physiology-Endocrinology and Metabolism 303 (6), E708-E719, 2012 | 93 | 2012 |
Shed syndecan-2 inhibits angiogenesis G De Rossi, AR Evans, E Kay, A Woodfin, TR McKay, S Nourshargh, ... Journal of cell science 127 (21), 4788-4799, 2014 | 78 | 2014 |
Cell signalling pathways underlying induced pluripotent stem cell reprogramming K Hawkins, S Joy, T McKay World journal of stem cells 6 (5), 620, 2014 | 77 | 2014 |
Antiproliferative and antimigratory effects of a novel YAP–TEAD interaction inhibitor identified using in silico molecular docking SA Smith, RB Sessions, DK Shoemark, C Williams, R Ebrahimighaei, ... Journal of medicinal chemistry 62 (3), 1291-1305, 2019 | 71 | 2019 |
Hyperosmolarity regulates SOX9 mRNA posttranscriptionally in human articular chondrocytes SR Tew, MJ Peffers, TR McKay, ET Lowe, WS Khan, TE Hardingham, ... American Journal of Physiology-Cell Physiology 297 (4), C898-C906, 2009 | 63 | 2009 |
Lentiviral transduction of the murine lung provides efficient pseudotype and developmental stage-dependent cell-specific transgene expression SMK Buckley, SJ Howe, V Sheard, NJ Ward, C Coutelle, AJ Thrasher, ... Gene Therapy 15 (16), 1167-1175, 2008 | 62 | 2008 |
Fine genetic mapping of the Batten disease locus (CLN3) by haplotype analysis and demonstration of allelic association with chromosome 16p microsatellite loci HM Mitchison, AD Thompson, JC Mulley, HM Kozman, RI Richards, ... Genomics 16 (2), 455-460, 1993 | 54 | 1993 |
In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters SMK Buckley, JMKM Delhove, DP Perocheau, R Karda, AA Rahim, ... Scientific reports 5 (1), 11842, 2015 | 51 | 2015 |
FGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development L Guasti, WCC Sze, T McKay, R Grose, PJ King Molecular and cellular endocrinology 371 (1-2), 182-188, 2013 | 50 | 2013 |
BMI-1 extends proliferative potential of human bronchial epithelial cells while retaining their mucociliary differentiation capacity MM Munye, A Shoemark, RA Hirst, JM Delhove, TV Sharp, TR McKay, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 312 (2 …, 2017 | 49 | 2017 |