| CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering P Mali, J Aach, PB Stranges, KM Esvelt, M Moosburner, S Kosuri, L Yang, ... Nature biotechnology 31 (9), 833-838, 2013 | 2347 | 2013 |
| Next-generation digital information storage in DNA GM Church, Y Gao, S Kosuri Science 337 (6102), 1628-1628, 2012 | 1538 | 2012 |
| Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription F Zhang, L Cong, S Lodato, S Kosuri, GM Church, P Arlotta Nature biotechnology 29 (2), 149-153, 2011 | 1210 | 2011 |
| Large-scale de novo DNA synthesis: technologies and applications S Kosuri, GM Church Nature methods 11 (5), 499-507, 2014 | 1024 | 2014 |
| Causes and effects of N-terminal codon bias in bacterial genes DB Goodman, GM Church, S Kosuri Science 342 (6157), 475-479, 2013 | 640 | 2013 |
| Composability of regulatory sequences controlling transcription and translation in Escherichia coli S Kosuri, DB Goodman, G Cambray, VK Mutalik, Y Gao, AP Arkin, D Endy, ... Proceedings of the National Academy of Sciences 110 (34), 14024-14029, 2013 | 491 | 2013 |
| Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips S Kosuri, N Eroshenko, EM LeProust, M Super, J Way, JB Li, GM Church Nature biotechnology 28 (12), 1295-1299, 2010 | 457* | 2010 |
| Refactoring bacteriophage T7 LY Chan, S Kosuri, D Endy Molecular systems biology 1 (1), 2005.0018, 2005 | 427 | 2005 |
| Engineering an allosteric transcription factor to respond to new ligands ND Taylor, AS Garruss, R Moretti, S Chan, MA Arbing, D Cascio, ... Nature methods 13 (2), 177-183, 2016 | 329 | 2016 |
| Probing the limits of genetic recoding in essential genes MJ Lajoie, S Kosuri, JA Mosberg, CJ Gregg, D Zhang, GM Church Science 342 (6156), 361-363, 2013 | 173 | 2013 |
| Assembly of nucleic acid sequences in emulsions GM Church, RC Terry, S Kosuri, D Zhang US Patent 10,202,628, 2019 | 159 | 2019 |
| Structural and functional characterization of G protein–coupled receptors with deep mutational scanning EM Jones, NB Lubock, AJ Venkatakrishnan, J Wang, AM Tseng, JM Paggi, ... Elife 9, e54895, 2020 | 129 | 2020 |
| Multiplexed gene synthesis in emulsions for exploring protein functional landscapes C Plesa, AM Sidore, NB Lubock, D Zhang, S Kosuri Science 359 (6373), 343-347, 2018 | 129 | 2018 |
| A multiplexed assay for exon recognition reveals that an unappreciated fraction of rare genetic variants cause large-effect splicing disruptions R Chong, KD Insigne, D Yao, CP Burghard, J Wang, YHE Hsiao, ... Molecular cell 73 (1), 183-194. e8, 2019 | 124 | 2019 |
| Metagenomic mining of regulatory elements enables programmable species-selective gene expression NI Johns, ALC Gomes, SS Yim, A Yang, T Blazejewski, CS Smillie, ... Nature methods 15 (5), 323-329, 2018 | 107 | 2018 |
| Transcription activator-like effectors F Zhang, L Cong, S Kosuri, GM Church US Patent 9,499,592, 2016 | 102 | 2016 |
| Highly parallel genome variant engineering with CRISPR–Cas9 MJ Sadhu, JS Bloom, L Day, JJ Siegel, S Kosuri, L Kruglyak Nature genetics 50 (4), 510-514, 2018 | 88 | 2018 |
| Systematic Dissection of Sequence Elements Controlling σ70 Promoters Using a Genomically Encoded Multiplexed Reporter Assay in Escherichia coli G Urtecho, AD Tripp, KD Insigne, H Kim, S Kosuri Biochemistry 58 (11), 1539-1551, 2018 | 87 | 2018 |
| Common genetic risk variants identified in the SPARK cohort support DDHD2 as a candidate risk gene for autism N Matoba, D Liang, H Sun, N Aygün, JC McAfee, JE Davis, LM Raffield, ... Translational psychiatry 10 (1), 265, 2020 | 86 | 2020 |
| Engineered CO2 fixing microorganisms producing carbon-based products of interest DA Berry, DE Robertson, FA Skraly, BD Green, CP Ridley, S Kosuri, ... US Patent 7,981,647, 2011 | 85 | 2011 |
George ChurchHarvard Medical School確認したメール アドレス: harvard.edu
