The spectrum of latent tuberculosis: rethinking the biology and intervention strategies CE Barry 3rd, HI Boshoff, V Dartois, T Dick, S Ehrt, JA Flynn, ... Nature Reviews Microbiology 7 (12), 845-855, 2009 | 1667 | 2009 |
Spiroindolones, a potent compound class for the treatment of malaria M Rottmann, C McNamara, BKS Yeung, MCS Lee, B Zou, B Russell, ... science 329 (5996), 1175-1180, 2010 | 1203 | 2010 |
Linezolid for treatment of chronic extensively drug-resistant tuberculosis M Lee, J Lee, MW Carroll, H Choi, S Min, T Song, LE Via, LC Goldfeder, ... New England Journal of Medicine 367 (16), 1508-1518, 2012 | 710 | 2012 |
The association between sterilizing activity and drug distribution into tuberculosis lesions B Prideaux, LE Via, MD Zimmerman, S Eum, J Sarathy, P O'brien, C Chen, ... Nature medicine 21 (10), 1223-1227, 2015 | 473 | 2015 |
Spirotetrahydro β-carbolines (spiroindolones): a new class of potent and orally efficacious compounds for the treatment of malaria BKS Yeung, B Zou, M Rottmann, SB Lakshminarayana, SH Ang, ... Journal of medicinal chemistry 53 (14), 5155-5164, 2010 | 458 | 2010 |
The path of anti-tuberculosis drugs: from blood to lesions to mycobacterial cells V Dartois Nature Reviews Microbiology 12 (3), 159-167, 2014 | 438 | 2014 |
An adenosine nucleoside inhibitor of dengue virus Z Yin, YL Chen, W Schul, QY Wang, F Gu, J Duraiswamy, RR Kondreddi, ... Proceedings of the National Academy of Sciences 106 (48), 20435-20439, 2009 | 394 | 2009 |
Heterogeneity in tuberculosis pathology, microenvironments and therapeutic responses A Lenaerts, CE Barry III, V Dartois Immunological reviews 264 (1), 288-307, 2015 | 349 | 2015 |
Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing YJ Zhang, MC Reddy, TR Ioerger, AC Rothchild, V Dartois, BM Schuster, ... Cell 155 (6), 1296-1308, 2013 | 336 | 2013 |
A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy K Pethe, PC Sequeira, S Agarwalla, K Rhee, K Kuhen, WY Phong, V Patel, ... Nature communications 1 (1), 57, 2010 | 317 | 2010 |
Inflammatory signaling in human tuberculosis granulomas is spatially organized MJ Marakalala, RM Raju, K Sharma, YJ Zhang, EA Eugenin, B Prideaux, ... Nature medicine 22 (5), 531-538, 2016 | 296 | 2016 |
ClpP of Bacillus subtilis is required for competence development, motility, degradative enzyme synthesis, growth at high temperature and sporulation T Msadek, V Dartois, F Kunst, ML Herbaud, F Denizot, G Rapoport Molecular microbiology 27 (5), 899-914, 1998 | 286 | 1998 |
High-sensitivity MALDI-MRM-MS imaging of moxifloxacin distribution in tuberculosis-infected rabbit lungs and granulomatous lesions B Prideaux, V Dartois, D Staab, DM Weiner, A Goh, LE Via, CE Barry III, ... Analytical chemistry 83 (6), 2112-2118, 2011 | 285 | 2011 |
Comprehensive analysis of methods used for the evaluation of compounds against Mycobacterium tuberculosis SG Franzblau, MA DeGroote, SH Cho, K Andries, E Nuermberger, ... Tuberculosis 92 (6), 453-488, 2012 | 255 | 2012 |
Nitric oxide prevents a pathogen-permissive granulocytic inflammation during tuberculosis BB Mishra, RR Lovewell, AJ Olive, G Zhang, W Wang, E Eugenin, ... Nature microbiology 2 (7), 1-11, 2017 | 248 | 2017 |
NTM drug discovery: status, gaps and the way forward ML Wu, DB Aziz, V Dartois, T Dick Drug discovery today 23 (8), 1502-1519, 2018 | 229 | 2018 |
Cloning, nucleotide sequence and expression in Escherichia coli of a lipase gene from Bacillus subtilis 168 V Dartois, A Baulard, K Schanck, C Colson Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1131 (3 …, 1992 | 209 | 1992 |
Pharmacokinetic evaluation of the penetration of antituberculosis agents in rabbit pulmonary lesions MC Kjellsson, LE Via, A Goh, D Weiner, KM Low, S Kern, G Pillai, ... Antimicrobial agents and chemotherapy 56 (1), 446-457, 2012 | 204 | 2012 |
Anti-tuberculosis treatment strategies and drug development: challenges and priorities VA Dartois, EJ Rubin Nature Reviews Microbiology 20 (11), 685-701, 2022 | 197 | 2022 |
Immune activation of the host cell induces drug tolerance in Mycobacterium tuberculosis both in vitro and in vivo Y Liu, S Tan, L Huang, RB Abramovitch, KH Rohde, MD Zimmerman, ... Journal of Experimental Medicine 213 (5), 809-825, 2016 | 186 | 2016 |