Discovery and characterization of natural tropolones as inhibitors of the antibacterial target CapF from Staphylococcus aureus K Nakano, T Chigira, T Miyafusa, S Nagatoishi, JMM Caaveiro, K Tsumoto Scientific reports 5 (1), 15337, 2015 | 32 | 2015 |
Identification of small-molecule inhibitors of the human S100B–p53 interaction and evaluation of their activity in human melanoma cells C Yoshimura, T Miyafusa, K Tsumoto Bioorganic & medicinal chemistry 21 (5), 1109-1115, 2013 | 24 | 2013 |
Crystal structure of the C-terminal domain of Mu phage central spike and functions of bound calcium ion K Harada, E Yamashita, A Nakagawa, T Miyafusa, K Tsumoto, T Ueno, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (1), 284-291, 2013 | 22 | 2013 |
Disruption of cell adhesion by an antibody targeting the cell-adhesive intermediate (X-dimer) of human P-cadherin S Kudo, JMM Caaveiro, S Nagatoishi, T Miyafusa, T Matsuura, Y Sudou, ... Scientific reports 7 (1), 39518, 2017 | 20 | 2017 |
Dynamic elements govern the catalytic activity of CapE, a capsular polysaccharide-synthesizing enzyme from Staphylococcus aureus T Miyafusa, JMM Caaveiro, Y Tanaka, K Tsumoto FEBS letters 587 (23), 3824-3830, 2013 | 19 | 2013 |
Crystal structure of the capsular polysaccharide synthesizing protein CapE of Staphylococcus aureus T Miyafusa, JMM Caaveiro, Y Tanaka, ME Tanner, K Tsumoto Bioscience reports 33 (3), e00043, 2013 | 19 | 2013 |
Backbone circularization coupled with optimization of connecting segment in effectively improving the stability of granulocyte-colony stimulating factor T Miyafusa, R Shibuya, W Nishima, R Ohara, C Yoshida, S Honda ACS Chemical Biology 12 (10), 2690-2696, 2017 | 18 | 2017 |
Crystal structure of the enzyme CapF of Staphylococcus aureus reveals a unique architecture composed of two functional domains T Miyafusa, JMM Caaveiro, Y Tanaka, K Tsumoto Biochemical Journal 443 (3), 671-680, 2012 | 17 | 2012 |
Epiregulin recognition mechanisms by anti-epiregulin antibody 9E5: Structural, functional, and molecular dynamics simulation analyses Y Kado, E Mizohata, S Nagatoishi, M Iijima, K Shinoda, T Miyafusa, ... Journal of Biological Chemistry 291 (5), 2319-2330, 2016 | 12 | 2016 |
Structural and thermodynamic characterization of the self-adhesive properties of human P-cadherin S Kudo, JMM Caaveiro, T Miyafusa, S Goda, K Ishii, T Matsuura, Y Sudou, ... Molecular BioSystems 8 (8), 2050-2053, 2012 | 11 | 2012 |
AlphaScreen-based homogeneous assay using a pair of 25-residue artificial proteins for high-throughput analysis of non-native IgG Y Senga, H Imamura, T Miyafusa, H Watanabe, S Honda Scientific Reports 7 (1), 12466, 2017 | 10 | 2017 |
New family members of FG repeat proteins and their unexplored roles during phase separation Y Shinkai, M Kuramochi, T Miyafusa Frontiers in Cell and Developmental Biology 9, 708702, 2021 | 9 | 2021 |
Stabilization of backbone‐circularized protein is attained by synergistic gains in enthalpy of folded structure and entropy of unfolded structure R Shibuya, T Miyafusa, S Honda The FEBS Journal 287 (8), 1554-1575, 2020 | 7 | 2020 |
Structural insights into the backbone-circularized granulocyte colony-stimulating factor containing a short connector T Miyafusa, R Shibuya, S Honda Biochemical and biophysical research communications 500 (2), 224-228, 2018 | 5 | 2018 |
Expression, purification, crystallization and preliminary diffraction analysis of CapF, a capsular polysaccharide-synthesis enzyme from Staphylococcus aureus T Miyafusa, Y Tanaka, M Kuroda, T Ohta, K Tsumoto Acta Crystallographica Section F: Structural Biology and Crystallization …, 2008 | 5 | 2008 |
Effect of backbone circularization on colloidal stability: Compaction of unfolded structures improves aggregation resistance of granulocyte colony-stimulating factor R Shibuya, T Miyafusa, H Imamura, A Ooishi, S Honda International Journal of Pharmaceutics 605, 120774, 2021 | 4 | 2021 |
Local disorder of the C-terminal segment of the heavy chain as a common sign of stressed antibodies evidenced with a peptide affinity probe specific to non-native IgG T Miyafusa, H Watanabe, S Honda International Journal of Biological Macromolecules 182, 1697-1703, 2021 | 3 | 2021 |
Generation of ubiquitin-based binder with an inserted active peptide T Miyafusa, K Hirota, S Honda Biochemical and biophysical research communications 503 (4), 3162-3166, 2018 | 1 | 2018 |
Designing monomeric IFNγ: the significance of domain-swapped dimer structure in IFNγ immune responses Y Goto, T Miyafusa, S Honda bioRxiv, 2024.02. 18.580912, 2024 | | 2024 |
Determination of the optimal connector length to enhance stability of backbone‐circularized granulocyte colony‐stimulating factor Y Yasuzawa, R Shibuya, Y Senga, T Miyafusa, S Honda FEBS Open Bio 13 (10), 1910-1921, 2023 | | 2023 |