Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa V Busskamp, J Duebel, D Balya, M Fradot, TJ Viney, S Siegert, AC Groner, ... science 329 (5990), 413-417, 2010 | 774 | 2010 |
Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs J Krol, V Busskamp, I Markiewicz, MB Stadler, S Ribi, J Richter, J Duebel, ... Cell 141 (4), 618-631, 2010 | 592 | 2010 |
Partial recovery of visual function in a blind patient after optogenetic therapy JA Sahel, E Boulanger-Scemama, C Pagot, A Arleo, F Galluppi, JN Martel, ... Nature medicine 27 (7), 1223-1229, 2021 | 561 | 2021 |
A spike sorting toolbox for up to thousands of electrodes validated with ground truth recordings in vitro and in vivo P Yger, GLB Spampinato, E Esposito, B Lefebvre, S Deny, C Gardella, ... Elife 7, e34518, 2018 | 342 | 2018 |
The primordial, blue-cone color system of the mouse retina S Haverkamp, H Wässle, J Duebel, T Kuner, GJ Augustine, G Feng, ... Journal of Neuroscience 25 (22), 5438-5445, 2005 | 322 | 2005 |
Functional Fluorescent Ca2+ Indicator Proteins in Transgenic Mice under TET Control MT Hasan, RW Friedrich, T Euler, ME Larkum, G Giese, M Both, J Duebel, ... PLoS biology 2 (6), e163, 2004 | 287 | 2004 |
Generation of storable retinal organoids and retinal pigmented epithelium from adherent human iPS cells in xeno-free and feeder-free conditions S Reichman, A Slembrouck, G Gagliardi, A Chaffiol, A Terray, C Nanteau, ... Stem cells 35 (5), 1176-1188, 2017 | 233 | 2017 |
Targeting channelrhodopsin-2 to ON-bipolar cells with vitreally administered AAV restores ON and OFF visual responses in blind mice E Macé, R Caplette, O Marre, A Sengupta, A Chaffiol, P Barbe, ... Molecular Therapy 23 (1), 7-16, 2015 | 218 | 2015 |
Red‐shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina A Sengupta, A Chaffiol, E Macé, R Caplette, M Desrosiers, M Lampič, ... EMBO molecular medicine 8 (11), 1248-1264, 2016 | 190 | 2016 |
Two-photon imaging reveals somatodendritic chloride gradient in retinal ON-type bipolar cells expressing the biosensor Clomeleon J Duebel, S Haverkamp, W Schleich, G Feng, GJ Augustine, T Kuner, ... Neuron 49 (1), 81-94, 2006 | 189 | 2006 |
A new promoter allows optogenetic vision restoration with enhanced sensitivity in macaque retina A Chaffiol, R Caplette, C Jaillard, E Brazhnikova, M Desrosiers, E Dubus, ... Molecular Therapy 25 (11), 2546-2560, 2017 | 158 | 2017 |
Characterization and transplantation of CD73-positive photoreceptors isolated from human iPSC-derived retinal organoids G Gagliardi, KB M'Barek, A Chaffiol, A Slembrouck-Brec, JB Conart, ... Stem Cell Reports 11 (3), 665-680, 2018 | 145 | 2018 |
Noninvasive gene delivery to foveal cones for vision restoration H Khabou, M Garita-Hernandez, A Chaffiol, S Reichman, C Jaillard, ... JCI insight 3 (2), 2018 | 130 | 2018 |
Optogenetic therapy: high spatiotemporal resolution and pattern discrimination compatible with vision restoration in non-human primates G Gauvain, H Akolkar, A Chaffiol, F Arcizet, MA Khoei, M Desrosiers, ... Communications biology 4 (1), 125, 2021 | 111 | 2021 |
Restoration of visual function by transplantation of optogenetically engineered photoreceptors M Garita-Hernandez, M Lampič, A Chaffiol, L Guibbal, F Routet, ... Nature communications 10 (1), 4524, 2019 | 109 | 2019 |
Optogenetics J Duebel, K Marazova, JA Sahel Current opinion in ophthalmology 26 (3), 226-232, 2015 | 108 | 2015 |
Genetically timed, activity-sensor and rainbow transsynaptic viral tools Z Boldogkői, K Balint, GB Awatramani, D Balya, V Busskamp, TJ Viney, ... Nature Methods 6 (2), 127-130, 2009 | 104 | 2009 |
AAV-mediated gene delivery to 3D retinal organoids derived from human induced pluripotent stem cells M Garita-Hernandez, F Routet, L Guibbal, H Khabou, L Toualbi, ... International journal of molecular sciences 21 (3), 994, 2020 | 74 | 2020 |
Optogenetic light sensors in human retinal organoids M Garita-Hernandez, L Guibbal, L Toualbi, F Routet, A Chaffiol, ... Frontiers in neuroscience 12, 789, 2018 | 58 | 2018 |
The thioredoxin encoded by the rod-derived cone viability factor gene protects cone photoreceptors against oxidative stress X Mei, A Chaffiol, C Kole, Y Yang, G Millet-Puel, E Clérin, N Aït-Ali, ... Antioxidants & redox signaling 24 (16), 909-923, 2016 | 55 | 2016 |