| Mitochondrial dysfunction prevents repolarization of inflammatory macrophages J Van den Bossche, J Baardman, NA Otto, S van der Velden, AE Neele, ... Cell reports 17 (3), 684-696, 2016 | 696 | 2016 |
| PCSK9 monoclonal antibodies reverse the pro-inflammatory profile of monocytes in familial hypercholesterolaemia SJ Bernelot Moens, AE Neele, J Kroon, FM Van Der Valk, ... European heart journal 38 (20), 1584-1593, 2017 | 171 | 2017 |
| Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions MA Hoeksema, MJJ Gijbels, J Van den Bossche, S van der Velden, ... EMBO molecular medicine 6 (9), 1124-1132, 2014 | 165 | 2014 |
| Analysis of genetically diverse macrophages reveals local and domain-wide mechanisms that control transcription factor binding and function VM Link, SH Duttke, HB Chun, IR Holtman, E Westin, MA Hoeksema, ... Cell 173 (7), 1796-1809. e17, 2018 | 159 | 2018 |
| Targeting CD40-induced TRAF6 signaling in macrophages reduces atherosclerosis TTP Seijkens, CM van Tiel, PJH Kusters, D Atzler, O Soehnlein, ... Journal of the American College of Cardiology 71 (5), 527-542, 2018 | 156 | 2018 |
| Epigenetic regulation of monocyte and macrophage function MA Hoeksema, MPJ de Winther Antioxidants & redox signaling 25 (14), 758-774, 2016 | 120 | 2016 |
| Hypercholesterolemia‐induced priming of hematopoietic stem and progenitor cells aggravates atherosclerosis T Seijkens, MA Hoeksema, L Beckers, E Smeets, S Meiler, J Levels, ... The FASEB Journal 28 (5), 2202-2213, 2014 | 118 | 2014 |
| Macrophage polarization: the epigenetic point of view J Van den Bossche, AE Neele, MA Hoeksema, MPJ De Winther Current opinion in lipidology 25 (5), 367-373, 2014 | 101 | 2014 |
| High-density lipoproteins exert pro-inflammatory effects on macrophages via passive cholesterol depletion and PKC-NF-κB/STAT1-IRF1 signaling EPC van Der Vorst, K Theodorou, Y Wu, MA Hoeksema, P Goossens, ... Cell metabolism 25 (1), 197-207, 2017 | 97 | 2017 |
| Molecular pathways regulating macrophage polarization: implications for atherosclerosis MA Hoeksema, JL Stöger, MPJ de Winther Current atherosclerosis reports 14, 254-263, 2012 | 95 | 2012 |
| IFN-γ priming of macrophages represses a part of the inflammatory program and attenuates neutrophil recruitment MA Hoeksema, BP Scicluna, M Boshuizen, S Van Der Velden, AE Neele, ... The Journal of Immunology 194 (8), 3909-3916, 2015 | 79 | 2015 |
| Epigenetic pathways in macrophages emerge as novel targets in atherosclerosis AE Neele, J Van den Bossche, MA Hoeksema, MPJ De Winther European journal of pharmacology 763, 79-89, 2015 | 77 | 2015 |
| Inhibiting epigenetic enzymes to improve atherogenic macrophage functions J Van den Bossche, AE Neele, MA Hoeksema, F De Heij, MCS Boshuizen, ... Biochemical and biophysical research communications 455 (3-4), 396-402, 2014 | 74 | 2014 |
| Nature and nurture of tissue-specific macrophage phenotypes MA Hoeksema, CK Glass Atherosclerosis 281, 159-167, 2019 | 49 | 2019 |
| A PPARγ-Bnip3 axis couples adipose mitochondrial fusion-fission balance to systemic insulin sensitivity MJ Tol, R Ottenhoff, M Van Eijk, N Zelcer, J Aten, SM Houten, D Geerts, ... Diabetes 65 (9), 2591-2605, 2016 | 47 | 2016 |
| Arginase-1 deficiency regulates arginine concentrations and NOS2-mediated NO production during endotoxemia KAP Wijnands, MA Hoeksema, DM Meesters, NMS van den Akker, ... PloS one 9 (1), e86135, 2014 | 47 | 2014 |
| Myeloid IκBα deficiency promotes atherogenesis by enhancing leukocyte recruitment to the plaques P Goossens, MN Vergouwe, MJJ Gijbels, DMJ Curfs, JHG Van Woezik, ... PloS one 6 (7), e22327, 2011 | 45 | 2011 |
| NDF, a nucleosome-destabilizing factor that facilitates transcription through nucleosomes J Fei, H Ishii, MA Hoeksema, F Meitinger, GA Kassavetis, CK Glass, ... Genes & development 32 (9-10), 682-694, 2018 | 42 | 2018 |
| Interferon-β promotes macrophage foam cell formation by altering both cholesterol influx and efflux mechanisms MCS Boshuizen, MA Hoeksema, AE Neele, S van der Velden, ... Cytokine 77, 220-226, 2016 | 42 | 2016 |
| Treatment with Trichuris suis soluble products during monocyte-to-macrophage differentiation reduces inflammatory responses through epigenetic remodeling MA Hoeksema, LC Laan, JJ Postma, RD Cummings, MPJ de Winther, ... The FASEB Journal 30 (8), 2826, 2016 | 34 | 2016 |
Menno de WintherProfessor of Vascular Immune Cell BiologyVerified email at amsterdamumc.nl
