|In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration|
K Suzuki, Y Tsunekawa, R Hernandez-Benitez, J Wu, J Zhu, EJ Kim, ...
Nature 540 (7631), 144-149, 2016
|Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and …|
Y Hiroshima, Y Zhang, T Murakami, A Maawy, S Miwa, M Yamamoto, ...
Oncotarget 5 (23), 12346, 2014
|Establishment of a patient-derived orthotopic Xenograft (PDOX) model of HER-2-positive cervical cancer expressing the clinical metastatic pattern|
Y Hiroshima, Y Zhang, N Zhang, A Maawy, S Mii, M Yamamoto, F Uehara, ...
PloS one 10 (2), e0117417, 2015
|Efficacy of Tumor-Targeting Salmonella A1-R on a Melanoma Patient-Derived Orthotopic Xenograft (PDOX) Nude-Mouse Model|
M Yamamoto, M Zhao, Y Hiroshima, Y Zhang, E Shurell, FC Eilber, ...
PLoS One 11 (8), e0160882, 2016
|Tumor-targeting Salmonella typhimurium A1-R arrests a chemo-resistant patient soft-tissue sarcoma in nude mice|
Y Hiroshima, M Zhao, Y Zhang, N Zhang, A Maawy, T Murakami, S Mii, ...
PloS one 10 (8), e0134324, 2015
|Patient-derived orthotopic xenograft (PDOX) nude mouse model of soft-tissue sarcoma more closely mimics the patient behavior in contrast to the subcutaneous ectopic model|
Y Hiroshima, Y Zhang, N Zhang, F Uehara, A Maawy, T Murakami, S Mii, ...
Anticancer research 35 (2), 697-701, 2015
|Invading cancer cells are predominantly in G0/G1 resulting in chemoresistance demonstrated by real-time FUCCI imaging|
S Yano, S Miwa, S Mii, Y Hiroshima, F Uehara, M Yamamoto, H Kishimoto, ...
Cell Cycle 13 (6), 953-960, 2014
|RECK forms cowbell-shaped dimers and inhibits matrix metalloproteinase-catalyzed cleavage of fibronectin|
A Omura, T Matsuzaki, K Mio, T Ogura, M Yamamoto, A Fujita, K Okawa, ...
Journal of Biological Chemistry 284 (6), 3461-3469, 2009
|Intraperitoneal administration of tumor-targeting Salmonella typhimurium A1-R inhibits disseminated human ovarian cancer and extends survival in nude mice|
Y Matsumoto, S Miwa, Y Zhang, M Zhao, S Yano, F Uehara, M Yamamoto, ...
Oncotarget 6 (13), 11369, 2015
|Spatial–temporal FUCCI imaging of each cell in a tumor demonstrates locational dependence of cell cycle dynamics and chemoresponsiveness|
S Yano, Y Zhang, S Miwa, Y Tome, Y Hiroshima, F Uehara, M Yamamoto, ...
Cell Cycle 13 (13), 2110-2119, 2014
|Efficacy of Tumor‐Targeting Salmonella Typhimurium A1‐R on Nude Mouse Models of Metastatic and Disseminated Human Ovarian Cancer|
Y Matsumoto, S Miwa, Y Zhang, Y Hiroshima, S Yano, F Uehara, ...
Journal of cellular biochemistry 115 (11), 1996-2003, 2014
|Tumor-Targeting Salmonella typhimurium A1-R in Combination with Trastuzumab Eradicates HER-2-Positive Cervical Cancer Cells in Patient-Derived Mouse Models|
Y Hiroshima, Y Zhang, M Zhao, N Zhang, T Murakami, A Maawy, S Mii, ...
PloS one 10 (6), e0120358, 2015
|Antitumor effects of a water-soluble extract from Maitake (Grifola frondosa) on human gastric cancer cell lines|
K Shomori, M Yamamoto, I Arifuku, K Teramachi, H Ito
Oncology reports 22 (3), 615-620, 2009
|Color-coding cancer and stromal cells with genetic reporters in a patient-derived orthotopic xenograft (PDOX) model of pancreatic cancer enhances fluorescence-guided surgery|
S Yano, Y Hiroshima, A Maawy, H Kishimoto, A Suetsugu, S Miwa, ...
Cancer gene therapy 22 (7), 344-350, 2015
|In vivo reprogramming of wound-resident cells generates skin epithelial tissue|
M Kurita, T Araoka, T Hishida, DD O’keefe, Y Takahashi, A Sakamoto, ...
Nature 561 (7722), 243-247, 2018
|Targeting tumors with a killer-reporter adenovirus for curative fluorescence-guided surgery of soft-tissue sarcoma|
S Yano, S Miwa, H Kishimoto, F Uehara, H Tazawa, M Toneri, ...
Oncotarget 6 (15), 13133, 2015
|Involvement of the Reck tumor suppressor protein in maternal and embryonic vascular remodeling in mice|
EPS Chandana, Y Maeda, A Ueda, H Kiyonari, N Oshima, M Yamamoto, ...
BMC developmental biology 10 (1), 1-13, 2010
|Inhibition of spontaneous and experimental lung metastasis of soft-tissue sarcoma by tumor-targeting Salmonella typhimurium A1-R|
S Miwa, Y Zhang, KE Baek, F Uehara, S Yano, M Yamamoto, Y Hiroshima, ...
Oncotarget 5 (24), 12849, 2014
|Experimental curative fluorescence-guided surgery of highly invasive glioblastoma multiforme selectively labeled with a killer-reporter adenovirus|
S Yano, S Miwa, H Kishimoto, M Toneri, Y Hiroshima, M Yamamoto, ...
Molecular Therapy 23 (7), 1182-1188, 2015
|Cell-cycle fate-monitoring distinguishes individual chemosensitive and chemoresistant cancer cells in drug-treated heterogeneous populations demonstrated by real-time FUCCI imaging|
S Miwa, S Yano, H Kimura, M Yamamoto, M Toneri, Y Matsumoto, ...
Cell Cycle 14 (4), 621-629, 2015