|γH2AX foci analysis for monitoring DNA double-strand break repair: strengths, limitations and optimization|
M Löbrich, A Shibata, A Beucher, A Fisher, M Ensminger, AA Goodarzi, ...
Cell cycle 9 (4), 662-669, 2010
|ATM and Artemis promote homologous recombination of radiation‐induced DNA double‐strand breaks in G2|
A Beucher, J Birraux, L Tchouandong, O Barton, A Shibata, S Conrad, ...
The EMBO journal 28 (21), 3413-3427, 2009
|Factors determining DNA double‐strand break repair pathway choice in G2 phase|
A Shibata, S Conrad, J Birraux, V Geuting, O Barton, A Ismail, ...
The EMBO journal 30 (6), 1079-1092, 2011
|53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair|
AT Noon, A Shibata, N Rief, M Löbrich, GS Stewart, PA Jeggo, ...
Nature cell biology 12 (2), 177, 2010
|DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities|
A Shibata, D Moiani, AS Arvai, J Perry, SM Harding, MM Genois, R Maity, ...
Molecular cell 53 (1), 7-18, 2014
|Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G2/M checkpoint arrest|
A Shibata, O Barton, AT Noon, K Dahm, D Deckbar, AA Goodarzi, ...
Molecular and cellular biology 30 (13), 3371-3383, 2010
|Sensitization to radiation and alkylating agents by inhibitors of poly (ADP-ribose) polymerase is enhanced in cells deficient in DNA double-strand break repair|
DA Löser, A Shibata, AK Shibata, LJ Woodbine, PA Jeggo, AJ Chalmers
Molecular cancer therapeutics 9 (6), 1775-1787, 2010
|Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair|
L Woodbine, H Brunton, AA Goodarzi, A Shibata, PA Jeggo
Nucleic acids research 39 (16), 6986-6997, 2011
|DNA double-strand break repair in a cellular context|
A Shibata, PA Jeggo
Clinical oncology 26 (5), 243-249, 2014
|DNA double-strand break resection occurs during non-homologous end joining in G1 but is distinct from resection during homologous recombination|
R Biehs, M Steinlage, O Barton, S Juhász, J Künzel, J Spies, A Shibata, ...
Molecular cell 65 (4), 671-684. e5, 2017
|DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells|
H Sato, A Niimi, T Yasuhara, TBM Permata, Y Hagiwara, M Isono, ...
Nature communications 8 (1), 1751, 2017
|Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection|
A Kakarougkas, A Ismail, Y Katsuki, R Freire, A Shibata, PA Jeggo
Nucleic acids research 41 (22), 10298-10311, 2013
|Opposing roles for 53BP1 during homologous recombination|
A Kakarougkas, A Ismail, K Klement, AA Goodarzi, S Conrad, R Freire, ...
Nucleic acids research 41 (21), 9719-9731, 2013
|Parp-1 deficiency causes an increase of deletion mutations and insertions/rearrangements in vivo after treatment with an alkylating agent|
A Shibata, N Kamada, K Masumura, T Nohmi, S Kobayashi, H Teraoka, ...
Oncogene 24 (8), 1328, 2005
|Regulation of repair pathway choice at two-ended DNA double-strand breaks|
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 803, 51-55, 2017
|Visualisation of γH2AX foci caused by heavy ion particle traversal; distinction between core track versus non-track damage|
NI Nakajima, H Brunton, R Watanabe, A Shrikhande, R Hirayama, ...
PloS one 8 (8), e70107, 2013
|BRCA1 directs the repair pathway to homologous recombination by promoting 53BP1 dephosphorylation|
M Isono, A Niimi, T Oike, Y Hagiwara, H Sato, R Sekine, Y Yoshida, ...
Cell reports 18 (2), 520-532, 2017
|Differential involvement of phosphatidylinositol 3‐kinase‐related protein kinases in hyperphosphorylation of replication protein A2 in response to replication‐mediated DNA …|
R Sakasai, K Shinohe, Y Ichijima, N Okita, A Shibata, K Asahina, ...
Genes to Cells 11 (3), 237-246, 2006
|SETDB1, HP1 and SUV39 promote repositioning of 53BP1 to extend resection during homologous recombination in G2 cells|
M Alagoz, Y Katsuki, H Ogiwara, T Ogi, A Shibata, A Kakarougkas, ...
Nucleic acids research 43 (16), 7931-7944, 2015
|Analysis of human syndromes with disordered chromatin reveals the impact of heterochromatin on the efficacy of ATM-dependent G2/M checkpoint arrest|
H Brunton, AA Goodarzi, AT Noon, A Shrikhande, RS Hansen, PA Jeggo, ...
Molecular and cellular biology 31 (19), 4022-4035, 2011