Ordered and dynamic assembly of single spliceosomes AA Hoskins, LJ Friedman, SS Gallagher, DJ Crawford, EG Anderson, ... Science 331 (6022), 1289-1295, 2011 | 315 | 2011 |
The spliceosome: a flexible, reversible macromolecular machine AA Hoskins, MJ Moore Trends in biochemical sciences 37 (5), 179-188, 2012 | 277 | 2012 |
Visualizing the splicing of single pre-mRNA molecules in whole cell extract DJ Crawford, AA Hoskins, LJ Friedman, J Gelles, MJ Moore Rna 14 (1), 170-179, 2008 | 112 | 2008 |
Alternative spliceosome assembly pathways revealed by single-molecule fluorescence microscopy I Shcherbakova, AA Hoskins, LJ Friedman, V Serebrov, IR Corrêa, MQ Xu, ... Cell reports 5 (1), 151-165, 2013 | 93 | 2013 |
SF3b1 mutations associated with myelodysplastic syndromes alter the fidelity of branchsite selection in yeast TJ Carrocci, DM Zoerner, JC Paulson, AA Hoskins Nucleic acids research 45 (8), 4837-4852, 2017 | 79 | 2017 |
Single-molecule colocalization FRET evidence that spliceosome activation precedes stable approach of 5′ splice site and branch site DJ Crawford, AA Hoskins, LJ Friedman, J Gelles, MJ Moore Proceedings of the National Academy of Sciences 110 (17), 6783-6788, 2013 | 74 | 2013 |
Domain Organization of Salmonella typhimurium Formylglycinamide Ribonucleotide Amidotransferase Revealed by X-ray Crystallography, R Anand, AA Hoskins, JA Stubbe, SE Ealick Biochemistry 43 (32), 10328-10342, 2004 | 74 | 2004 |
Structural analysis of multi-helical RNAs by NMR–SAXS/WAXS: application to the U4/U6 di-snRNA G Cornilescu, AL Didychuk, ML Rodgers, LA Michael, JE Burke, ... Journal of Molecular Biology 428 (5), 777-789, 2016 | 53 | 2016 |
Design and construction of a multiwavelength, micromirror total internal reflectance fluorescence microscope J Larson, M Kirk, EA Drier, W O'brien, JF MacKay, LJ Friedman, ... Nature protocols 9 (10), 2317-2328, 2014 | 52 | 2014 |
Single molecule analysis reveals reversible and irreversible steps during spliceosome activation AA Hoskins, ML Rodgers, LJ Friedman, J Gelles, MJ Moore elife 5, e14166, 2016 | 46 | 2016 |
Strategies from UW-Madison for rescuing biomedical research in the US J Kimble, WM Bement, Q Chang, BL Cox, NR Drinkwater, RL Gourse, ... Elife 4, e09305, 2015 | 45 | 2015 |
New insights into the spliceosome by single molecule fluorescence microscopy AA Hoskins, J Gelles, MJ Moore Current opinion in chemical biology 15 (6), 864-870, 2011 | 43 | 2011 |
Structural and functional modularity of the U2 snRNP in pre-mRNA splicing C van der Feltz, AA Hoskins Critical reviews in biochemistry and molecular biology 54 (5), 443-465, 2019 | 42 | 2019 |
Ribonucleoprotein purification and characterization using RNA Mango SSS Panchapakesan, ML Ferguson, EJ Hayden, X Chen, AA Hoskins, ... Rna 23 (10), 1592-1599, 2017 | 38 | 2017 |
The FtsLB subcomplex of the bacterial divisome is a tetramer with an uninterrupted FtsL helix linking the transmembrane and periplasmic regions SGF Condon, DA Mahbuba, CR Armstrong, G Diaz-Vazquez, SJ Craven, ... Journal of Biological Chemistry 293 (5), 1623-1641, 2018 | 37 | 2018 |
The formylglycinamide ribonucleotide amidotransferase complex from Bacillus subtilis: metabolite-mediated complex formation AA Hoskins, R Anand, SE Ealick, JA Stubbe Biochemistry 43 (32), 10314-10327, 2004 | 37 | 2004 |
Conformational dynamics of stem II of the U2 snRNA ML Rodgers, US Tretbar, A Dehaven, AA Alwan, G Luo, HM Mast, ... Rna 22 (2), 225-236, 2016 | 35 | 2016 |
Dynamics and consequences of spliceosome E complex formation JD Larson, AA Hoskins elife 6, e27592, 2017 | 34 | 2017 |
Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily, M Morar, R Anand, AA Hoskins, JA Stubbe, SE Ealick Biochemistry 45 (50), 14880-14895, 2006 | 34 | 2006 |
Visualizing cellular machines with colocalization single molecule microscopy JD Larson, ML Rodgers, AA Hoskins Chemical Society Reviews 43 (4), 1189-1200, 2014 | 32 | 2014 |