Jason H Yang
Jason H Yang
Rutgers New Jersey Medical School
Verified email at - Homepage
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Antibiotics induce redox-related physiological alterations as part of their lethality
DJ Dwyer*, PA Belenky*, JH Yang*, IC MacDonald, JD Martell, ...
Proceedings of the National Academy of Sciences 111 (20), E2100-E2109, 2014
Antibiotic efficacy is linked to bacterial cellular respiration
MA Lobritz*, P Belenky*, CBM Porter, A Gutierrez, JH Yang, EG Schwarz, ...
Proceedings of the National Academy of Sciences, 201509743, 2015
Carbon Sources Tune Antibiotic Susceptibility in Pseudomonas aeruginosa via Tricarboxylic Acid Cycle Control
S Meylan, CBM Porter*, JH Yang*, P Belenky, A Gutierrez, MA Lobritz, ...
Cell Chemical Biology, 2017
A white-box machine learning approach for revealing antibiotic mechanisms of action
JH Yang, SN Wright, M Hamblin, D McCloskey, MA Alcantar, ...
Cell 177 (6), 1649-1661. e9, 2019
Clinically relevant mutations in core metabolic genes confer antibiotic resistance
AJ Lopatkin, SC Bening, AL Manson, JM Stokes, MA Kohanski, ...
Science 371 (6531), eaba0862, 2021
Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function
JH Yang*, P Bhargava*, D McCloskey, N Mao, BO Palsson, JJ Collins
Cell Host & Microbe, 2017
Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate
AJ Lopatkin, JM Stokes, EJ Zheng, JH Yang, MK Takahashi, L You, ...
Nature Microbiology 4 (12), 2109-2117, 2019
Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP
V Sample*, LM DiPilato*, JH Yang*, Q Ni, JJ Saucerman, J Zhang, ...
Nature chemical biology 8 (4), 375-382, 2012
Antibiotic efficacy—context matters
JH Yang*, SC Bening*, JJ Collins
Current Opinion in Microbiology 39, 73-80, 2017
Comparing McRoberts' and Rubin's maneuvers for initial management of shoulder dystocia: an objective evaluation
ED Gurewitsch, EJ Kim, JH Yang, KE Outland, MK McDonald, RH Allen
American journal of obstetrics and gynecology 192 (1), 153-160, 2005
Applications of machine learning to the problem of antimicrobial resistance: An emerging model for translational research
MN Anahtar, JH Yang, S Kanjilal
Journal of Clinical Microbiology, JCM. 01260-20, 2021
Computational models reduce complexity and accelerate insight into cardiac signaling networks
JH Yang, JJ Saucerman
Circulation research 108 (1), 85-97, 2011
PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to β-adrenergic signaling
JH Yang, RK Polanowska-Grabowska, JS Smith, CW Shields IV, ...
Journal of molecular and cellular cardiology 66, 83-93, 2014
Phospholemman is a negative feed-forward regulator of Ca2+ in β-adrenergic signaling, accelerating β-adrenergic inotropy
JH Yang, JJ Saucerman
Journal of molecular and cellular cardiology 52 (5), 1048-1055, 2012
Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality
N Takahashi*, CC Gruber*, JH Yang, X Liu, D Braff, CN Yashaswini, ...
Proceedings of the National Academy of Sciences, 201707466, 2017
Digital Insights Into Nucleotide Metabolism and Antibiotic Treatment Failure
AJ Lopatkin*, JH Yang*
Frontiers in Digital Health 3 (583468), 1-12, 2021
Growth and stress tolerance comprise independent metabolic strategies critical for Staphylococcus aureus infection
GL Kim, TA Hooven, J Norambuena, B Li, JM Boyd, JH Yang, D Parker
mbio 12 (3), 10.1128/mbio. 00814-21, 2021
Biomonitoring and precision health in deep space supported by artificial intelligence
RT Scott, LM Sanders, EL Antonsen, JJA Hastings, S Park, G Mackintosh, ...
Nature Machine Intelligence 5 (3), 196-207, 2023
A comprehensive update to the Mycobacterium tuberculosis H37Rv reference genome
P Chitale, AD Lemenze, EC Fogarty, A Shah, C Grady, AR Odom-Mabey, ...
Nature communications 13 (1), 7068, 2022
Simulating complicated human birth for research and training
EJ Kim, RH Allen, JH Yang, MK McDonald, W Tam, ED Gurewitsch
The 26th Annual International Conference of the IEEE Engineering in Medicine …, 2004
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Articles 1–20