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Sophie E Darch
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Density-dependent fitness benefits in quorum-sensing bacterial populations
SE Darch, SA West, K Winzer, SP Diggle
Proceedings of the National Academy of Sciences 109 (21), 8259-8263, 2012
3222012
The biogeography of polymicrobial infection
A Stacy, L McNally, SE Darch, SP Brown, M Whiteley
Nature Reviews Microbiology 14 (2), 93-105, 2016
2862016
Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection
SE Darch, A McNally, F Harrison, J Corander, HL Barr, K Paszkiewicz, ...
Scientific reports 5 (1), 7649, 2015
1532015
Spatial determinants of quorum signaling in a Pseudomonas aeruginosa infection model
SE Darch, O Simoska, M Fitzpatrick, JP Barraza, KJ Stevenson, ...
Proceedings of the National Academy of Sciences 115 (18), 4779-4784, 2018
1412018
Pseudomonas aeruginosa Aggregate Formation in an Alginate Bead Model System Exhibits In Vivo-Like Characteristics
M Sønderholm, KN Kragh, K Koren, TH Jakobsen, SE Darch, M Alhede, ...
Applied and environmental microbiology 83 (9), e00113-17, 2017
1282017
Phage inhibit pathogen dissemination by targeting bacterial migrants in a chronic infection model
SE Darch, KN Kragh, EA Abbott, T Bjarnsholt, JJ Bull, M Whiteley
MBio 8 (2), 10.1128/mbio. 00240-17, 2017
722017
Quantifying microbial chatter: scanning electrochemical microscopy as a tool to study interactions in biofilms
SE Darch, D Koley
Proceedings of the Royal Society A 474 (2220), 20180405, 2018
312018
Discovery of dual-activity small-molecule ligands of Pseudomonas aeruginosa LpxA and LpxD using SPR and X-ray crystallography
KG Kroeck, MD Sacco, EW Smith, X Zhang, D Shoun, A Akhtar, SE Darch, ...
Scientific Reports 9 (1), 15450, 2019
212019
Same game, different players: emerging pathogens of the CF lung
AD Gannon, SE Darch
MBio 12 (1), 10.1128/mbio. 01217-20, 2021
152021
Pseudomonas aeruginosa Production of Hydrogen Cyanide Leads to Airborne Control of Staphylococcus aureus Growth in Biofilm and In Vivo Lung Environments
S Létoffé, Y Wu, SE Darch, C Beloin, M Whiteley, L Touqui, JM Ghigo
MBio 13 (5), e02154-22, 2022
142022
Evolution of bacterial “frenemies”
SE Darch, CB Ibberson, M Whiteley
MBio 8 (3), 10.1128/mbio. 00675-17, 2017
122017
Group B Streptococcus drives major transcriptomic changes in the colonic epithelium
K Domínguez, AK Lindon, J Gibbons, SE Darch, TM Randis
Infection and Immunity 91 (7), e00035-23, 2023
32023
Tools for the real-time assessment of a pseudomonas aeruginosa infection model
AD Gannon, SE Darch
JoVE (Journal of Visualized Experiments), e62420, 2021
32021
Structure-Based Ligand Design Targeting Pseudomonas aeruginosa LpxA in Lipid A Biosynthesis
MD Sacco, K Defrees, X Zhang, W Lawless, E Nwanochie, A Balsizer, ...
ACS Infectious Diseases 8 (7), 1231-1240, 2022
22022
Exploring antimicrobial tolerance and social dynamics of bacterial aggregates in the CF lung
S Darch, K Kragh, M Fitzpatrick, O Simoska, J Barraza, E Abbott, ...
PEDIATRIC PULMONOLOGY 53, 270-271, 2018
12018
Response to ‘Refined analyses suggest that recombination is a minor source of genomic diversity in Pseudomonas aeruginosa chronic cystic fibrosis infections’ by
SE Darch, A McNally, J Corander, SP Diggle
Microbial Genomics 2 (3), 2016
12016
Show me the SNPs. How bacterial sex generates diversity in the cystic fibrosis lung
SE Darch, M Whiteley
American Journal of Respiratory and Critical Care Medicine 191 (7), 725-727, 2015
12015
High-Resolution Methods to Study Microbial Interactions in Biofilms
K Dominguez, A Gannon, CD Miller, SE Darch
Multispecies Biofilms: Technologically Advanced Methods to Study Microbial …, 2022
2022
Multispecies Biofilms: Technologically Advanced Methods to Study Microbial Communities
KS Kaushik, SE Darch
Springer, 2022
2022
480 Understanding Pseudomonas aeruginosa aggregate interactions with the emerging pathogen Aspergillus fumigatus
A Gannon, S Darch
Journal of Cystic Fibrosis 21, S273, 2022
2022
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Articles 1–20