KLF6, a candidate tumor suppressor gene mutated in prostate cancer G Narla, KE Heath, HL Reeves, D Li, LE Giono, AC Kimmelman, ... Science 294 (5551), 2563-2566, 2001 | 602 | 2001 |
All roads lead to PP 2A: exploiting the therapeutic potential of this phosphatase J Sangodkar, CC Farrington, K McClinch, MD Galsky, DB Kastrinsky, ... The FEBS journal 283 (6), 1004-1024, 2016 | 316 | 2016 |
microRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial–mesenchymal transition A Parikh, C Lee, P Joseph, S Marchini, A Baccarini, V Kolev, C Romualdi, ... Nature communications 5 (1), 2977, 2014 | 285 | 2014 |
A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk G Narla, A DiFeo, HL Reeves, DJ Schaid, J Hirshfeld, E Hod, A Katz, ... Cancer research 65 (4), 1213-1222, 2005 | 268 | 2005 |
Kruppel-like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer HL Reeves, G Narla, O Ogunbiyi, AI Haq, A Katz, S Benzeno, E Hod, ... Gastroenterology 126 (4), 1090-1103, 2004 | 223 | 2004 |
The Kruppel-like factor 6 genotype is associated with fibrosis in nonalcoholic fatty liver disease L Miele, G Beale, G Patman, V Nobili, J Leathart, A Grieco, M Abate, ... Gastroenterology 135 (1), 282-291. e1, 2008 | 222 | 2008 |
Krüppel-like factor-6 promotes preadipocyte differentiation through histone deacetylase 3-dependent repression of DLK1 D Li, S Yea, S Li, Z Chen, G Narla, M Banck, J Laborda, S Tan, ... Journal of Biological Chemistry 280 (29), 26941-26952, 2005 | 218 | 2005 |
Cyclin-dependent kinase inhibition by the KLF6 tumor suppressor protein through interaction with cyclin D1 S Benzeno, G Narla, J Allina, GZ Cheng, HL Reeves, MS Banck, JA Odin, ... Cancer research 64 (11), 3885-3891, 2004 | 204 | 2004 |
Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread G Narla, A DiFeo, S Yao, A Banno, E Hod, HL Reeves, RF Qiao, ... Cancer Research 65 (13), 5761-5768, 2005 | 202 | 2005 |
Mutations in capillary morphogenesis gene-2 result in the allelic disorders juvenile hyaline fibromatosis and infantile systemic hyalinosis O Dowling, A Difeo, MC Ramirez, T Tukel, G Narla, L Bonafe, H Kayserili, ... The American Journal of Human Genetics 73 (4), 957-966, 2003 | 193 | 2003 |
Therapeutic targeting of PP2A CM O’Connor, A Perl, D Leonard, J Sangodkar, G Narla The international journal of biochemistry & cell biology 96, 182-193, 2018 | 180 | 2018 |
Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth J Sangodkar, A Perl, R Tohme, J Kiselar, DB Kastrinsky, N Zaware, ... The Journal of clinical investigation 127 (6), 2081-2090, 2017 | 180 | 2017 |
Frequent inactivation of the tumor suppressor Kruppel‐like factor 6 (KLF6) in hepatocellular carcinoma S Kremer‐Tal, HL Reeves, G Narla, SN Thung, M Schwartz, A Difeo, ... Hepatology 40 (5), 1047-1052, 2004 | 173 | 2004 |
The role of KLF6 and its splice variants in cancer therapy A DiFeo, JA Martignetti, G Narla Drug Resistance Updates 12 (1-2), 1-7, 2009 | 172 | 2009 |
Kruppel-like transcription factor 6 regulates inflammatory macrophage polarization D Date, R Das, G Narla, DI Simon, MK Jain, GH Mahabeleshwar Journal of Biological Chemistry 289 (15), 10318-10329, 2014 | 167 | 2014 |
The apolipoprotein(a) gene is regulated by sex hormones and acute–phase inducers in YAC transgenic mice KA Frazer, G Narla, JL Zhang, EM Rubin Nature genetics 9 (4), 424-431, 1995 | 150 | 1995 |
PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells O Kauko, CM O’Connor, E Kulesskiy, J Sangodkar, A Aakula, S Izadmehr, ... Science translational medicine 10 (450), eaaq1093, 2018 | 142 | 2018 |
KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis G Narla, A DiFeo, Y Fernandez, S Dhanasekaran, F Huang, J Sangodkar, ... The Journal of clinical investigation 118 (8), 2711-2721, 2008 | 136 | 2008 |
Roles of KLF6 and KLF6-SV1 in ovarian cancer progression and intraperitoneal dissemination A DiFeo, G Narla, J Hirshfeld, O Camacho-Vanegas, J Narla, SL Rose, ... Clinical Cancer Research 12 (12), 3730-3739, 2006 | 135 | 2006 |
Selective PP2A enhancement through biased heterotrimer stabilization D Leonard, W Huang, S Izadmehr, CM O’Connor, DD Wiredja, Z Wang, ... Cell 181 (3), 688-701. e16, 2020 | 126 | 2020 |