Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database Nature Genetics 46 (2), 107-115, 2014 | 488 | 2014 |
POLE and POLD1 mutations in 529 kindred with familial colorectal cancer and/or polyposis: review of reported cases and recommendations for genetic testing and surveillance F Bellido, M Pineda, G Aiza, R Valdés-Mas, M Navarro, DA Puente, ... Genetics in Medicine 18 (4), 325-332, 2016 | 267 | 2016 |
Risk of cancer in cases of suspected lynch syndrome without germline mutation M Rodríguez–Soler, L Pérez–Carbonell, C Guarinos, P Zapater, ... Gastroenterology 144 (5), 926-932. e1, 2013 | 254 | 2013 |
Comparison between universal molecular screening for Lynch syndrome and revised Bethesda guidelines in a large population-based cohort of patients with colorectal cancer L Pérez-Carbonell, C Ruiz-Ponte, C Guarinos, C Alenda, A Payá, A Brea, ... Gut 61 (6), 865-872, 2012 | 214 | 2012 |
New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposis L Valle, E Hernández-Illán, F Bellido, G Aiza, A Castillejo, MI Castillejo, ... Human molecular genetics 23 (13), 3506-3512, 2014 | 189 | 2014 |
Prevalence of Lynch syndrome among patients with newly diagnosed endometrial cancers C Egoavil, C Alenda, A Castillejo, A Paya, G Peiro, AB Sánchez-Heras, ... PLoS one 8 (11), e79737, 2013 | 128 | 2013 |
Germline mutations in FAN1 cause hereditary colorectal cancer by impairing DNA repair N Seguí, LB Mina, C Lázaro, R Sanz-Pamplona, T Pons, M Navarro, ... Gastroenterology 149 (3), 563-566, 2015 | 126 | 2015 |
Prevalence of germline MUTYH mutations among Lynch-like syndrome patients A Castillejo, G Vargas, MI Castillejo, M Navarro, VM Barberá, S González, ... European Journal of Cancer 50 (13), 2241-2250, 2014 | 84 | 2014 |
Methylation analysis of MLH1 improves the selection of patients for genetic testing in Lynch syndrome L Pérez-Carbonell, C Alenda, A Payá, A Castillejo, VM Barberá, C Guillén, ... The Journal of Molecular Diagnostics 12 (4), 498-504, 2010 | 83 | 2010 |
Prevalence and Characteristics of MUTYH-Associated Polyposis in Patients with Multiple Adenomatous and Serrated Polyps C Guarinos, M Juárez, C Egoavil, M Rodríguez-Soler, L Pérez-Carbonell, ... Clinical Cancer Research 20 (5), 1158-1168, 2014 | 79 | 2014 |
Molecular karyotype (amplotype) of metastatic colorectal cancer by unbiased arbitrarily primed PCR DNA fingerprinting S Malkhosyan, J Yasuda, JL Soto, T Sekiya, J Yokota, M Perucho Proceedings of the National Academy of Sciences 95 (17), 10170-10175, 1998 | 77 | 1998 |
Histone deacetylase inhibitors induced caspase-independent apoptosis in human pancreatic adenocarcinoma cell lines P García-Morales, A Gómez-Martínez, A Carrato, I Martínez-Lacaci, ... Molecular cancer therapeutics 4 (8), 1222-1230, 2005 | 70 | 2005 |
A new β2 microglobulin mutation found in a melanoma tumor cell line B Perez, R Benitez, MA Fernandez, MR Oliva, JL Soto, S Serrano, ... Tissue Antigens 53 (6), 569-572, 1999 | 66 | 1999 |
Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study AK Win, JG Dowty, JC Reece, G Lee, AS Templeton, JP Plazzer, ... The Lancet Oncology 22 (7), 1014-1022, 2021 | 65 | 2021 |
Imaging cytometry for counting circulating tumor cells: comparative analysis of the CellSearch vs ImageStream systems N López‐Riquelme, A Minguela, F Villar‐Permuy, D Ciprian, A Castillejo, ... Apmis 121 (12), 1139-1143, 2013 | 65 | 2013 |
Mutation analysis of genes that control the G1/S cell cycle in melanoma: TP53, CDKN1A, CDKN2A, and CDKN2B JL Soto, CM Cabrera, S Serrano, MÁ López-Nevot Bmc Cancer 5, 1-9, 2005 | 64 | 2005 |
A polymeric chip for micromanipulation and particle sorting by ultrasounds based on a multilayer configuration I González, LJ Fernández, TE Gómez, J Berganzo, JL Soto, A Carrato Sensors and Actuators B: Chemical 144 (1), 310-317, 2010 | 57 | 2010 |
TGFB1 and TGFBR1 polymorphic variants in relationship to bladder cancer risk and prognosis A Castillejo, N Rothman, C Murta‐Nascimento, N Malats, ... International journal of cancer 124 (3), 608-613, 2009 | 55 | 2009 |
Clinical subtypes and molecular characteristics of serrated polyposis syndrome C Guarinos, C Sánchez–Fortún, M Rodríguez–Soler, L Pérez–Carbonell, ... Clinical Gastroenterology and Hepatology 11 (6), 705-711, 2013 | 54 | 2013 |
Functional significance of concomitant inactivation of hMLH1 and hMSH6 in tumor cells of the microsatellite mutator phenotype S Baranovskaya, JL Soto, M Perucho, SR Malkhosyan Proceedings of the National Academy of Sciences 98 (26), 15107-15112, 2001 | 51 | 2001 |