The mechanism of superoxide production by NADH: ubiquinone oxidoreductase (complex I) from bovine heart mitochondria L Kussmaul, J Hirst Proceedings of the National Academy of Sciences 103 (20), 7607-7612, 2006 | 843 | 2006 |
An inhibitor of oxidative phosphorylation exploits cancer vulnerability JR Molina, Y Sun, M Protopopova, S Gera, M Bandi, C Bristow, T McAfoos, ... Nature medicine 24 (7), 1036-1046, 2018 | 706 | 2018 |
Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria HR Bridges, AJY Jones, MN Pollak, J Hirst Biochemical Journal 462 (3), 475-487, 2014 | 677 | 2014 |
Mitochondrial complex I J Hirst Annual review of biochemistry 82, 551-575, 2013 | 666 | 2013 |
Reversible interconversion of carbon dioxide and formate by an electroactive enzyme T Reda, CM Plugge, NJ Abram, J Hirst Proceedings of the National Academy of Sciences 105 (31), 10654-10658, 2008 | 631 | 2008 |
Bovine complex I is a complex of 45 different subunits J Carroll, IM Fearnley, JM Skehel, RJ Shannon, J Hirst, JE Walker Journal of Biological Chemistry 281 (43), 32724-32727, 2006 | 604 | 2006 |
Structure of mammalian respiratory complex I J Zhu, KR Vinothkumar, J Hirst Nature 536 (7616), 354-358, 2016 | 573 | 2016 |
Reaction of complex metalloproteins studied by protein-film voltammetry FA Armstrong, HA Heering, J Hirst Chemical Society Reviews 26 (3), 169-179, 1997 | 499 | 1997 |
Reversible glutathionylation of complex I increases mitochondrial superoxide formation ER Taylor, F Hurrell, RJ Shannon, TK Lin, J Hirst, MP Murphy Journal of Biological Chemistry 278 (22), 19603-19610, 2003 | 475 | 2003 |
Analysis of the Subunit Composition of Complex I from Bovine Heart Mitochondria* S J Carroll, IM Fearnley, RJ Shannon, J Hirst, JE Walker Molecular & Cellular Proteomics 2 (2), 117-126, 2003 | 468 | 2003 |
The nuclear encoded subunits of complex I from bovine heart mitochondria J Hirst, J Carroll, IM Fearnley, RJ Shannon, JE Walker Biochimica et Biophysica Acta (BBA)-Bioenergetics 1604 (3), 135-150, 2003 | 465 | 2003 |
Architecture of mammalian respiratory complex I KR Vinothkumar, J Zhu, J Hirst Nature 515 (7525), 80-84, 2014 | 456 | 2014 |
The production of reactive oxygen species by complex I J Hirst, MS King, KR Pryde Biochemical Society Transactions 36 (5), 976-980, 2008 | 384 | 2008 |
Reversibility and efficiency in electrocatalytic energy conversion and lessons from enzymes FA Armstrong, J Hirst Proceedings of the National Academy of Sciences 108 (34), 14049-14054, 2011 | 361 | 2011 |
The enigma of the respiratory chain supercomplex D Milenkovic, JN Blaza, NG Larsson, J Hirst Cell metabolism 25 (4), 765-776, 2017 | 340 | 2017 |
Superoxide is produced by the reduced flavin in mitochondrial complex I: a single, unified mechanism that applies during both forward and reverse electron transfer KR Pryde, J Hirst Journal of Biological Chemistry 286 (20), 18056-18065, 2011 | 307 | 2011 |
GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH: ubiquinone oxidoreductase (complex I) IM Fearnley, J Carroll, RJ Shannon, MJ Runswick, JE Walker, J Hirst Journal of Biological Chemistry 276 (42), 38345-38348, 2001 | 298 | 2001 |
Interaction of the mitochondria-targeted antioxidant MitoQ with phospholipid bilayers and ubiquinone oxidoreductases AM James, MS Sharpley, ARB Manas, FE Frerman, J Hirst, RAJ Smith, ... Journal of Biological Chemistry 282 (20), 14708-14718, 2007 | 265 | 2007 |
Towards the molecular mechanism of respiratory complex I J Hirst Biochemical Journal 425 (2), 327-339, 2010 | 244 | 2010 |
Reversible Interconversion of CO2 and Formate by a Molybdenum-Containing Formate Dehydrogenase A Bassegoda, C Madden, DW Wakerley, E Reisner, J Hirst Journal of the American Chemical Society 136 (44), 15473-15476, 2014 | 234 | 2014 |