Koga Tomoaki
Koga Tomoaki
Kumamoto university, Institute of Molecular Embryology and Genetics, Department of Medical Cell Biology
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Gut Microbiota Promotes Obesity-Associated Liver Cancer through PGE2-Mediated Suppression of Antitumor Immunity
TM Loo, F Kamachi, Y Watanabe, S Yoshimoto, H Kanda, Y Arai, ...
Cancer discovery 7 (5), 522-538, 2017
CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt
JH Lim, H Jono, K Komatsu, CH Woo, J Lee, M Miyata, T Matsuno, X Xu, ...
Nature communications 3 (1), 771, 2012
Tumor suppressor CYLD regulates acute lung injury in lethal Streptococcus pneumoniae infections
JH Lim, B Stirling, J Derry, T Koga, H Jono, CH Woo, H Xu, P Bourne, ...
Immunity 27 (2), 349-360, 2007
p53 regulates Toll-like receptor 3 expression and function in human epithelial cell lines
M Taura, A Eguma, MA Suico, T Shuto, T Koga, K Komatsu, T Komune, ...
Molecular and cellular biology 28 (21), 6557-6567, 2008
12-Hydroxyheptadecatrienoic acid promotes epidermal wound healing by accelerating keratinocyte migration via the BLT2 receptor
M Liu, K Saeki, T Matsunobu, T Okuno, T Koga, Y Sugimoto, C Yokoyama, ...
Journal of Experimental Medicine 211 (6), 1063-1078, 2014
TGF‐β induces p65 acetylation to enhance bacteria‐induced NF‐κB activation
H Ishinaga, H Jono, JH Lim, SM Kweon, H Xu, UH Ha, H Xu, T Koga, ...
The EMBO journal 26 (4), 1150-1162, 2007
The crystal structure of the green tea polyphenol (−)-epigallocatechin gallate− transthyretin complex reveals a novel binding site distinct from the thyroxine binding site
M Miyata, T Sato, M Kugimiya, M Sho, T Nakamura, S Ikemizu, M Chirifu, ...
Biochemistry 49 (29), 6104-6114, 2010
Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice
JH Lim, H Jono, T Koga, CH Woo, H Ishinaga, P Bourne, H Xu, UH Ha, ...
PloS one 2 (10), e1032, 2007
A novel role for IκB kinase (IKK) α and IKKβ in ERK-dependent up-regulation of MUC5AC mucin transcription by Streptococcus pneumoniae
U Ha, JH Lim, H Jono, T Koga, A Srivastava, R Malley, J Pouysségur, ...
The Journal of Immunology 178 (3), 1736-1747, 2007
STT3B-dependent posttranslational N-glycosylation as a surveillance system for secretory protein
T Sato, Y Sako, M Sho, M Momohara, MA Suico, T Shuto, H Nishitoh, ...
Molecular cell 47 (1), 99-110, 2012
TLR3 induction by anticancer drugs potentiates poly I: C‐induced tumor cell apoptosis
M Taura, R Fukuda, MA Suico, A Eguma, T Koga, T Shuto, T Sato, ...
Cancer science 101 (7), 1610-1617, 2010
Endoplasmic reticulum (ER) stress induces sirtuin 1 (SIRT1) expression via the PI3K-Akt-GSK3β signaling pathway and promotes hepatocellular injury
T Koga, MA Suico, S Shimasaki, E Watanabe, Y Kai, K Koyama, K Omachi, ...
Journal of Biological Chemistry 290 (51), 30366-30374, 2015
Nontypeable Haemophilus influenzae induces COX-2 and PGE2 expression in lung epithelial cells via activation of p38 MAPK and NF-kappa B
F Xu, Z Xu, R Zhang, Z Wu, JH Lim, T Koga, JD Li, H Shen
Respiratory research 9, 1-9, 2008
Non-steroidal anti-inflammatory drug delays corneal wound healing by reducing production of 12-hydroxyheptadecatrienoic acid, a ligand for leukotriene B4 receptor 2
S Iwamoto, T Koga, M Ohba, T Okuno, M Koike, A Murakami, A Matsuda, ...
Scientific reports 7 (1), 13267, 2017
Inhibition of PDE4B suppresses inflammation by increasing expression of the deubiquitinase CYLD
K Komatsu, JY Lee, M Miyata, J Hyang Lim, H Jono, T Koga, H Xu, C Yan, ...
Nature communications 4 (1), 1684, 2013
Tumor suppressor cylindromatosis acts as a negative regulator for Streptococcus pneumoniae-induced NFAT signaling
T Koga, JH Lim, H Jono, UH Ha, H Xu, H Ishinaga, S Morino, X Xu, C Yan, ...
Journal of Biological Chemistry 283 (18), 12546-12554, 2008
The transforming growth factor-β-Smad3/4 signaling pathway acts as a positive regulator for TLR2 induction by bacteria via a dual mechanism involving functional cooperation …
F Mikami, JH Lim, H Ishinaga, UH Ha, H Gu, T Koga, H Jono, H Kai, JD Li
Journal of Biological Chemistry 281 (31), 22397-22408, 2006
Leukotriene B4 receptor type 2 (BLT2) enhances skin barrier function by regulating tight junction proteins
Y Ishii, K Saeki, M Liu, F Sasaki, T Koga, K Kitajima, C Meno, T Okuno, ...
The FASEB Journal 30 (2), 933-947, 2016
Leukotriene B4 promotes neovascularization and macrophage recruitment in murine wet-type AMD models
F Sasaki, T Koga, M Ohba, K Saeki, T Okuno, K Ishikawa, T Nakama, ...
JCI insight 3 (18), 2018
Endoplasmic reticulum stress increases the expression and function of toll-like receptor-2 in epithelial cells
S Shimasaki, T Koga, T Shuto, MA Suico, T Sato, K Watanabe, ...
Biochemical and biophysical research communications 402 (2), 235-240, 2010
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