Live Cell Imaging Unveils Multiple Domain Requirements for In Vivo Dimerization of the Glucocorticoid Receptor DM Presman, MF Ogara, M Stortz, LD Alvarez, JR Pooley, RL Schiltz, ... PLoS biology 12 (3), e1001813, 2014 | 137 | 2014 |
Synthesis and biological evaluation of novel substituted pyrrolo [1, 2-a] quinoxaline derivatives as inhibitors of the human protein kinase CK2 J Guillon, M Le Borgne, C Rimbault, S Moreau, S Savrimoutou, N Pinaud, ... European Journal of Medicinal Chemistry 65, 205-222, 2013 | 102 | 2013 |
Insights on glucocorticoid receptor activity modulation through the binding of rigid steroids DM Presman, LD Alvarez, V Levi, S Eduardo, MA Digman, MA Martí, ... PloS one 5 (10), e13279, 2010 | 57 | 2010 |
Structure of the glucocorticoid receptor, a flexible protein that can adapt to different ligands AS Veleiro, LD Alvarez, SL Eduardo, G Burton ChemMedChem 5 (5), 649-659, 2010 | 34 | 2010 |
New lead compounds in the search for pure antiglucocorticoids and the dissociation of antiglucocorticoid effects A Pecci, LD Alvarez, AS Veleiro, NR Ceballos, CP Lantos, G Burton The Journal of Steroid Biochemistry and Molecular Biology 113 (3-5), 155-162, 2009 | 27 | 2009 |
Exploring the molecular basis of action of the passive antiglucocorticoid 21-hydroxy-6, 19-epoxyprogesterone LD Álvarez, MA Martí, AS Veleiro, DM Presman, DA Estrin, A Pecci, ... Journal of medicinal chemistry 51 (5), 1352-1360, 2008 | 26 | 2008 |
Hemisuccinate of 21‐hydroxy‐6, 19‐epoxyprogesterone: a tissue‐specific modulator of the glucocorticoid receptor LD Álvarez, MA Martí, AS Veleiro, RI Misico, DA Estrin, A Pecci, G Burton ChemMedChem: Chemistry Enabling Drug Discovery 3 (12), 1869-1877, 2008 | 22 | 2008 |
Ruthenium-catalyzed synthesis of pyrrolo [1, 2-a] quinoxaline derivatives from 1-(2-aminophenyl) pyrroles and sulfoxonium ylides XF Cui, FP Hu, XQ Zhou, ZZ Zhan, GS Huang Synlett 31 (12), 1205-1210, 2020 | 19 | 2020 |
Structure and dynamics of neurosteroid binding to the α1β2γ2 GABAA receptor LD Alvarez, A Pecci The Journal of steroid biochemistry and molecular biology 182, 72-80, 2018 | 19 | 2018 |
Acetic Acid Catalysed One-Pot Synthesis of Pyrrolo [1, 2-a] quinoxaline Derivatives PNM Allan, MI Ostrowska, B Patel Synlett 30 (19), 2148-2152, 2019 | 18 | 2019 |
In Search of GABAA Receptor’s Neurosteroid Binding Sites: Miniperspective LD Alvarez, A Pecci, DA Estrin Journal of Medicinal Chemistry 62 (11), 5250-5260, 2018 | 18 | 2018 |
Exploring the molecular basis of neurosteroid binding to the β3 homopentameric GABAA receptor LD Alvarez, DA Estrin The Journal of Steroid Biochemistry and Molecular Biology 154, 159-167, 2015 | 15 | 2015 |
Synthesis of C (1)–C (11) oxygen-bridged pregnanes AS Veleiro, PJ Taich, LD Alvarez, PH Di Chenna, G Burton Tetrahedron letters 46 (24), 4235-4238, 2005 | 15 | 2005 |
Synthesis and GABAA receptor activity of oxygen-bridged neurosteroid analogs LD Alvarez, AS Veleiro, RF Baggio, MT Garland, VC Edelsztein, H Coirini, ... Bioorganic & medicinal chemistry 16 (7), 3831-3838, 2008 | 14 | 2008 |
Structural insights into the ligand binding domain of the glucocorticoid receptor: a molecular dynamics study NRC Alves, A Pecci, LD Alvarez Journal of Chemical Information and Modeling 60 (2), 794-804, 2019 | 13 | 2019 |
Destabilization of the torsioned conformation of a ligand side chain inverts the LXRβ activity LD Álvarez, MV Dansey, DY Grinman, D Navalesi, GA Samaja, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015 | 13 | 2015 |
Exploring the molecular basis of action of ring D aromatic steroidal antiestrogens LD Alvarez, AS Veleiro, G Burton Proteins: Structure, Function, and Bioinformatics 83 (7), 1297-1306, 2015 | 13 | 2015 |
Synthetic DAF-12 modulators with potential use in controlling the nematode life cycle MV Dansey, LD Alvarez, G Samaja, DS Escudero, AS Veleiro, A Pecci, ... Biochemical Journal 465 (1), 175-184, 2015 | 12 | 2015 |
The Caenorhabditis elegans DAF‐12 nuclear receptor: Structure, dynamics, and interaction with ligands LD Alvarez, PA Manez, DA Estrin, G Burton Proteins: Structure, Function, and Bioinformatics 80 (7), 1798-1809, 2012 | 12 | 2012 |
Neuroprotective action of synthetic steroids with oxygen bridge. Activity on GABAA receptor M Rey, MS Kruse, LD Alvarez, AA Ghini, AS Veleiro, G Burton, H Coirini Experimental neurology 249, 49-58, 2013 | 11 | 2013 |