フォロー
John Mansfield
John Mansfield
Senior Lecturer, Institute of Genetic Medicine, Newcastle University
確認したメール アドレス: nuth.nhs.uk
タイトル
引用先
引用先
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
1958 Birth Cohort Controls Jones Richard W. 18 McArdle Wendy L. 18 Ring ...
Nature 447 (7145), 661-678, 2007
93222007
Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ...
Nature 491 (7422), 119-124, 2012
5248*2012
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
JC Barrett, S Hansoul, DL Nicolae, JH Cho, RH Duerr, JD Rioux, SR Brant, ...
Nature genetics 40 (8), 955-962, 2008
32152008
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
A Franke, DPB McGovern, JC Barrett, K Wang, GL Radford-Smith, ...
Nature genetics 42 (12), 1118-1125, 2010
31252010
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
CA Anderson, G Boucher, CW Lees, A Franke, M D'Amato, KD Taylor, ...
Nature genetics 43 (3), 246-252, 2011
16952011
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
M Parkes, JC Barrett, NJ Prescott, M Tremelling, CA Anderson, SA Fisher, ...
Nature genetics 39 (7), 830-832, 2007
14312007
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
1958 Birth Cohort Controls: Jones Richard W 18 McArdle Wendy L 18 Ring Susan ...
Nature genetics 39 (11), 1329-1337, 2007
14222007
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
KM De Lange, L Moutsianas, JC Lee, CA Lamb, Y Luo, NA Kennedy, ...
Nature genetics 49 (2), 256-261, 2017
11862017
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls
Nature 464 (7289), 713-720, 2010
9302010
The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease
AP Cuthbert, SA Fisher, MM Mirza, K King, J Hampe, PJP Croucher, ...
Gastroenterology 122 (4), 867-874, 2002
9242002
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
I Cleynen, G Boucher, L Jostins, LP Schumm, S Zeissig, T Ahmad, ...
The Lancet 387 (10014), 156-167, 2016
8192016
Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A
S Nejentsev, JMM Howson, NM Walker, J Szeszko, SF Field, HE Stevens, ...
Nature 450 (7171), 887-892, 2007
6992007
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
Data and Analysis Group: Spencer Chris CA chris. spencer@ well. ox. ac. uk 5 ...
Nature genetics 41 (12), 1330-1334, 2009
6222009
Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study
NA Kennedy, GA Heap, HD Green, B Hamilton, C Bewshea, GJ Walker, ...
The lancet Gastroenterology & hepatology 4 (5), 341-353, 2019
5512019
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
SA Fisher, M Tremelling, CA Anderson, R Gwilliam, S Bumpstead, ...
Nature genetics 40 (6), 710-712, 2008
5452008
Novel genetic association between ulcerative colitis and the anti-inflammatory cytokine interleukin-1 receptor antagonist
JC Mansfield, H Holden, JK Tarlow, FS Di Giovine, TL McDowell, ...
Gastroenterology 106 (3), 637-642, 1994
5231994
Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial
S Vermeire, S O'Byrne, M Keir, M Williams, TT Lu, JC Mansfield, CA Lamb, ...
The Lancet 384 (9940), 309-318, 2014
4972014
A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn’s disease and is independent of CARD15 and IBD5
NJ Prescott, SA Fisher, A Franke, J Hampe, CM Onnie, D Soars, ...
Gastroenterology 132 (5), 1665-1671, 2007
3942007
High-density mapping of the MHC identifies a shared role for HLA-DRB1* 01: 03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis
P Goyette, G Boucher, D Mallon, E Ellinghaus, L Jostins, H Huang, ...
Nature genetics 47 (2), 172-179, 2015
3292015
HLA-DQA1* 05 carriage associated with development of anti-drug antibodies to infliximab and adalimumab in patients with Crohn’s disease
A Sazonovs, NA Kennedy, L Moutsianas, GA Heap, DL Rice, M Reppell, ...
Gastroenterology 158 (1), 189-199, 2020
3002020
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