|Essential considerations for using protein–ligand structures in drug discovery|
GL Warren, TD Do, BP Kelley, A Nicholls, SD Warren
Drug Discovery Today 17 (23-24), 1270-1281, 2012
|Categorizing cells on the basis of their chemical profiles: progress in single-cell mass spectrometry|
TJ Comi, TD Do, SS Rubakhin, JV Sweedler
Journal of the American Chemical Society 139 (11), 3920-3929, 2017
|Amyloid β-protein assembly and Alzheimer’s disease: Dodecamers of Aβ42, but not of Aβ40, seed fibril formation|
NJ Economou, MJ Giammona, TD Do, X Zheng, DB Teplow, SK Buratto, ...
Journal of the American Chemical Society 138 (6), 1172-1175, 2016
|Ion mobility spectrometry reveals the mechanism of amyloid formation of Aβ (25–35) and its modulation by inhibitors at the molecular level: epigallocatechin gallate and scyllo …|
C Bleiholder, TD Do, C Wu, NJ Economou, SS Bernstein, SK Buratto, ...
Journal of the American Chemical Society 135 (45), 16926-16937, 2013
|Tau assembly: the dominant role of PHF6 (VQIVYK) in microtubule binding region repeat R3|
P Ganguly, TD Do, L Larini, NE LaPointe, AJ Sercel, MF Shade, ...
The journal of physical chemistry B 119 (13), 4582-4593, 2015
|A novel projection approximation algorithm for the fast and accurate computation of molecular collision cross sections (II). Model parameterization and definition of empirical …|
C Bleiholder, S Contreras, TD Do, MT Bowers
International journal of mass spectrometry 345, 89-96, 2013
|Amyloid β-Protein C-terminal Fragments: Formation of Cylindrins and β-barrels|
TD Do, NE LaPointe, R Nelson, P Krotee, EY Hayden, B Ulrich, S Quan, ...
Journal of the American Chemical Society 138 (2), 549-557, 2016
|Phenylalanine oligomers and fibrils: the mechanism of assembly and the importance of tetramers and counterions|
TD Do, WM Kincannon, MT Bowers
Journal of the American Chemical Society 137 (32), 10080-10083, 2015
|Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS)|
S Sangwan, A Zhao, KL Adams, CK Jayson, MR Sawaya, EL Guenther, ...
Proceedings of the National Academy of Sciences 114 (33), 8770–8775, 2017
|Interactions between amyloid-β and Tau fragments promote aberrant aggregates: implications for amyloid toxicity|
TD Do, NJ Economou, A Chamas, SK Buratto, JE Shea, MT Bowers
The Journal of Physical Chemistry B 118 (38), 11220-11230, 2014
|Initiation of assembly of tau (273-284) and its ΔK280 mutant: an experimental and computational study|
L Larini, MM Gessel, NE LaPointe, TD Do, MT Bowers, SC Feinstein, ...
Physical Chemistry Chemical Physics 15 (23), 8916-8928, 2013
|Amino Acid Metaclusters: Implications of Growth Trends on Peptide Self-Assembly and Structure|
TD Do, NEC de Almeida, NE Lapointe, A Chamas, SC Feinstein, ...
Analytical chemistry 88 (1), 868-876, 2016
|Single cell profiling using ionic liquid matrix-enhanced secondary ion mass spectrometry for neuronal cell type differentiation|
TD Do, TJ Comi, SJB Dunham, SS Rubakhin, JV Sweedler
Analytical chemistry 89 (5), 3078-3086, 2017
|Effects of pH and charge state on peptide assembly: the YVIFL model system|
TD Do, NE LaPointe, NJ Economou, SK Buratto, SC Feinstein, JE Shea, ...
The Journal of Physical Chemistry B 117 (37), 10759-10768, 2013
|Combinatorial discovery through a distributed outreach Program: Investigation of the photoelectrolysis activity of p-type Fe, Cr, Al oxides|
JG Rowley, TD Do, DA Cleary, BA Parkinson
ACS applied materials & interfaces 6 (12), 9046-9052, 2014
|Factors that drive peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants|
TD Do, NE LaPointe, S Sangwan, DB Teplow, SC Feinstein, MR Sawaya, ...
The Journal of Physical Chemistry B 118 (26), 7247-7256, 2014
|Diphenylalanine Self Assembly: Novel Ion Mobility Methods Showing the Essential Role of Water|
TD Do, MT Bowers
Analytical chemistry 87 (8), 4245–4252, 2015
|Oligomerization of the microtubule‐associated protein tau is mediated by its N‐terminal sequences: implications for normal and pathological tau action|
HE Feinstein, SJ Benbow, NE LaPointe, N Patel, S Ramachandran, ...
Journal of neurochemistry 137 (6), 939-954, 2016
|Factors that drive peptide assembly and fibril formation: experimental and theoretical analysis of Sup35 NNQQNY mutants|
TD Do, NJ Economou, NE LaPointe, WM Kincannon, C Bleiholder, ...
The Journal of Physical Chemistry B 117 (28), 8436-8446, 2013
|Exploring the Fundamental Structures of Life: Non‐Targeted, Chemical Analysis of Single Cells and Subcellular Structures|
EK Neumann, TD Do, TJ Comi, JV Sweedler
Angewandte Chemie International Edition 58 (28), 9348-9364, 2019