Yong Zhou
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Membrane potential modulates plasma membrane phospholipid dynamics and K-Ras signaling
Y Zhou, CO Wong, K Cho, D Van Der Hoeven, H Liang, DP Thakur, J Luo, ...
Science 349 (6250), 873-876, 2015
Inhibition of RAS function through targeting an allosteric regulatory site
R Spencer-Smith, A Koide, Y Zhou, RR Eguchi, F Sha, P Gajwani, ...
Nature chemical biology 13 (1), 62-68, 2017
Lipid-sorting specificity encoded in K-Ras membrane anchor regulates signal output
Y Zhou, P Prakash, H Liang, KJ Cho, AA Gorfe, JF Hancock
Cell 168 (1), 239-251. e16, 2017
Ras nanoclusters: Versatile lipid-based signaling platforms
Y Zhou, JF Hancock
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (4), 841-849, 2015
Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90
G Zhang, Z Liu, H Ding, Y Zhou, HA Doan, KWT Sin, ZJ Zhu, R Flores, ...
Nature communications 8 (1), 589, 2017
NSAID injury to the gastrointestinal tract: evidence that NSAIDs interact with phospholipids to weaken the hydrophobic surface barrier and induce the formation of unstable …
LM Lichtenberger, Y Zhou, EJ Dial, RM Raphael
journal of pharmacy and pharmacology 58 (11), 1421-1428, 2006
Insight into NSAID-induced membrane alterations, pathogenesis and therapeutics: characterization of interaction of NSAIDs with phosphatidylcholine
LM Lichtenberger, Y Zhou, V Jayaraman, JR Doyen, RG O'Neil, EJ Dial, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2012
Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae
Y Gambin, N Ariotti, KA McMahon, M Bastiani, E Sierecki, O Kovtun, ...
elife 3, e01434, 2014
Solution pH alters mechanical and electrical properties of phosphatidylcholine membranes: relation between interfacial electrostatics, intramembrane potential, and bending …
Y Zhou, RM Raphael
Biophysical journal 92 (7), 2451-2462, 2007
Signal integration by lipid-mediated spatial cross talk between Ras nanoclusters
Y Zhou, H Liang, T Rodkey, N Ariotti, RG Parton, JF Hancock
Molecular and cellular biology 34 (5), 862-876, 2014
Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling
N Ariotti, MA Fernández-Rojo, Y Zhou, MM Hill, TL Rodkey, KL Inder, ...
Journal of Cell Biology 204 (5), 777-792, 2014
Oncogenic K-Ras binds to an anionic membrane in two distinct orientations: a molecular dynamics analysis
P Prakash, Y Zhou, H Liang, JF Hancock, AA Gorfe
Biophysical journal 110 (5), 1125-1138, 2016
ω-3 polyunsaturated fatty acids direct differentiation of the membrane phenotype in mesenchymal stem cells to potentiate osteogenesis
KR Levental, MA Surma, AD Skinkle, JH Lorent, Y Zhou, C Klose, ...
Science advances 3 (11), eaao1193, 2017
Temporal production of the signaling lipid phosphatidic acid by phospholipase D2 determines the output of extracellular signal-regulated kinase signaling in cancer cells
F Zhang, Z Wang, M Lu, Y Yonekubo, X Liang, Y Zhang, P Wu, Y Zhou, ...
Molecular and cellular biology 34 (1), 84-95, 2014
Inhibition of acid sphingomyelinase depletes cellular phosphatidylserine and mislocalizes K-Ras from the plasma membrane
K Cho, D van der Hoeven, Y Zhou, M Maekawa, X Ma, W Chen, GD Fairn, ...
Molecular and cellular biology 36 (2), 363-374, 2016
Bile acids modulate signaling by functional perturbation of plasma membrane domains
Y Zhou, KN Maxwell, E Sezgin, M Lu, H Liang, JF Hancock, EJ Dial, ...
Journal of Biological Chemistry 288 (50), 35660-35670, 2013
Effect of salicylate on the elasticity, bending stiffness, and strength of SOPC membranes
Y Zhou, RM Raphael
Biophysical journal 89 (3), 1789-1801, 2005
Effect of indomethacin on bile acid-phospholipid interactions: implication for small intestinal injury induced by nonsteroidal anti-inflammatory drugs
Y Zhou, EJ Dial, R Doyen, LM Lichtenberger
American Journal of Physiology-Gastrointestinal and Liver Physiology 298 (5 …, 2010
Distinct binding preferences between Ras and Raf family members and the impact on oncogenic Ras signaling
EM Terrell, DE Durrant, DA Ritt, NE Sealover, E Sheffels, ...
Molecular cell 76 (6), 872-884. e5, 2019
HRAS‐driven cancer cells are vulnerable to TRPML1 inhibition
J Jung, KJ Cho, AK Naji, KN Clemons, CO Wong, M Villanueva, ...
EMBO reports 20 (4), e46685, 2019
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