Degeneration and regeneration of the intervertebral disc: lessons from development LJ Smith, NL Nerurkar, KS Choi, BD Harfe, DM Elliott Disease models & mechanisms 4 (1), 31-41, 2011 | 514 | 2011 |
Evaluation of intervertebral disc cartilaginous endplate structure using magnetic resonance imaging SM Moon, JH Yoder, AC Wright, LJ Smith, EJ Vresilovic, DM Elliott European Spine Journal 22, 1820-1828, 2013 | 164 | 2013 |
Needle puncture injury causes acute and long‐term mechanical deficiency in a mouse model of intervertebral disc degeneration JT Martin, DJ Gorth, EE Beattie, BD Harfe, LJ Smith, DM Elliott Journal of Orthopaedic Research 31 (8), 1276-1282, 2013 | 145 | 2013 |
Translation of an engineered nanofibrous disc-like angle-ply structure for intervertebral disc replacement in a small animal model JT Martin, AH Milby, JA Chiaro, DH Kim, NM Hebela, LJ Smith, DM Elliott, ... Acta biomaterialia 10 (6), 2473-2481, 2014 | 134 | 2014 |
The elastic fibre network of the human lumbar anulus fibrosus: architecture, mechanical function and potential role in the progression of intervertebral disc degeneration LJ Smith, NL Fazzalari European Spine Journal 18, 439-448, 2009 | 134 | 2009 |
IL-1ra delivered from poly(lactic-co-glycolic acid) microspheres attenuates IL-1β-mediated degradation of nucleus pulposus in vitro DJ Gorth, RL Mauck, JA Chiaro, B Mohanraj, NM Hebela, GR Dodge, ... Arthritis research & therapy 14, 1-12, 2012 | 113 | 2012 |
Microstructural heterogeneity directs micromechanics and mechanobiology in native and engineered fibrocartilage WM Han, SJ Heo, TP Driscoll, JF Delucca, CM McLeod, LJ Smith, ... Nature materials 15 (4), 477-484, 2016 | 110 | 2016 |
Long-term mechanical function and integration of an implanted tissue-engineered intervertebral disc SE Gullbrand, BG Ashinsky, ED Bonnevie, DH Kim, JB Engiles, LJ Smith, ... Science translational medicine 10 (468), eaau0670, 2018 | 103 | 2018 |
Elastic fibers enhance the mechanical integrity of the human lumbar anulus fibrosus in the radial direction LJ Smith, S Byers, JJ Costi, NL Fazzalari Annals of biomedical engineering 36, 214-223, 2008 | 94 | 2008 |
Advancing cell therapies for intervertebral disc regeneration from the lab to the clinic: Recommendations of the ORS spine section LJ Smith, L Silverman, D Sakai, CL Le Maitre, RL Mauck, NR Malhotra, ... JOR spine 1 (4), e1036, 2018 | 93 | 2018 |
Translation of an injectable triple-interpenetrating-network hydrogel for intervertebral disc regeneration in a goat model SE Gullbrand, TP Schaer, P Agarwal, JR Bendigo, GR Dodge, W Chen, ... Acta biomaterialia 60, 201-209, 2017 | 91 | 2017 |
Cell therapy for the degenerating intervertebral disc W Tong, Z Lu, L Qin, RL Mauck, HE Smith, LJ Smith, NR Malhotra, ... Translational Research 181, 49-58, 2017 | 91 | 2017 |
Nucleus pulposus cells synthesize a functional extracellular matrix and respond to inflammatory cytokine challenge following long term agarose culture LJ Smith, JA Chiaro, NL Nerurkar, DH Cortes, SD Horava, NM Hebela, ... European cells & materials 22, 291, 2011 | 91 | 2011 |
Regional variations in the density and arrangement of elastic fibres in the anulus fibrosus of the human lumbar disc LJ Smith, NL Fazzalari Journal of anatomy 209 (3), 359-367, 2006 | 91 | 2006 |
Macro-to microscale strain transfer in fibrous tissues is heterogeneous and tissue-specific WM Han, SJ Heo, TP Driscoll, LJ Smith, RL Mauck, DM Elliott Biophysical journal 105 (3), 807-817, 2013 | 88 | 2013 |
Phenotypic stability, matrix elaboration and functional maturation of nucleus pulposus cells encapsulated in photocrosslinkable hyaluronic acid hydrogels DH Kim, JT Martin, DM Elliott, LJ Smith, RL Mauck Acta biomaterialia 12, 21-29, 2015 | 77 | 2015 |
Micromechanical properties of human trabecular bone: a hierarchical investigation using nanoindentation J Norman, JG Shapter, K Short, LJ Smith, NL Fazzalari Journal of Biomedical Materials Research Part A: An Official Journal of The …, 2008 | 76 | 2008 |
A large animal model that recapitulates the spectrum of human intervertebral disc degeneration SE Gullbrand, NR Malhotra, TP Schaer, Z Zawacki, JT Martin, JR Bendigo, ... Osteoarthritis and cartilage 25 (1), 146-156, 2017 | 75 | 2017 |
Multi-scale structural and tensile mechanical response of annulus fibrosus to osmotic loading WM Han, NL Nerurkar, LJ Smith, NT Jacobs, RL Mauck, DM Elliott Annals of biomedical engineering 40, 1610-1621, 2012 | 73 | 2012 |
In Vitro Characterization of a Stem-Cell-Seeded Triple-Interpenetrating-Network Hydrogel for Functional Regeneration of the Nucleus Pulposus LJ Smith, DJ Gorth, BL Showalter, JA Chiaro, EE Beattie, DM Elliott, ... Tissue Engineering Part A 20 (13-14), 1841-1849, 2014 | 67 | 2014 |