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Kakajan Komurov
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Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
JH Taube, JI Herschkowitz, K Komurov, AY Zhou, S Gupta, J Yang, ...
Proceedings of the National Academy of Sciences 107 (35), 15449-15454, 2010
11992010
Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in Braf-Mutant Human Cutaneous Melanoma Cells
YNV Gopal, W Deng, SE Woodman, K Komurov, P Ram, PD Smith, ...
Cancer research 70 (21), 8736-8747, 2010
2792010
Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer
HS Kim, S Mendiratta, J Kim, CV Pecot, JE Larsen, I Zubovych, BY Seo, ...
Cell 155 (3), 552-566, 2013
1932013
Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1α and oxidative phosphorylation in melanoma
YNV Gopal, H Rizos, G Chen, W Deng, DT Frederick, ZA Cooper, ...
Cancer research 74 (23), 7037-7047, 2014
1912014
U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies
MA Smith, GS Choudhary, A Pellagatti, K Choi, LC Bolanos, TD Bhagat, ...
Nature cell biology 21 (5), 640-650, 2019
1862019
Revealing static and dynamic modular architecture of the eukaryotic protein interaction network
K Komurov, M White
Molecular systems biology 3 (1), 110, 2007
1612007
The glucose‐deprivation network counteracts lapatinib‐induced toxicity in resistant ErbB2‐positive breast cancer cells
K Komurov, JT Tseng, M Muller, EG Seviour, TJ Moss, L Yang, D Nagrath, ...
Molecular systems biology 8 (1), 596, 2012
1282012
NetWalker: a contextual network analysis tool for functional genomics
K Komurov, S Dursun, S Erdin, PT Ram
BMC genomics 13, 1-9, 2012
1222012
AMP kinase promotes glioblastoma bioenergetics and tumour growth
RR Chhipa, Q Fan, J Anderson, R Muraleedharan, Y Huang, G Ciraolo, ...
Nature cell biology 20 (7), 823-835, 2018
1192018
Use of data-biased random walks on graphs for the retrieval of context-specific networks from genomic data
K Komurov, MA White, PT Ram
PLoS computational biology 6 (8), e1000889, 2010
1092010
Targeting c-FOS and DUSP1 abrogates intrinsic resistance to tyrosine-kinase inhibitor therapy in BCR-ABL-induced leukemia
M Kesarwani, Z Kincaid, A Gomaa, E Huber, S Rohrabaugh, Z Siddiqui, ...
Nature medicine 23 (4), 472-482, 2017
942017
A calcium-and calpain-dependent pathway determines the response to lenalidomide in myelodysplastic syndromes
J Fang, X Liu, L Bolanos, B Barker, C Rigolino, A Cortelezzi, EN Oliva, ...
Nature medicine 22 (7), 727-734, 2016
772016
Kinome siRNA-phosphoproteomic screen identifies networks regulating AKT signaling
Y Lu, M Muller, D Smith, B Dutta, K Komurov, S Iadevaia, D Ruths, ...
Oncogene 30 (45), 4567-4577, 2011
692011
Myeloid malignancies with chromosome 5q deletions acquire a dependency on an intrachromosomal NF-κB gene network
J Fang, B Barker, L Bolanos, X Liu, A Jerez, H Makishima, S Christie, ...
Cell reports 8 (5), 1328-1338, 2014
682014
Biomarker accessible and chemically addressable mechanistic subtypes of BRAF melanoma
B Eskiocak, EA McMillan, S Mendiratta, RK Kollipara, H Zhang, ...
Cancer discovery 7 (8), 832-851, 2017
602017
IRAK1 is a novel DEK transcriptional target and is essential for head and neck cancer cell survival
AK Adams, LC Bolanos, PJ Dexheimer, RA Karns, BJ Aronow, K Komurov, ...
Oncotarget 6 (41), 43395, 2015
522015
Targeting SRC in mucinous ovarian carcinoma
K Matsuo, M Nishimura, JN Bottsford-Miller, J Huang, K Komurov, ...
Clinical cancer research 17 (16), 5367-5378, 2011
492011
An inflammatory gene signature distinguishes neurofibroma Schwann cells and macrophages from cells in the normal peripheral nervous system
K Choi, K Komurov, JS Fletcher, E Jousma, JA Cancelas, J Wu, N Ratner
Scientific Reports 7 (1), 43315, 2017
462017
Comprehensive mapping of the human kinome to epidermal growth factor receptor signaling
K Komurov, D Padron, T Cheng, M Roth, KP Rosenblatt, MA White
Journal of biological chemistry 285 (27), 21134-21142, 2010
442010
Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer
N Oatman, N Dasgupta, P Arora, K Choi, MV Gawali, N Gupta, ...
Science Advances 7 (7), eabd7459, 2021
422021
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