Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons Y Shi, S Lin, KA Staats, Y Li, WH Chang, ST Hung, E Hendricks, ... Nature medicine 24 (3), 313-325, 2018 | 580 | 2018 |
Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance Z Zhao, AP Sagare, Q Ma, MR Halliday, P Kong, K Kisler, EA Winkler, ... Nature neuroscience 18 (7), 978-987, 2015 | 449 | 2015 |
Divergent selection on opsins drives incipient speciation in Lake Victoria cichlids Y Terai, O Seehausen, T Sasaki, K Takahashi, S Mizoiri, T Sugawara, ... PLoS biology 4 (12), e433, 2006 | 227 | 2006 |
Parallelism of amino acid changes at the RH1 affecting spectral sensitivity among deep-water cichlids from Lakes Tanganyika and Malawi T Sugawara, Y Terai, H Imai, GF Turner, S Koblmüller, C Sturmbauer, ... Proceedings of the National Academy of Sciences 102 (15), 5448-5453, 2005 | 133 | 2005 |
Natural selection of the rhodopsin gene during the adaptive radiation of East African Great Lakes cichlid fishes T Sugawara, Y Terai, N Okada Molecular Biology and Evolution 19 (10), 1807-1811, 2002 | 78 | 2002 |
Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons Y Shi, ST Hung, G Rocha, S Lin, GR Linares, KA Staats, C Seah, Y Wang, ... JCI insight 4 (15), 2019 | 55 | 2019 |
Correlation between nuptial colors and visual sensitivities tuned by opsins leads to species richness in sympatric Lake Victoria cichlid fishes R Miyagi, Y Terai, M Aibara, T Sugawara, H Imai, H Tachida, SI Mzighani, ... Molecular Biology and Evolution 29 (11), 3281-3296, 2012 | 55 | 2012 |
Vertebrate rhodopsin adaptation to dim light via rapid meta-II intermediate formation T Sugawara, H Imai, M Nikaido, Y Imamoto, N Okada Molecular biology and evolution 27 (3), 506-519, 2009 | 53 | 2009 |
Diversification of bitter taste receptor gene family in western chimpanzees T Sugawara, Y Go, T Udono, N Morimura, M Tomonaga, H Hirai, H Imai Molecular biology and evolution 28 (2), 921-931, 2011 | 46 | 2011 |
Reverse Evolution in RH1 for Adaptation of Cichlids to Water Depth in Lake Tanganyika H Nagai, Y Terai, T Sugawara, H Imai, H Nishihara, M Hori, N Okada Molecular Biology and Evolution 28 (6), 1769-1776, 2011 | 44 | 2011 |
Identification of non-taster Japanese macaques for a specific bitter taste N Suzuki, T Sugawara, A Matsui, Y Go, H Hirai, H Imai Primates 51, 285-289, 2010 | 43 | 2010 |
Xenogeneic-free defined conditions for derivation and expansion of human embryonic stem cells with mesenchymal stem cells H Akutsu, M Machida, S Kanzaki, T Sugawara, T Ohkura, N Nakamura, ... Regenerative Therapy 1, 18-29, 2015 | 42 | 2015 |
Eco-Geographical Diversification of Bitter Taste Receptor Genes (TAS2Rs) among Subspecies of Chimpanzees (Pan troglodytes) T Hayakawa, T Sugawara, Y Go, T Udono, H Hirai, H Imai Public Library of Science 7 (8), e43277, 2012 | 36 | 2012 |
Epigenetic-scale comparison of human iPSCs generated by retrovirus, Sendai virus or episomal vectors K Nishino, Y Arai, K Takasawa, M Toyoda, M Yamazaki-Inoue, ... Regenerative Therapy 9, 71-78, 2018 | 19 | 2018 |
β-catenin functions pleiotropically in differentiation and tumorigenesis in mouse embryo-derived stem cells N Okumura, H Akutsu, T Sugawara, T Miura, Y Takezawa, A Hosoda, ... PloS one 8 (5), e63265, 2013 | 15 | 2013 |
Generation of primitive neural stem cells from human fibroblasts using a defined set of factors T Miura, T Sugawara, A Fukuda, R Tamoto, T Kawasaki, A Umezawa, ... Biology open 4 (11), 1595-1607, 2015 | 14 | 2015 |
Investigating cellular identity and manipulating cell fate using induced pluripotent stem cells T Sugawara, K Nishino, A Umezawa, H Akutsu Stem Cell Research & Therapy 3, 1-10, 2012 | 13 | 2012 |
The hsa-miR-302 cluster controls ectodermal differentiation of human pluripotent stem cell via repression of DAZAP2 T Sugawara, T Miura, T Kawasaki, A Umezawa, H Akutsu Regenerative Therapy 15, 1-9, 2020 | 11 | 2020 |
Organoids recapitulate organs? T Sugawara, K Sasaki, H Akutsu Stem Cell Investigation 5, 2018 | 9 | 2018 |
Single-Cell RNA-Seq Reveals LRRC75A-Expressing Cell Population Involved in VEGF Secretion of Multipotent Mesenchymal Stromal/Stem Cells Under Ischemia T Miura, T Kouno, M Takano, T Kuroda, Y Yamamoto, S Kusakawa, ... Stem Cells Translational Medicine 12 (6), 379-390, 2023 | 7 | 2023 |