Multi-scale simulations of cardiac electrophysiology and mechanics using the University of Tokyo heart simulator S Sugiura, T Washio, A Hatano, J Okada, H Watanabe, T Hisada Progress in biophysics and molecular biology 110 (2-3), 380-389, 2012 | 127 | 2012 |
Microtubules modulate the stiffness of cardiomyocytes against shear stress S Nishimura, S Nagai, M Katoh, H Yamashita, Y Saeki, J Okada, T Hisada, ... Circulation Research 98 (1), 81-87, 2006 | 115 | 2006 |
Computer simulation of blood flow, left ventricular wall motion and their interrelationship by fluid-structure interaction finite element method H Watanabe, T Hisada, S Sugiura, J Okada, H Fukunari JSME International Journal Series C Mechanical Systems, Machine Elements and …, 2002 | 99 | 2002 |
Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator J Okada, T Yoshinaga, J Kurokawa, T Washio, T Furukawa, K Sawada, ... Science advances 1 (4), e1400142, 2015 | 89 | 2015 |
Transmural and apicobasal gradients in repolarization contribute to T-wave genesis in human surface ECG J Okada, T Washio, A Maehara, S Momomura, S Sugiura, T Hisada American Journal of Physiology-Heart and Circulatory Physiology 301 (1 …, 2011 | 84 | 2011 |
A three-dimensional simulation model of cardiomyocyte integrating excitation-contraction coupling and metabolism A Hatano, J Okada, T Washio, T Hisada, S Sugiura Biophysical Journal 101 (11), 2601-2610, 2011 | 59 | 2011 |
Multiscale heart simulation with cooperative stochastic cross-bridge dynamics and cellular structures T Washio, J Okada, A Takahashi, K Yoneda, Y Kadooka, S Sugiura, ... Multiscale Modeling & Simulation 11 (4), 965-999, 2013 | 57 | 2013 |
Three-dimensional simulation of calcium waves and contraction in cardiomyocytes using the finite element method J Okada, S Sugiura, S Nishimura, T Hisada American Journal of Physiology-Cell Physiology 288 (3), C510-C522, 2005 | 57 | 2005 |
Approximation for cooperative interactions of a spatially-detailed cardiac sarcomere model T Washio, J Okada, S Sugiura, T Hisada Cellular and molecular bioengineering 5, 113-126, 2012 | 50 | 2012 |
Multi-scale, tailor-made heart simulation can predict the effect of cardiac resynchronization therapy J Okada, T Washio, M Nakagawa, M Watanabe, Y Kadooka, T Kariya, ... Journal of molecular and cellular cardiology 108, 17-23, 2017 | 43 | 2017 |
Patient specific simulation of body surface ECG using the finite element method JUNI OKADA, T Sasaki, T Washio, H Yamashita, T Kariya, Y Imai, ... Pacing and clinical electrophysiology 36 (3), 309-321, 2013 | 41 | 2013 |
A parallel multilevel technique for solving the bidomain equation on a human heart with Purkinje fibers and a torso model T Washio, J Okada, T Hisada SIAM review 52 (4), 717-743, 2010 | 36 | 2010 |
Ventricular fiber optimization utilizing the branching structure T Washio, K Yoneda, J Okada, T Kariya, S Sugiura, T Hisada International Journal for Numerical Methods in Biomedical Engineering 32 (7 …, 2016 | 35 | 2016 |
Effects of an hERG activator, ICA-105574, on electrophysiological properties of canine hearts M Asayama, J Kurokawa, K Shirakawa, H Okuyama, T Kagawa, J Okada, ... Journal of pharmacological sciences 121 (1), 1-8, 2013 | 31 | 2013 |
Distinct functional roles of cardiac mitochondrial subpopulations revealed by a 3D simulation model A Hatano, J Okada, T Washio, T Hisada, S Sugiura Biophysical journal 108 (11), 2732-2739, 2015 | 30 | 2015 |
Study of efficient homogenization algorithms for nonlinear problems: Approximation of a homogenized tangent stiffness to reduce computational cost J Okada, T Washio, T Hisada Computational Mechanics 46, 247-258, 2010 | 30 | 2010 |
A multi-scale heart simulation on massively parallel computers A Hosoi, T Washio, J Okada, Y Kadooka, K Nakajima, T Hisada SC'10: Proceedings of the 2010 ACM/IEEE International Conference for High …, 2010 | 29 | 2010 |
Parallel processing coronary circulation simulation method and simulator apparatus using newton-raphson analysis T Iwamura, T Hisada, S Sugiura, T Washio, J Okada US Patent 10,013,533, 2018 | 24 | 2018 |
Tailor-made heart simulation predicts the effect of cardiac resynchronization therapy in a canine model of heart failure N Panthee, J Okada, T Washio, Y Mochizuki, R Suzuki, H Koyama, M Ono, ... Medical image analysis 31, 46-62, 2016 | 23 | 2016 |
Critical role of cardiac t-tubule system for the maintenance of contractile function revealed by a 3D integrated model of cardiomyocytes A Hatano, J Okada, T Hisada, S Sugiura Journal of biomechanics 45 (5), 815-823, 2012 | 22 | 2012 |