A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain B De Strooper, W Annaert, P Cupers, P Saftig, K Craessaerts, JS Mumm, ... Nature 398 (6727), 518-522, 1999 | 2738 | 1999 |
A ligand-induced extracellular cleavage regulates γ-secretase-like proteolytic activation of Notch1 JS Mumm, EH Schroeter, MT Saxena, A Griesemer, X Tian, DJ Pan, ... Molecular cell 5 (2), 197-206, 2000 | 1132 | 2000 |
On the role of soluble ribonucleic acid in coding for amino acids F Chapeville, F Lipmann, G Ehrenstein, B Weisblum, WJ Ray Jr, S Benzer Proceedings of the National Academy of Sciences 48 (6), 1086-1092, 1962 | 503 | 1962 |
CYP26, a novel mammalian cytochrome P450, is induced by retinoic acid and defines a new family WJ Ray, G Bain, M Yao, DI Gottlieb Journal of Biological Chemistry 272 (30), 18702-18708, 1997 | 376 | 1997 |
Cell surface presenilin-1 participates in the γ-secretase-like proteolysis of Notch WJ Ray, M Yao, J Mumm, EH Schroeter, P Saftig, M Wolfe, DJ Selkoe, ... Journal of Biological Chemistry 274 (51), 36801-36807, 1999 | 357 | 1999 |
Retinoic acid promotes neural and represses mesodermal gene expression in mouse embryonic stem cells in culture G Bain, WJ Ray, M Yao, DI Gottlieb Biochemical and biophysical research communications 223 (3), 691-694, 1996 | 346 | 1996 |
From embryonal carcinoma cells to neurons: the P19 pathway G Bain, WJ Ray, M Yao, DI Gottlieb Bioessays 16 (5), 343-348, 1994 | 312 | 1994 |
Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation L Ma, MA Seager, M Wittmann, M Jacobson, D Bickel, M Burno, K Jones, ... Proceedings of the National Academy of Sciences 106 (37), 15950-15955, 2009 | 310 | 2009 |
The role of APOE4 in disrupting the homeostatic functions of astrocytes and microglia in aging and Alzheimer’s disease CG Fernandez, ME Hamby, ML McReynolds, WJ Ray Frontiers in aging neuroscience 11, 14, 2019 | 254 | 2019 |
Sex-dependent liver gene expression is extensive and largely dependent upon signal transducer and activator of transcription 5b (STAT5b): STAT5b-dependent activation of male … KH Clodfelter, MG Holloway, P Hodor, SH Park, WJ Ray, DJ Waxman Molecular endocrinology 20 (6), 1333-1351, 2006 | 245 | 2006 |
Inhibition of calcineurin-mediated endocytosis and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors prevents amyloid β oligomer-induced synaptic disruption WQ Zhao, F Santini, R Breese, D Ross, XD Zhang, DJ Stone, M Ferrer, ... Journal of Biological Chemistry 285 (10), 7619-7632, 2010 | 228 | 2010 |
Evidence for a physical interaction between presenilin and Notch WJ Ray, M Yao, P Nowotny, J Mumm, W Zhang, JY Wu, R Kopan, ... Proceedings of the National Academy of Sciences 96 (6), 3263-3268, 1999 | 220 | 1999 |
Presenilin complexes with the C-terminal fragments of amyloid precursor protein at the sites of amyloid β-protein generation W Xia, WJ Ray, BL Ostaszewski, T Rahmati, WT Kimberly, MS Wolfe, ... Proceedings of the National Academy of Sciences 97 (16), 9299-9304, 2000 | 198 | 2000 |
Identification of genetic pathways activated by the androgen receptor during the induction of proliferation in the ventral prostate gland PV Nantermet, J Xu, Y Yu, P Hodor, D Holder, S Adamski, MA Gentile, ... Journal of Biological Chemistry 279 (2), 1310-1322, 2004 | 158 | 2004 |
LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease J Majercak, WJ Ray, A Espeseth, A Simon, XP Shi, C Wolffe, K Getty, ... Proceedings of the National Academy of Sciences 103 (47), 17967-17972, 2006 | 110 | 2006 |
Androgen-mediated improvement of body composition and muscle function involves a novel early transcriptional program including IGF1, mechano growth factor, and induction of β … MA Gentile, PV Nantermet, RL Vogel, R Phillips, D Holder, P Hodor, ... Journal of molecular endocrinology 44 (1), 55, 2010 | 102 | 2010 |
A simple procedure for removing contaminating aldehydes and peroxides from aqueous solutions of polyethylene glycols and of nonionic detergents that are based on the … WJ Ray Jr, JM Puvathingal Analytical biochemistry 146 (2), 307-312, 1985 | 102 | 1985 |
Molecular insights into the pathogenesis of Alzheimer's disease and its relationship to normal aging AA Podtelezhnikov, KQ Tanis, M Nebozhyn, WJ Ray, DJ Stone, ... PloS one 6 (12), e29610, 2011 | 96 | 2011 |
Androgenic induction of growth and differentiation in the rodent uterus involves the modulation of estrogen-regulated genetic pathways PV Nantermet, P Masarachia, MA Gentile, B Pennypacker, J Xu, D Holder, ... Endocrinology 146 (2), 564-578, 2005 | 94 | 2005 |
[57] Photochemical oxidation WJ Ray Jr Methods in enzymology 11, 490-497, 1967 | 91 | 1967 |