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Joseph DiDonato
Joseph DiDonato
Staff Scientist, Cleveland Clinic
Verified email at ccf.org
Title
Cited by
Cited by
Year
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
Z Wang, E Klipfell, BJ Bennett, R Koeth, BS Levison, B DuGar, ...
Nature 472 (7341), 57, 2011
54672011
Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis
RA Koeth, Z Wang, BS Levison, JA Buffa, E Org, BT Sheehy, EB Britt, X Fu, ...
Nature medicine 19 (5), 576, 2013
44872013
Immunosuppression by glucocorticoids: inhibition of NF-κB activity through induction of IκB synthesis
N Auphan, JA DiDonato, C Rosette, A Helmberg, M Karin
Science 270 (5234), 286-290, 1995
31791995
A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
JA DiDonato, M Hayakawa, DM Rothwarf, E Zandi, M Karin
Nature 388 (6642), 548, 1997
28881997
NF‐κB and the link between inflammation and cancer
JA DiDonato, F Mercurio, M Karin
Immunological reviews 246 (1), 379-400, 2012
17022012
Gut microbial metabolite TMAO enhances platelet hyperreactivity and thrombosis risk
W Zhu, JC Gregory, E Org, JA Buffa, N Gupta, Z Wang, L Li, X Fu, Y Wu, ...
Cell 165 (1), 111-124, 2016
16712016
Non-lethal inhibition of gut microbial trimethylamine production for the treatment of atherosclerosis
Z Wang, AB Roberts, JA Buffa, BS Levison, W Zhu, E Org, X Gu, Y Huang, ...
Cell 163 (7), 1585-1595, 2015
12182015
Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation.
J DiDonato, F Mercurio, C Rosette, J Wu-Li, H Suyang, S Ghosh, M Karin
Molecular and cellular biology 16 (4), 1295-1304, 1996
10041996
An agonist of toll-like receptor 5 has radioprotective activity in mouse and primate models
LG Burdelya, VI Krivokrysenko, TC Tallant, E Strom, AS Gleiberman, ...
Science 320 (5873), 226-230, 2008
8812008
NF-kappa B activation by ultraviolet light not dependent on a nuclear signal
Y Devary, C Rosette, JA DiDonato, M Karin
Science 261 (5127), 1442-1445, 1993
8191993
Protein carbamylation links inflammation, smoking, uremia and atherogenesis
Z Wang, SJ Nicholls, ER Rodriguez, O Kummu, S Hörkkö, J Barnard, ...
Nature medicine 13 (10), 1176, 2007
7832007
γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO
RA Koeth, BS Levison, MK Culley, JA Buffa, Z Wang, JC Gregory, E Org, ...
Cell metabolism 20 (5), 799-812, 2014
5252014
Transmission of atherosclerosis susceptibility with gut microbial transplantation
JC Gregory, JA Buffa, E Org, Z Wang, BS Levison, W Zhu, MA Wagner, ...
Journal of Biological Chemistry 290 (9), 5647-5660, 2015
5052015
Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B.
JA DiDonato, F Mercurio, M Karin
Molecular and cellular biology 15 (3), 1302-1311, 1995
4661995
NF-κB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-κB-inducing kinase and IκB kinase
M Zamanian-Daryoush, TH Mogensen, JA DiDonato, BRG Williams
Molecular and cellular biology 20 (4), 1278-1290, 2000
4562000
Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential
AB Roberts, X Gu, JA Buffa, AG Hurd, Z Wang, W Zhu, N Gupta, SM Skye, ...
Nature medicine 24 (9), 1407, 2018
4382018
NF-κB is a central regulator of the intestinal epithelial cell innate immune response induced by infection with enteroinvasive bacteria
D Elewaut, JA DiDonato, JM Kim, F Truong, L Eckmann, MF Kagnoff
The Journal of Immunology 163 (3), 1457-1466, 1999
4371999
Activation of NF-κB is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes
NH Purcell, G Tang, C Yu, F Mercurio, JA DiDonato, A Lin
Proceedings of the National Academy of Sciences 98 (12), 6668-6673, 2001
4162001
MyD88 is essential for clearance of Leishmania major: possible role for lipophosphoglycan and Toll‐like receptor 2 signaling
MJ de Veer, JM Curtis, TM Baldwin, JA DiDonato, A Sexton, ...
European journal of immunology 33 (10), 2822-2831, 2003
4062003
An abundant dysfunctional apolipoprotein A1 in human atheroma
Y Huang, JA DiDonato, BS Levison, D Schmitt, L Li, Y Wu, J Buffa, T Kim, ...
Nature medicine 20 (2), 193, 2014
3972014
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